Obstructive sleep apnoea syndrome as a predictor of work disability

Respiratory Medicine

Volumn 103, Issue 7, 2009, Pages 1047-1055

  Sjösten, Noora ^a   Kivimäki, Mika ^a,b   Oksanen, Tuula ^a   Salo, Paula ^a   Saaresranta, Tarja ^c   Virtanen, Marianna ^a   Pentti, Jaana ^a   Vahtera, Jussi ^a  

^a FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

Disability pension; Sickness absence; Sleep apnoea

Indexed keywords

ABSENTEEISM; ADULT; ARTICLE; COMORBIDITY; CONTROLLED STUDY; FEMALE; FINLAND; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; OCCUPATIONAL ACCIDENT; PENSION; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SLEEP APNEA SYNDROME; WORK DISABILITY;

ABSENTEEISM; ADULT; DISABILITY EVALUATION; FEMALE; FINLAND; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PENSIONS; PROSPECTIVE STUDIES; REGISTRIES; RISK ASSESSMENT; RISK FACTORS; SICK LEAVE; SLEEP APNEA, OBSTRUCTIVE; YOUNG ADULT;

EID: 67349182913     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2009.01.014     Document Type: Article

References (53)

1. The international classification of sleep disorders, revised: diagnostic and coding manual (2001), American Academy of Sleep Medicine, Chigaco, Illinois. Available at: [accessed 02.06.08]
2. Cirignotta F., D'Alessandro R., Partinen M., et al. Prevalence of every night snoring and obstructive sleep apnoeas among 30-69-year-old men in Bologna, Italy. Acta Neurol Scand 79 (1989) 366-372
3. Young T., Palta M., Dempsey J., Skatrud J., Weber S., and Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328 (1993) 1230-1235
4. Bearpark H., Elliott L., Grunstein R., et al. Snoring and sleep apnea. A population study in Australian men. Am J Respir Crit Care Med 151 (1995) 1459-1465
5. Young T., Peppard P.E., and Gottlieb D.J. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med 165 (2002) 1217-1239
6. Anttalainen U., Saaresranta T., Kalleinen N., Aittokallio J., Vahlberg T., and Polo O. Gender differences in age and BMI distributions in partial upper airway obstruction during sleep. Respir Physiol Neurobiol 159 (2007) 219-226
7. Bixler E.O., Vgontzas A.N., Lin H.M., et al. Association of hypertension and sleep-disordered breathing. Arch Intern Med 160 (2000) 2289-2295
8. Smith R., Ronald J., Delaive K., Walld R., Manfreda J., and Kryger M.H. What are obstructive sleep apnea patients being treated for prior to this diagnosis?. Chest 121 (2002) 164-172
9. Peker Y., Carlson J., and Hedner J. Increased incidence of coronary artery disease in sleep apnoea: a long-term follow-up. Eur Respir J 28 (2006) 596-602
10. Peppard P.E., Szklo-Coxe M., Hla K.M., and Young T. Longitudinal association of sleep-related breathing disorder and depression. Arch Intern Med 166 (2006) 1709-1715
11. Reichmuth K.J., Austin D., Skatrud J.B., and Young T. Association of sleep apnea and type II diabetes: a population-based study. Am J Respir Crit Care Med 172 (2005) 1590-1595
12. West S.D., Nicoll D.J., and Stradling J.R. Prevalence of obstructive sleep apnoea in men with type 2 diabetes. Thorax 61 (2006) 945-950
13. Marti S., Sampol G., Munoz X., et al. Mortality in severe sleep apnoea/hypopnoea syndrome patients: impact of treatment. Eur Respir J 20 (2002) 1511-1518
14. Lindberg E., Janson C., Svardsudd K., Gislason T., Hetta J., and Boman G. Increased mortality among sleepy snorers: a prospective population based study. Thorax 53 (1998) 631-637
15. Marshall N.S., Wong K.K.H., Liu P.Y., Cullen S.R.J., Knuiman M.W., and Grunstein R.R. Sleep apnoea as an independent risk factor for all-cause mortality: the Busselton Health Study. Sleep 31 (2008) 1079-1085
16. Tarasiuk A., Greenberg-Dotan S., Brin Y.S., Simon T., Tal A., and Reuveni H. Determinants affecting health-care utilization in obstructive sleep apnea syndrome patients. Chest 128 (2005) 1310-1314
17. Wittmann V., and Rodenstein D.O. Health care costs and the sleep apnea syndrome. Sleep Med Rev 8 (2004) 269-279
18. Kapur V., Blough D.K., Sandblom R.E., et al. The medical cost of undiagnosed sleep apnea. Sleep 22 (1999) 749-755
19. Bahammam A., Delaive K., Ronald J., Manfreda J., Roos L., and Kryger M.H. Health care utilization in males with obstructive sleep apnea syndrome two years after diagnosis and treatment. Sleep 22 (1999) 740-747
20. Laitinen L.A., Anttalainen U., Pietinalho A., Hämälainen P., and Koskela K. Sleep apnoea: Finnish National guidelines for prevention and treatment 2002-2012. Respir Med 97 (2003) 337-365
21. Lindberg E., Carter N., Gislason T., and Janson C. Role of snoring and daytime sleepiness in occupational accidents. Am J Respir Crit Care Med 164 (2001) 2031-2035
22. Ulfberg J., Carter N., and Edling C. Sleep-disordered breathing and occupational accidents. Scand J Work Environ Health 26 (2000) 237-242
23. Ulfberg J., Carter N., Talback M., and Edling C. Excessive daytime sleepiness at work and subjective work performance in the general population and among heavy snorers and patients with obstructive sleep apnea. Chest 110 (1996) 659-663
24. Mulgrew A.T., Ryan C.F., Fleetham J.A., et al. The impact of obstructive sleep apnea and daytime sleepiness on work limitation. Sleep Med 9 (2007) 42-53
25. Banno K., Manfreda J., Walld R., Delaive K., and Kryger M.H. Healthcare utilization in women with obstructive sleep apnea syndrome 2 years after diagnosis and treatment. Sleep 29 (2006) 1307-1311
26. Ronald J., Delaive K., Roos L., Manfreda J., Bahammam A., and Kryger M.H. Health care utilization in the 10 years prior to diagnosis in obstructive sleep apnea syndrome patients. Sleep 22 (1999) 225-229
27. Albarrak M., Banno K., Sabbagh A.A., et al. Utilization of healthcare resources in obstructive sleep apnea syndrome: a 5-year follow-up study in men using CPAP. Sleep 28 (2005) 1306-1311
28. Tarasiuk A., Greenberg-Dotan S., Simon-Tuval T., Oksenberg A., and Reuveni H. The effect of obstructive sleep apnea on morbidity and health care utilization of middle-aged and older adults. J Am Geriatr Soc 56 (2008) 247-254
29. Sivertsen B., Overland S., Glozier N., Bjørnvatn B., Mæland J.G., and Mykletun A. The effects of obstructive sleep apnoea syndrome on sick leave and work disability. Eur Respir J (2008 Jul 24) (Epub ahead of print)
30. Kouvonen A., Oksanen T., Vahtera J., et al. Low workplace social capital as a predictor of depression: the Finnish Public Sector Study. Am J Epidemiol 167 (2008) 1143-1151
31. World Health Organization. International classification of diseases, injuries ad causes of death, ninth and tenth revision (1977), WHO, Geneva and 1992
32. Guidelines for ATC classification and DDD assignment (2006), WHO Collaborating Centre for Drug Statistics Methodology, Oslo
33. Allison P.D. Survival analysis using the SAS system: a practical guide (1995), SAS Institute Inc., Cary, NC
34. Mazza S., Pepin J.L., Naegele B., et al. Driving ability in sleep apnoea patients before and after CPAP treatment: evaluation on a road safety platform. Eur Respir J 28 (2006) 1020-1028
35. Horstmann S., Hess C.W., Bassetti C., Gugger M., and Mathis J. Sleepiness-related accidents in sleep apnea patients. Sleep 23 (2000) 383-389
36. Åkerstedt T., Kecklund G., Alfredsson L., and Selen J. Predicting long-term sickness absence from sleep and fatigue. J Sleep Res 16 (2007) 341-345
37. Hemingway H., Vahtera J., Virtanen M., Pentti J., and Kivimäki M. Outcome of stable angina in a working population: the burden of sickness absence. Eur J Cardiovasc Prev Rehabil 14 (2007) 373-379
38. Kivimäki M., Vahtera J., Pentti J., Virtanen M., Elovainio M., and Hemingway H. Increased sickness absence in diabetic employees: what is the role of co-morbid conditions?. Diabet Med 24 (2007) 1043-1048
39. Rytsälä H.J., Melartin T.K., Leskelä U.S., Sokero T.P., Lestelä-Mielonen P.S., and Isometsä E.T. Functional and work disability in major depressive disorder. J Nerv Ment Dis 193 (2005) 189-195
40. Alexopoulos E.C., and Burdorf A. Prognostic factors for respiratory sickness absence and return to work among blue collar workers and office personnel. Occup Environ Med 58 (2001) 246-252
41. Laitinen-Krispijn S., and Bijl R.V. Mental disorders and employee sickness absence: the NEMESIS study. Netherlands Mental Health Survey and Incidence Study. Soc Psychiatry Psychiatr Epidemiol 35 (2000) 71-77
42. Bultmann U., Rugulies R., Lund T., Christensen K.B., Labriola M., and Burr H. Depressive symptoms and the risk of long-term sickness absence: a prospective study among 4747 employees in Denmark. Soc Psychiatry Psychiatr Epidemiol 41 (2006) 875-880
43. Deldin P.J., Phillips L.K., and Thomas R.J. A preliminary study of sleep-disordered breathing in major depressive disorder. Sleep Med 7 (2006) 131-139
44. Baran A.S., and Richert A.C. Obstructive sleep apnea and depression. CNS Spectr 8 (2003) 128-134
45. Klaukka T. The Finnish database on drug utilisation. Nor J Epidemiol 11 (2001) 19-22
46. Pajunen P., Koukkunen H., Ketonen M., et al. The validity of the Finnish hospital discharge register and causes of death register data on coronary heart disease. Eur J Cardiovasc Prev Rehabil 12 (2005) 132-137
47. Fletcher R.W., and Fletzher S.W. Clinical epidemiology. The essentials. 4th ed. (2005), Lippincott Williams & Wilkins, Pennsylvania
48. Young T., Evans L., Finn L., and Palta M. Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women. Sleep 20 (1997) 705-706
49. Kapur V., Strohl K.P., Redline S., Iber C., O'Connor G., and Nieto J. Underdiagnosis of sleep apnea syndrome in U.S. communities. Sleep Breath 6 (2002) 49-54
50. Kronholm E., Härmä M., and Hublin C. Uni ja nukkuminen. Elintavat ja niiden väestöryhmäerot Suomessa Terveys 2000 -tutkimus (In English: Sleep and sleeping). In: Prättälä R., and Paalanen L. (Eds). Health behaviour and its socio-demographic differences in Finland. Health 2000 Survey (2007), Hakapaino Oy, Helsinki Publications of the National Public Health Institute, B2/2007
51. Hagen K.B., Tambs K., and Bjerkedal T. A prospective cohort study of risk factors for disability retirement because of back pain in the general working population. Spine 27 (2002) 1790-1796
52. Kyröläinen H., Häkkinen K., Kautiainen H., Santtila M., Pihlainen K., and Häkkinen A. Physical fitness, BMI and sickness absence in male military personnel. Occup Med (Lond) 58 (2008) 251-256
53. Krokstad S., Johnsen R., and Westin S. Social determinants of disability pension: a 10-year follow-up of 62 000 people in a Norwegian county population. Int J Epidemiol 31 (2002) 1183-1191