Successful combination treatment with bevacizumab, thalidomide and autologous PBSC for severe POEMS syndrome

Bone Marrow Transplantation

Volumn 43, Issue 9, 2009, Pages 739-740

  Ohwada, C ^a   Nakaseko, C ^a   Sakai, S ^a   Takeda, Y ^a   Abe, D ^a   Takeuchi, M ^a   Sakaida, E ^a   Masuda, S ^a   Shimizu, N ^a   Cho, R ^a   Nishimura, M ^a   Kanai, K ^a   Misawa, S ^a   Kuwabara, S ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; IMMUNOGLOBULIN LAMBDA CHAIN; MELPHALAN; THALIDOMIDE; VASCULOTROPIN; VINCRISTINE;

ADULT; ANAMNESIS; ARTICLE; ASCITES; AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; BONE MARROW EXAMINATION; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DISEASE SEVERITY; DRUG EFFICACY; DRUG MEGADOSE; ENGRAFTMENT SYNDROME; HUMAN; LUNG INFILTRATE; MALE; PERICARDIAL EFFUSION; PLEURA EFFUSION; POEMS SYNDROME; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESPIRATORY FAILURE; TREATMENT RESPONSE;

ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COMBINED MODALITY THERAPY; HUMANS; MALE; MIDDLE AGED; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; POEMS SYNDROME; THALIDOMIDE; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 67349179147     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2008.381     Document Type: Article

References (10)

1. Dispenzieri A. POEMS syndrome. Blood Rev 2007; 21: 285-299.
2. Dispenzieri A, Lacy MQ, Hayman SR, Kumar SK, Buadi F, Dingli D et al Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndrome. Eur J Haematol 2008; 80: 397-406.
3. Dispenzieri A, Moreno-Aspitia A, Suarez GA, Lacy MQ, Colon-Otero G, Tefferi A et al. Peripheral blood stem cell transplantation in 16 patients with POEMS syndrome, and a review of the literature. Blood 2004; 104: 3400-3407.
4. Badros A, Porter N, Zimrin A. Bevacizumab therapy for POEMS syndrome. Blood 2005; 106: 1135.
5. Samaras P, Bauer S, Stenner-Liewen F, Steiner R, Zweifel M, Renner C et al. Treatment of POEMS syndrome with bevacizumab. Haematologica 2007; 92: 1438-1439.
6. Kanai K, Kuwabara S, Misawa S, Hattori T. Failure of treatment with anti-VEGF monoclonal antibody for longstanding POEMS syndrome. Intern Med 2007; 46: 311-313.
7. Straume O, Bergheirn J, Ernst P. Bevacizumab therapy for POEMS syndrome. Blood 2006; 107: 4972-4973; author reply 4973-4974.
8. Dietrich PY, Duchosal MA. Bevacizumab therapy before autologous stem-cell transplantation for POEMS syndrome. Ann Oncol 2008; 19: 595.
9. Kuwabara S, Misawa S, Kanai K, Sawai S, Hattori T, Nishimura M et al Thalidomide reduces serum VEGF levels and improves peripheral neuropathy in POEMS syndrome. J Neurol Neurosurg Psychiatry 2008; 79: 1255-1257.
10. Cavo M, Zamagni E, Tosi P, Tacchetti P, Cellini C, Cangini D et al Superiority of thalidomide and dexamethasone over vincristine-doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood 2005; 106: 35-39.