Simultaneous optimal experimental design on dose and sample times

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 36, Issue 2, 2009, Pages 125-145

  Nyberg, Joakim ^a   Karlsson, Mats O ^a   Hooker, Andrew C ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Dose optimization; Optimal design; Pharmacometrics; Simultaneous optimization

Indexed keywords

ARTICLE; CONTROLLED STUDY; DOSE CALCULATION; EXPERIMENTAL DESIGN; MATHEMATICAL MODEL; MATHEMATICAL PARAMETERS; MICHAELIS MENTEN KINETICS; PHARMACODYNAMICS; PHARMACOKINETICS; POPULATION MODEL; PRIORITY JOURNAL; SEQUENTIAL ANALYSIS;

ADMINISTRATION, ORAL; ALGORITHMS; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAVENOUS; MODELS, BIOLOGICAL; MODELS, STATISTICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RESEARCH DESIGN; THEOPHYLLINE; TIME FACTORS;

EID: 67349178277     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-009-9114-z     Document Type: Article

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