Recent developments in the design and synthesis of hybrid molecules basedon aminoquinoline ring and their antiplasmodial evaluation

European Journal of Medicinal Chemistry

Volumn 44, Issue 8, 2009, Pages 3091-3113

  Kouznetsov, Vladimir V ^a   Gómez Barrio, Alicia ^b  

^a UNIVERSIDAD INDUSTRIAL DE SANTANDER   (Colombia)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Aminoquinoline hybrid molecules; Malaria; Synthesis

Indexed keywords

2 TERT BUTYLPRIMAQUINE; 4 AMINOQUINOLINE; 4 ETHYL 5 PENTYLOXYPRIMAQUINE; 8 AMINOQUINOLINE DERIVATIVE; AMINOPYROQUINE; AMINOQUINOLINE DERIVATIVE; CHLOROQUINE; DU 1302; FALCIPAIN 2; ISATIN DERIVATIVE; ISOPENTAQUINE; MEPACRINE; N TERT BUTYLAMODIAQUINE; PAMAQUINE; PENTAQUINE; PLASMEPSIN II; PRIMAQUINE; QUININE; TAFENOQUINE; TEBUQUINE; UNCLASSIFIED DRUG;

AGRANULOCYTOSIS; ANTIMALARIAL ACTIVITY; CINCHONA; CROSS COUPLING REACTION; DIPLOPIA; DIZZINESS; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG HALF LIFE; DRUG MECHANISM; DRUG OVERDOSE; DRUG RESISTANCE; DRUG STRUCTURE; DRUG SYNTHESIS; GAMETOCYTOCIDAL ACTIVITY; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEADACHE; HEPATITIS; HISTORY OF MEDICINE; HUMAN; IC 50; LIVER TOXICITY; MALARIA; MALARIA FALCIPARUM; MINIMUM INHIBITORY CONCENTRATION; NAUSEA; NONHUMAN; OXIDATIVE STRESS; PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE; PLASMODIUM OVALE; PLASMODIUM VIVAX; PRURITUS; R FACTOR; RETINOPATHY; REVIEW; SKRAUP REACTION; SUZUKI MIYAURA CROSS COUPLING REACTION;

AMINOQUINOLINES; ANIMALS; ANTIMALARIALS; DRUG DESIGN; HUMANS; PLASMODIUM;

EID: 67349171068     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.02.024     Document Type: Review

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