Heparin-binding EGF-like growth factor is a potent dilator of terminal mesenteric arterioles

Microvascular Research

Volumn 78, Issue 1, 2009, Pages 78-85

  Zhou, Yu ^a   Brigstock, David ^a   Besner, Gail E ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Arterioles; Endothelin; Heparin binding EGF like growth factor; Intestine; Necrotizing enterocolitis; Vasodilator

Indexed keywords

CALCIUM; ENDOTHELIN 1; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; NITRIC OXIDE SYNTHASE;

ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; ENZYME INHIBITION; FLOW RATE; HEMODYNAMIC MONITORING; HUMAN; HUMAN TISSUE; INTESTINE BLOOD FLOW; INTESTINE PRESSURE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; VASOCONSTRICTION; VASODILATATION;

ANIMALS; ANIMALS, NEWBORN; ARTERIOLES; CALCIUM; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; HEMODYNAMICS; HUMANS; INFANT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTESTINAL MUCOSA; INTESTINES; MALE; MESENTERY; MICROVESSELS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN B; VASOCONSTRICTION; VASODILATION; VASODILATOR AGENTS;

RATTUS; RODENTIA;

EID: 67349164758     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2009.04.006     Document Type: Article

References (53)

1. Abe Y., Nakayama K., Yamanaka A., Sakurai T., and Goto K. Subtype-specific trafficking of endothelin receptors. J. Biol. Chem. 275 (2000) 8664-8671
2. Adams D.J., Barakeh J., Laskey R., and Van Breemen C. Ion channels and regulation of intracellular calcium in vascular endothelial cells. Faseb J. 3 (1989) 2389-2400
3. Adner M., Geary G.G., and Edvinsson L. Appearance of contractile endothelin-B receptors in rat mesenteric arterial segments following organ culture. Acta Physiol. Scand. 163 (1998) 121-129
4. Bates D.O., and Curry F.E. Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway. Am. J. Physiol. 273 (1997) H687-H694
5. Besner G., Higashiyama S., and Klagsbrun M. Isolation and characterization of a macrophage-derived heparin-binding growth factor. Cell Regul. 1 (1990) 811-819
6. Davis K.M., Brigstock D.R., Johnson P.R., Crissman-Combs M.A., McCarthy D.W., Downing M.T., and Besner G.E. Production of glycosylated heparin-binding EGF-like growth factor in HeLa cells using vaccinia virus. Protein Expr. Purif. 8 (1996) 57-67
7. Dawson N.S., Zawieja D.C., Wu M.H., and Granger H.J. Signaling pathways mediating VEGF165-induced calcium transients and membrane depolarization in human endothelial cells. Faseb J. 20 (2006) 991-993
8. El-Assal O.N., and Besner G.E. Heparin-binding epidermal growth factor-like growth factor and intestinal ischemia-reperfusion injury. Semin. Pediatr. Surg. 13 (2004) 2-10
9. El-Assal O.N., and Besner G.E. HB-EGF enhances restitution after intestinal ischemia/reperfusion via PI3K/Akt and MEK/ERK1/2 activation. Gastroenterology 129 (2005) 609-625
10. El-Assal O.N., Radulescu A., and Besner G.E. Heparin-binding EGF-like growth factor preserves mesenteric microcirculatory blood flow and protects against intestinal injury in rats subjected to hemorrhagic shock and resuscitation. Surgery 142 (2007) 234-242
11. Feng J., El-Assal O.N., and Besner G.E. Heparin-binding epidermal growth factor-like growth factor decreases the incidence of necrotizing enterocolitis in neonatal rats. J. Pediatr. Surg. 41 (2006) 144-149 discussion 144-149
12. Higashiyama S., Abraham J.A., Miller J., Fiddes J.C., and Klagsbrun M. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 251 (1991) 936-939
13. Hirata Y., Emori T., Eguchi S., Kanno K., Imai T., Ohta K., and Marumo F. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J. Clin. Invest. 91 (1993) 1367-1373
14. Hsueh W., Caplan M.S., Sun X., Tan X., MacKendrick W., and Gonzalez-Crussi F. Platelet-activating factor, tumor necrosis factor, hypoxia and necrotizing enterocolitis. Acta Paediatr. Suppl. 396 (1994) 11-17
15. Ito Y., Doelle S.M., Clark J.A., Halpern M.D., McCuskey R.S., and Dvorak B. Intestinal microcirculatory dysfunction during the development of experimental necrotizing enterocolitis. Pediatr. Res. 61 (2007) 180-184
16. Jacques D., Sader S., Perreault C., Abdel-Samad D., Jules F., and Provost C. NPY, ET-1, and Ang II nuclear receptors in human endocardial endothelial cells. Can. J. Physiol. Pharmacol. 84 (2006) 299-307
17. Jouneaux C., Goldsmith P., Hanoune J., and Lotersztajn S. Endothelin inhibits the calcium pump and stimulates phosphoinositide phospholipase C in liver plasma membranes via two different G proteins, Gs and Gq. J. Cardiovasc. Pharmacol. 22 Suppl 8 (1993) S158-S160
18. Kliegman R.M., and Fanaroff A.A. Necrotizing enterocolitis. N. Engl. J. Med. 310 (1984) 1093-1103
19. Kuhn M.A., Xia G., Mehta V.B., Glenn S., Michalsky M.P., and Besner G.E. Heparin-binding EGF-like growth factor (HB-EGF) decreases oxygen free radical production in vitro and in vivo. Antioxid. Redox. Signal. 4 (2002) 639-646
20. Lara-Marquez M.L., Mehta V., Michalsky M.P., Fleming J.B., and Besner G.E. Heparin-binding EGF-like growth factor down regulates proinflammatory cytokine-induced nitric oxide and inducible nitric oxide synthase production in intestinal epithelial cells. Nitric Oxide 6 (2002) 142-152
21. Marasciulo F.L., Montagnani M., and Potenza M.A. Endothelin-1: the yin and yang on vascular function. Curr. Med. Chem. 13 (2006) 1655-1665
22. Markel T.A., Crisostomo P.R., Wairiuko G.M., Pitcher J., Tsai B.M., and Meldrum D.R. Cytokines in necrotizing enterocolitis. Shock 25 (2006) 329-337
23. Masaki T., Kimura S., Yanagisawa M., and Goto K. Molecular and cellular mechanism of endothelin regulation. Implications for vascular function. Circulation 84 (1991) 1457-1468
24. Mehta V.B., and Besner G.E. HB-EGF promotes angiogenesis in endothelial cells via PI3-kinase and MAPK signaling pathways. Growth Factors 25 (2007) 253-263
25. Mehta V.B., Zhou Y., Radulescu A., and Besner G.E. HB-EGF stimulates eNOS expression and nitric oxide production and promotes eNOS dependent angiogenesis. Growth Factors 26 (2008) 301-315
26. Nakano D., Pollock J.S., and Pollock D.M. Renal medullary ETB receptors produce diuresis and natriuresis via NOS1. Am. J. Physiol. Renal Physiol. 294 (2008) F1205-F1211
27. Nankervis C.A., and Nowicki P.T. Role of nitric oxide in regulation of vascular resistance in postnatal intestine. Am. J. Physiol. 268 (1995) G949-G958
28. Nankervis C.A., and Nowicki P.T. Role of endothelin-1 in regulation of the postnatal intestinal circulation. Am. J. Physiol. Gastrointest. Liver Physiol. 278 (2000) G367-G375
29. Nankervis C.A., Dunaway D.J., and Nowicki P.T. Determinants of terminal mesenteric artery resistance during the first postnatal month. Am. J. Physiol. Gastrointest. Liver Physiol. 280 (2001) G678-G686
30. Nankervis C.A., Reber K.M., and Nowicki P.T. Age-dependent changes in the postnatal intestinal microcirculation. Microcirculation 8 (2001) 377-387
31. Nankervis C.A., Schauer G.M., and Miller C.E. Endothelin-mediated vasoconstriction in postischemic newborn intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 279 (2000) G683-G691
32. Nankervis C.A., Giannone P.J., and Reber K.M. The neonatal intestinal vasculature: contributing factors to necrotizing enterocolitis. Semin. Perinatol. 32 (2008) 83-91
33. Nilius B., and Droogmans G. Ion channels and their functional role in vascular endothelium. Physiol. Rev. 81 (2001) 1415-1459
34. Nowicki P. Intestinal ischemia and necrotizing enterocolitis. J. Pediatr. 117 (1990) S14-S19
35. Nowicki P.T. The effects of ischemia-reperfusion on endothelial cell function in postnatal intestine. Pediatr. Res. 39 (1996) 267-274
36. Nowicki P.T. Ischemia and necrotizing enterocolitis: where, when, and how. Semin. Pediatr. Surg. 14 (2005) 152-158
37. Nowicki P.T., and Minnich L.A. Effects of systemic hypotension on postnatal intestinal circulation: role of angiotensin. Am. J. Physiol. 276 (1999) G341-G352
38. Nowicki P.T., Dunaway D.J., Nankervis C.A., Giannnone P.J., Reber K.M., Hammond S.B., Besner G.E., and Caniano D.A. Endothelin-1 in human intestine resected for necrotizing enterocolitis. J. Pediatr. 146 (2005) 805-810
39. Ozaki S., Ohwaki K., Ihara M., Fukuroda T., Ishikawa K., and Yano M. ETB-mediated regulation of extracellular levels of endothelin-1 in cultured human endothelial cells. Biochem. Biophys. Res. Commun. 209 (1995) 483-489
40. Pillai S.B., Hinman C.E., Luquette M.H., Nowicki P.T., and Besner G.E. Heparin-binding epidermal growth factor-like growth factor protects rat intestine from ischemia/reperfusion injury. J. Surg. Res. 87 (1999) 225-231
41. Pollock J.S., and Pollock D.M. Endothelin and NOS1/nitric oxide signaling and regulation of sodium homeostasis. Curr. Opin. Nephrol. Hypertens. 17 (2008) 70-75
42. Pollock D.M., Keith T.L., and Highsmith R.F. Endothelin receptors and calcium signaling. Faseb J. 9 (1995) 1196-1204
43. Reber K.M., Nankervis C.A., and Nowicki P.T. Newborn intestinal circulation. Physiology and pathophysiology. Clin. Perinatol. 29 (2002) 23-39
44. Rocourt D.V., Mehta V.B., and Besner G.E. Heparin-binding EGF-like growth factor decreases inflammatory cytokine expression after intestinal ischemia/reperfusion injury. J. Surg. Res. 139 (2007) 269-273
45. Rowe M.I., Reblock K.K., Kurkchubasche A.G., and Healey P.J. Necrotizing enterocolitis in the extremely low birth weight infant. J. Pediatr. Surg 29 (1994) 987-990 discussion 990-981
46. Su B.Y., Reber K.M., Nankervis C.A., and Nowicki P.T. Development of the myogenic response in postnatal intestine: role of PKC. Am. J. Physiol. Gastrointest. Liver Physiol. 284 (2003) G445-G452
47. Tirapelli C.R., Casolari D.A., Yogi A., Montezano A.C., Tostes R.C., Legros E., D'Orleans-Juste P., and de Oliveira A.M. Functional characterization and expression of endothelin receptors in rat carotid artery: involvement of nitric oxide, a vasodilator prostanoid and the opening of K+ channels in ETB-induced relaxation. Br. J. Pharmacol. 146 (2005) 903-912
48. Tiruppathi C., Ahmmed G.U., Vogel S.M., and Malik A.B. Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation 13 (2006) 693-708
49. Unthank J.L., Lash J.M., and Bohlen H.G. Maturation of the rat intestinal microvasculature from juvenile to early adult life. Am. J. Physiol. 259 (1990) G282-G289
50. Vanner S., Jiang M.M., Brooks V.L., and Surprenant A. Characterization of vasopressin actions in isolated submucosal arterioles of the intestinal microcirculation. Circ. Res. 67 (1990) 1017-1026
51. Wu-Wong J.R., Chiou W.J., Magnuson S.R., and Opgenorth T.J. Endothelin receptor in human astrocytoma U373MG cells: binding, dissociation, receptor internalization. J. Pharmacol. Exp. Ther. 274 (1995) 499-507
52. Xia G., Martin A.E., and Besner G.E. Heparin-binding EGF-like growth factor downregulates expression of adhesion molecules and infiltration of inflammatory cells after intestinal ischemia/reperfusion injury. J. Pediatr. Surg. 38 (2003) 434-439
53. Yamamoto K., Korenaga R., Kamiya A., Qi Z., Sokabe M., and Ando J. P2X(4) receptors mediate ATP-induced calcium influx in human vascular endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 279 (2000) H285-H292