Identified biosynthetic pathway of aspergiolide A and a novel strategy to increase its production in a marine-derived fungus Aspergillus glaucus by feeding of biosynthetic precursors and inhibitors simultaneously

Bioresource Technology

Volumn 100, Issue 18, 2009, Pages 4244-4251

  Sun, Xueqian ^a   Zhou, Xiangshan ^a   Cai, Menghao ^a   Tao, Kejing ^a   Zhang, Yuanxing ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Aspergillus glaucus; Aspergiolide A; Pathway specific inhibitor; Polyketide pathway; Precursor

Indexed keywords

ASPERGILLUS GLAUCUS; ASPERGIOLIDE A; PATHWAY SPECIFIC INHIBITOR; POLYKETIDE PATHWAY; PRECURSOR;

KETONES; METABOLITES;

BIOSYNTHESIS;

ACETIC ACID; ACETYL COENZYME A; ADENOSINE DIPHOSPHATE; ANTHRAQUINONE DERIVATIVE; ANTINEOPLASTIC AGENT; ASPERGIOLIDE A; CERULENIN; DIETHYL PYROCARBONATE; EDETIC ACID; IODOACETAMIDE; MEVALONIC ACID; POLYKETIDE; PROPIONIC ACID; SIMVASTATIN; TRIMETHYLAMINE; UNCLASSIFIED DRUG;

ACETATE; BIOTECHNOLOGY; CITRIC ACID; DYE; FUNGUS; INHIBITOR; MARINE TECHNOLOGY; SECONDARY METABOLITE; TUMOR;

ARTICLE; ASPERGILLUS; ASPERGILLUS GLAUCUS; BIOSYNTHESIS; CONTROLLED STUDY; DRUG SYNTHESIS; METABOLITE; NONHUMAN; PRIORITY JOURNAL;

ACETATES; ANTHRAQUINONES; ASPERGILLUS; MARINE BIOLOGY; MEVALONIC ACID; SHIKIMIC ACID; SIMVASTATIN;

ASPERGILLUS GLAUCUS; FUNGI;

EID: 67349157316     PISSN: 09608524     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biortech.2009.03.061     Document Type: Article

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