A drop of hydrogen peroxide can differentiate exudative pleural effusion from transudate - development of a bedside screening test

Clinica Chimica Acta

Volumn 405, Issue 1-2, 2009, Pages 83-86

  Sarkar, Subendu ^a   Bhattacharya, Gorachand ^a   Bhattacharjee, Soumya ^b   Banerjee, Dibyajyoti ^c  

^a CALCUTTA NATIONAL MEDICAL COLLEGE   (India)

^b R G KAR MEDICAL COLLEGE   (India)

^c POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Biomarker; Exudate; Hydrogen peroxide; Oxidative stress; Pleural effusion; Transudate

Indexed keywords

CATALASE; HYDROGEN PEROXIDE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PLEURA EFFUSION; PLEURA FLUID; POINT OF CARE TESTING; PRIORITY JOURNAL; SCHOOL CHILD; SPECTROPHOTOMETRY;

DIAGNOSIS, DIFFERENTIAL; EXUDATES AND TRANSUDATES; HUMANS; HYDROGEN PEROXIDE; MASS SCREENING; OXIDATIVE STRESS; PLEURAL EFFUSION;

EID: 67349151353     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2009.04.004     Document Type: Article

References (23)

1. Paddock F.K. The diagnostic significance of serous fluid in disease. N Engl J Med 223 (1998) 1010-1015
2. Broaddus V.C., and Light R.W. What is the origin of pleural transudates and exudates [editorial]?. Chest 102 (1992) 658
3. Light R.W. Pleural diseases. fifth ed. (2007), Lippincott, Philadelphia
4. Romero-Candeira S., Hernandez L., Romero-Brufao S., Orts D., Fernandez C., and Martin C. Is it meaningful to use biochemical parameters to discriminate between transudative and exudative pleural effusions?. Chest 122 (2002) 1524-1529
5. Leuallel E.C., and Carr D.T. Pleural effusions, a statistical study of 436 patients. N Engl J Med 252 (1955) 79-83
6. Carr D.T., and Power M.H. Clinical value of measurements of concentration of protein in pleural fluid. N Engl J Med 259 (1972) 926-927
7. Light R.W., MacGregor M.I., Luchsinger P.C., et al. Pleural effusions: the diagnostic separation of transudates and exudates. Ann In Tern Med 77 (1972) 507-513
8. Valdes L., Pose A., Suarez J., et al. Cholesterol: a useful parameter for distinguishing between pleural exudates and transudates. Chest 99 (1991) 1097-1102
9. Meisel S., Shamis A., Thaler M., Nussinovitch N., and Rosenthal T. Pleural fluid to serum bilirubin concentration ratio for the separation of transudates from exudates. Chest 98 (1990) 141-144
10. Pachon E.G., Navas I.P., Sanchez J.F., Jimenez B., and Custardoy J. Pleural fluid to serum cholinesterase ratio for the separation of transudates and exudates. Chest 110 (1996) 97-101
11. Yetkin O., Tek I., Kaya A., Ciledag A., and Numanoglu N. A simple laboratory measurement for discrimination of transudative and exudative pleural effusion: pleural viscosity. Respir Med 100 (2006) 1286-1290
12. Nandalur K.R., Hardie A.H., Bollampally S.r., Parmar J.P., and Hagspiel K.D. Accuracy of computed tomography attenuation values in the characterization of pleural fluid: an ROC study. Acad Radiol 12 (2005) 987-991
13. Chan M.H.M., Cow K.M., Chan A.T.C., et al. Quantitative analysis of pleural fluid cell free DNA as a tool for the classification of pleural effusions. Clin Chem 49 (2003) 740-745
14. Porcel M.J., Vives M., Esquerda A., and Rivas C.M. Pleural protein capillary electrophoresis for the separation of transudates and exudates. Clin Chem 47 (2001) 975-976
15. Papageorgiou E., Kostikas K., Kiropoulos T., Karetsi E., Mpatavanis G., and Gourgoulianis K.I. Increased oxidative stress in exudative pleural effusions. Chest 128 (2005) 3291-3297
16. Metintas M., Alatas O., Alatas F., Colak O., Ozdemir N., and Erginel S. Comparative analysis of biochemical parameters for differentiation of pleural exudates from transudates: Light's criteria, cholesterol, bilirubin, albumin gradient, alkaline phosphatase, creatine kinase, and uric acid. Clin Chim Acta 264 (1997) 149-162
17. Mochnik P.A., Frei B., and Ames B.N. Measurement of antioxidants in human blood plasma. In: Packer L. (Ed). Methods in enzymology vol. 234 (1994), Academic Press, San Diego 269-279
18. Yagi K. Assay for blood plasma or serum. In: Packer L. (Ed). Methods in enzymology vol. 105 (1984), Academic Press, San Diego 328-331
19. Nillsson U.A., Bassen M., Savman K., and Kjellmer I. A simple and rapid method for the determination of free iron in biological fluids. Free Radic Res 36 (2002) 677-684
20. Aebi H.E. Catalase. In: Bergmeyer H.U. (Ed). Methods of enzymatic analysis. 3rd edition vol. 3 (1986), VCH Verlagsgesellschaft mbH, Weinheim 273-286
21. Harold V. Practical clinical biochemistry (1969), Interscience Publishers, New York
22. Cragun W.H. Pleural effusion prediction failures. Chest 122 (2002) 1505-1506
23. Rynning M., Wentzel-Larsen T., and Bolann B.J. A model for an uncertainty budget for preanalytical variables in clinical chemistry analyses. Clin Chem 53 (2007) 1343-1348