Non-simultaneous ecotoxicity testing of single chemicals and their mixture results in erroneous conclusions about the joint action of the mixture

Chemosphere

Volumn 76, Issue 3, 2009, Pages 428-432

  De Laender, F ^a,b   Janssen, C R ^b   De Schamphelaere, K A C ^b  

^a NETHERLANDS INSTITUTE OF ECOLOGY NIOO KNAW   (Netherlands)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Concentration addition; Experimental design; Mixture toxicity; Statistical power

Indexed keywords

ADDITIVES; DESIGN OF EXPERIMENTS; TOXICITY;

CONCENTRATION ADDITION; ECOTOXICITY EVALUATION; EXPERIMENTAL ERRORS; FALSE NEGATIVE RATE; FALSE POSITIVE RATES; MIXTURE TOXICITY; SIMULATION STUDIES; STATISTICAL POWER;

BINARY MIXTURES;

ANTAGONISM; CONCENTRATION (COMPOSITION); ECOTOXICOLOGY; EXPERIMENTAL DESIGN; EXPERIMENTAL STUDY; PREDICTION; TOXICITY TEST;

ANALYTICAL ERROR; ARTICLE; CHEMICAL REACTION; ECOTOXICITY; FALSE NEGATIVE RESULT; SIMULATION; TOXICITY TESTING;

EID: 67349145399     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2009.03.027     Document Type: Article

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