Performance of the EU-harmonised mouse bioassay for lipophilic toxins for the detection of azaspiracids in naturally contaminated mussel (Mytilus edulis) hepatopancreas tissue homogenates characterised by liquid chromatography coupled to tandem mass spectrometry

Toxicon

Volumn 53, Issue 7-8, 2009, Pages 713-722

  Hess, Philipp ^a   Butter, Tim ^b   Petersen, Andrew ^b   Silke, Joe ^a   McMahon, Terry ^a  

^a MARINE INSTITUTE   (Ireland)

^b En Force Laboratories Ltd   (Ireland)

Author keywords

Assay performance; Instrument response factor; Lethality; Mass spectrometry; Matrix effects; Phycotoxins; Public safety; Qualitative analysis; Shellfish; Toxic equivalence factor

Indexed keywords

AZASPIRACID;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; EUROPEAN UNION; HEPATOPANCREAS; LC 50; LIQUID CHROMATOGRAPHY; LIVER HOMOGENATE; MATHEMATICAL MODEL; MOUSE BIOASSAY; MUSSEL; NONHUMAN; PERFORMANCE; PRIORITY JOURNAL; SIGMOID; TANDEM MASS SPECTROMETRY; TISSUE HOMOGENATE;

ANIMALS; BIOLOGICAL ASSAY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EUROPEAN UNION; FOOD CONTAMINATION; HEPATOPANCREAS; INDICATORS AND REAGENTS; LIPIDS; MALE; MARINE TOXINS; MICE; MODELS, STATISTICAL; MYTILUS EDULIS; REGRESSION ANALYSIS; SPIRO COMPOUNDS; TANDEM MASS SPECTROMETRY;

MUS; MYTILUS EDULIS;

EID: 67349130765     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.02.015     Document Type: Article

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