Upregulation of ginsenoside and gene expression related to triterpene biosynthesis in ginseng hairy root cultures elicited by methyl jasmonate

Plant Cell, Tissue and Organ Culture

Volumn 98, Issue 1, 2009, Pages 25-33

  Kim, Ok Tae ^a   Bang, Kyong Hwan ^a   Kim, Young Chang ^a   Hyun, Dong Yun ^a   Kim, Min Young ^b   Cha, Seon Woo ^a  

^a Rural Development Administration   (South Korea)

^b Jeonnam Agricultural Research and Extension Service   (South Korea)

Author keywords

Cytochrome P450 depentent hydroxylase; Glucosyltransferase; Methyl jasmonate; Protopanaxadiol; Protopanaxatriol

Indexed keywords

CYTOCHROME P450-DEPENTENT HYDROXYLASE; GLUCOSYLTRANSFERASE; METHYL JASMONATE; PROTOPANAXADIOL; PROTOPANAXATRIOL;

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; BIOSYNTHESIS; ENZYMES; GENES; RUBIDIUM;

TRANSCRIPTION;

PANAX GINSENG;

EID: 67349125738     PISSN: 01676857     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11240-009-9535-9     Document Type: Article

References (33)

1. L Achnine DV Huhman MA Farag LW Sumner JW Blount RA Dixon 2005 Genomic-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula Plant J 41 875 887 10.1111/j.1365-313X.2005.02344.x (Pubitemid 40398716)
2. KH Bae YE Choi CG Shin YY Kim YS Kim 2006 Enhanced ginsenoside productivity by combination of ethephon and methyl jasmonate in ginseng (Panax ginseng C.A. Meyer) adventitious root cultures Biotechnol Lett 28 1163 1166 10.1007/s10529-006-9071-1
3. Bang KH, Kim OT, Jung SJ, Kim YC, Park HW, Cha SW (2009) Molecular characterization of ginseng farnesyl diphosphate synthase gene and its up-regulation by methyl jasmonate. Biol Plant (in press)
4. MM Bradford 1976 A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3
5. DP Briskin 2000 Medicinal plants and phytomedicines. Linking plant biochemistry and physiology to human health Plant Physiol 124 507 514 10.1104/pp.124.2.507 (Pubitemid 30801050)
6. DW Choi JD Jung YI Ha HW Park DS In HJ Chung JR Liu 2005 Analysis of transcripts in methyl jasmonate-treated ginseng hairy roots to identify genes involved in the biosynthesis of ginsenosides and other secondary metabolites Plant Cell Rep 23 557 566 10.1007/s00299-004-0845-4
7. RA Creelman JE Mullet 1997 Biosynthesis and action of jasmonates in plants Annu Rev Plant Physiol Plant Mol Biol 48 355 381 10.1146/annurev.arplant. 48.1.355
8. S Daudonnet F Karst Y Tourte 1997 Expression of the farnesyl diphosphate synthase gene of Saccharomyces cerevisiae in tobacco Mol Breed 3 137 145 10.1023/A:1009685032495 (Pubitemid 127507799)
9. TY Gorpenchenko KV Kiselev VP Bulgakov GK Tchernoded EA 'ragina MV Khodakovskaya OG Koren TB Batygina YN Zhuravlev 2006 The Agrobacterium rhizogenes rolC-gene-induced somatic embryogenesis and shoot organogenesis in Panax ginseng transformed calluses Planta 223 457 467 10.1007/s00425-005-0102-2
10. JY Han YS Kwon DC Yang YR Jung YE Choi 2006 Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng Plant Cell Physiol 47 1653 1662 10.1093/pcp/pcl032
11. FX Hu JJ Zhong 2007 Role of jasmonic acid in alteration of ginsenoside heterogeneity in elicited cell cultures of Panax notoginseng J Biosci Bioeng 104 513 516 10.1263/jbb.104.513
12. FX Hu JJ Zhong 2008 Jasmonic acid mediates gene transcription of ginsenoside biosynthesis in cell cultures of Panax notoginseng treated with chemically synthesized 2-hydroxyethyl jasmonate Process Biochem 43 113 118 10.1016/j.procbio.2007.10.010
13. B Hwang KM Ko 1989 Induction and culture of hairy roots from ginseng (Panax ginseng C.A. Meyer) roots discs by Agrobacterium rhizogenes Korean J Biotechnol Bioeng 4 288 292
14. Y Kaminaga FP Sahin H Mizukami 2004 Molecular cloning and characterization of a glucosyltransferase catalyzing glucosylation of curcumin in cultured Catharanthus roseus cells FEBS Lett 567 197 202 10.1016/j.febslet. 2004.04.056
15. A Kessler IT Baldwin 2002 Plant responses to insect herbivory: the emerging molecular analysis Annu Rev Plant Biol 53 299 328 10.1146/annurev. arplant.53.100301.135207
16. YS Kim EJ Hahn HN Murthy KY Paek 2004 Adventitious root growth and ginsenoside accumulation in Panax ginseng cultures as affected by methyl jasmonate Biotechnol Lett 26 1619 1622 10.1007/s10529-004-3183-2
17. T Kushiro M Shibuya Y Ebizuka 1998 β-amyrin synthase-cloning of oxidosqualene cyclase that catalyzes the formation of the most popular triterpene among higher plants Eur J Biochem 256 238 244 10.1'46/j.1432-1327. 1998.2560238.x
18. MH Lee JH Jeong JW Seo CG Shin YS Kim JG In DC Yang JS Yi YE Choi 2004 Enhanced triterpene and phytosterol biosynthesis in Panax ginseng overexpressing squalene synthase gene Plant Cell Physiol 45 976 984 10.1093/pcp/pch126
19. MB Lu HL Wong WL Teng 2001 Effects of elicitation on the production of saponin in cell culture of Panax ginseng Plant Cell Rep 20 647 677 10.1007/s002990100349
20. XQ Ma XM Liang Q Xu XZ Zhang HB Xiao 2005 Identification of ginsenosides in roots of Panax ginseng by HPLC-APCI/MS Phytochem Anal 16 181 187 10.1002/pca.842
21. D Meesapyodsuk J Balsevich DW Reed PS Covello 2007 Saponin biosynthesis in Saponaria vaccaria. cDNAs encoding β-amyrin synthase and a triterpene carboxylic acid glucosyltransferase Plant Physiol 143 959 969 10.1104/pp.106.088484
22. T Murashige F Skoog 1962 A revised medium for rapid growth and bioassays with tobacco tissue Physiol Plant 15 473 497 10.1111/j.1399-3054.1962.tb08052.x
23. J Palazón RM Cusidó M Bonfill A Mallol E Moyano C Morales MT Piñol 2003 Elicitation of different Panax ginseng transformed root phenotypes for an improved ginsenoside production Plant Physiol Biochem 41 1019 1025 10.1016/j.plaphy.2003.09.002
24. L Pauwels K Morreel ED Witte F Lammertyn MV Montagu W Boerjan D Inźe A Goossens 2008 Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells Proc Natl Acad Sci USA 105 1380 1385 10.1073/pnas.0711203105
25. S Shibata 2001 Chemistry and cancer preventing activities of ginseng saponins and some related triterpenoid compounds J Korean Med Sci 16 S28 S37
26. M Shibuya M Hoshino Y Katsube H Hayashi T Kushiro Y Ebizuka 2006 Identification of β-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay FEBS J 273 948 959 10.1111/j.1742-4658.2006.05120.x
27. O Sticher 1998 Getting to the root of ginseng Chemtech 28 26 32 (Pubitemid 128545321)
28. H Suzuki L Achnine R Xu SPT Matsuda RA Dixon 2002 A genomic approach to the early stages of triterpene saponin biosynthesis in Medicago truncatula Plant J 32 1033 1048 10.1046/j.1365-313X.2002.01497.x
29. P Tansakul M Shibuya T Kushiro Y Ebizuka 2006 Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng FEBS Lett 580 5143 5149 10.1016/j.febslet.2006.08.044
30. W Wang ZJ Zhao Y Xu X Qian JJ Zhong 2006 Efficient induction of ginsenoside biosynthesis and alteration of ginsenoside heterogeneity in cell cultures of Panax notoginseng by using chemically synthesized 2-hyroxylethyl jasmonate Appl Microbiol Biotechnol 70 298 307 10.1007/s00253-005-0089-4
31. KW Yu W Gao EJ Hahn KY Paek 2002 Jasmonic acid improves ginsenoside accumulation in adventitious root culture of Panax ginseng C.A. Meyer Biochem Eng J 11 211 215 10.1016/S1369-703X(02)00029-3
32. CJ Yue JJ Zhong 2005 Purification and characterization of UDPG:ginsenoside Rd glucosyltransferase from suspend cells of Panax notoginseng Process Biochem 40 3742 3748 10.1016/j.procbio.2005.05.001
33. CJ Yue X Zhou JJ Zhong 2008 Protopanaxadiol 6-hydroxylase and its role in regulating the ginsenoside heterogeneity in Panax notoginseng cells Biotechnol Bioeng 100 933 940 10.1002/bit.21829