Altered adhesion molecules expression on peripheral blood mononuclear cells from patients with systemic sclerosis and clinical correlations

Clinical Rheumatology

Volumn 28, Issue 7, 2009, Pages 847-851

  Sawaya, Heloisa Helena Braga ^a   de Souza, Romy Beatriz Christmann ^b   Carrasco, Solange ^b   Goldenstein Schainberg, Claudia ^b  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Adhesion molecules; ICAM 1; ICAM 3; Pathogenesis; Scleroderma; Systemic sclerosis

Indexed keywords

CELL ADHESION MOLECULE; CENTROMERE ANTIBODY; IMMUNOSUPPRESSIVE AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 3; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1 ALPHA; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1 BETA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL DAMAGE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSE SYSTEMIC SCLEROSIS; DISEASE DURATION; FEMALE; HUMAN; HUMAN CELL; LIMITED SYSTEMIC SCLEROSIS; MALE; MULTIDRUG TREATMENT THERAPY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; RISK FACTOR; SCLERODERMA; SYSTEMIC SCLEROSIS; THERAPY;

ADULT; ANTIGENS, CD; CELL ADHESION MOLECULES; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERCELLULAR ADHESION MOLECULE-1; L-SELECTIN; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MALE; MIDDLE AGED; SCLERODERMA, SYSTEMIC;

EID: 67349124986     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10067-009-1124-0     Document Type: Article

References (26)

1. Pigot R, Power C (1993) The adhesion molecule facts book. Academic, San Diego
2. Ley K, Tedder TF (1995) Leukocyte interactions with vascular endothelium. New insights into selectin-mediated attachment and rolling. J Immunol 155:525-528
3. Ihn H, Fujimoto M, Sato S, Kikuchi K, Igarashi A, Soma Y et al (1994) Increased levels of circulation intercellular adhesion molecule-1 in patients with localized scleroderma. J Am Acad Dermatol 31:591-595
4. Ihn H, Sato S, Kikuchi K, Fujimoto M, Takehara K (1995) Demonstration of interleukin-2, interleukin-4, and interleukin-6 in sera from patients with localized scleroderma. Arch Dermatol Res 287:193-197
5. Ihn H, Sato S, Kikuchi K, Fujimoto M, Takehara K (1994) Demonstration of interleukin-8 in serum samples of patients with localized scleroderma. Arch Dermatol 130:1327-1328
6. Hasegawa M, Sato T, Takehara K (1999) Augmented production of chemokines (MCP-1, MIP-1α, and MIP-1β) in patients with systemic sclerosis: MCP-1 and MIP-1α may be involved in the development of pulmonary fibrosis. Clin Exp Immunol 117:503-507
7. Solberg S, Peltonen J, Uitto J, Jimenez SA (1992) Elevated expression of beta 1 and beta 2 integrins, intercellular adhesion molecule 1, and endothelial leukocyte adhesion molecule 1 in the skin of patients with systemic sclerosis of recent onset. Arthritis Rheum 35:290-298
8. Gruschwitz MS, Hornstein OP, von den Driesch P (1995) Correlation of soluble adhesion molecules in the peripheral blood of scleroderma patients with their in situ expression and with disease activity. Arthritis Rheum 38:184-189
9. Gruschwitz MS, Hornstein OP, von den Driesch P et al (1992) Expression of adhesion proteins involved in cell-cell and cell-matrix interactions in the skin of patients with progressive systemic sclerosis. J Am Acad Dermatol 27:169-177
10. Majewski S, Hunzelmann N, Johnson JP et al (1991) Expression of intercellular adhesion molecule-1 (ICAM-1) in the skin of patients with systemic scleroderma. J Invest Dermatol 97:667-671
11. Shi-Wen X, Panesar M, Vancheeswaran R et al (1994) Expression and shedding of intercellular adhesion molecule1 and lymphocyte function-associated antigen 3 by normal and scleroderma fibroblasts. Arthritis Rheum 37:1689-1697
12. Shimada Y, Hasegawa M, Takehara K, Sato S (2001) Elevated serum l -selectin levels and decreased l -selectin expression on CD8+ lymphocytes in systemic sclerosis. Clin Exp Immunol 124:474-479
13. Ates A, Kinikli G, Turgay M, Duman M (2004) Serum-soluble selectin levels in patients with rheumatoid arthritis and systemic sclerosis. Scand J Immunol 59:315-320
14. Kuryliszyn-Moskal A, Klimiuk PA, Sierakowski S (2005) Soluble adhesion molecules (sVCAM-1, sE-selectin), vascular endothelial growth factor (VEGF) and endothelin-1 in patients with systemic sclerosis: relationship to organ systemic involvement. Clin Rheumatol 24:111-116
15. Masi AT, Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee (1980) Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 23(5):581-590
16. LeRoy EC, Black C, Fleischmajer R, Jablonska S, Krieg T, Medsger TA Jr, Rowell N, Wollheim F (1988) Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 15(2):202-205
17. Böyum A (1968) Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl 97:77-89
18. Mitri GM, Lucas M, Fertig N, Steen VD, Medsger TA Jr (2003) A comparison between anti-Th/To- and anticentromere antibody-positive systemic sclerosis patients with limited cutaneous involvement. Arthritis Rheum 48(1):203-209
19. Ihn H, Sato S, Fujimoto M, Kikuchi K, Kadono T, Tamaki K, Takahera K (1997) Circulating intercellular adhesion molecule-1 in the sera of patients with systemic sclerosis: Enhancement by inflammatory cytokines. Br J Rheumatol 36:1270-1275
20. Moffatt OD, Devitt A, Bell ED, Simmons DL, Gregory CD (1999) Macrophage recognition of ICAM-3 on apoptotic leukocytes. J Immunol 162:800-810
21. De Fougerolles AR, Springer TA (1992) Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J Exp Med 175:185-190
22. De Fougerolles AR, Diamond MS, Springer TA (1993) Cloning and expression of intercellular adhesion molecule 3 reveals strong homology to other immunoglobulin family counter-receptors for lymphocyte function-associated antigen. J Exp Med 177:1187-1192
23. Walcheck B, Kahn J, Fisher JM, Wang BB, Fisk RS, Payan DG, Feehan C, Betageri R, Darlak K, Spatola AF, Kishimoto TK (1996) Neutrophil rolling altered by inhibition of L-selectin shedding in vitro. Nature 380:720-723
24. Chen A, Engel P, Tedder TF (1995) Structural requirements regulate endoproteolytic release of the L-selectin (CD62L) adhesion receptor from the cell surface of leukocytes. J Exp Med 182:519-530
25. Blann AD, Sanders PA, Herrick A, Jayson MI (1996) Soluble L-selectin in the connective tissue diseases. Br J Haematol 95:192-194
26. Nicolls MR, Gill RG (2006) LFA-1 (CD11a) as a therapeutic target. Am J Transplant 6:26-36