Individual differences in personality traits reflect structural variance in specific brain regions

Brain Research Bulletin

Volumn 79, Issue 5, 2009, Pages 265-270

  Gardini, Simona ^a,b   Cloninger, C Robert ^c   Venneri, Annalena ^b,d  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF HULL   (United Kingdom)

^c WASHINGTON UNIVERSITY   (United States)

^d UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Brain; Grey matter; MRI; Personality; TPQ; Voxel based morphometry

Indexed keywords

ADULT; ARTICLE; BRAIN SIZE; CAUDATE NUCLEUS; FEMALE; FRONTAL CORTEX; GRAY MATTER; HUMAN; IMAGE ANALYSIS; IMAGE DISPLAY; MALE; NEUROANATOMY; NUCLEAR MAGNETIC RESONANCE IMAGING; PERSONALITY; PRIORITY JOURNAL; PSYCHOLOGIC TEST;

ADULT; BRAIN; CEREBRAL CORTEX; EXPLORATORY BEHAVIOR; FEMALE; HARM REDUCTION; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NERVE FIBERS, UNMYELINATED; PERSONALITY; PERSONALITY TESTS; REWARD;

EID: 67349119220     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2009.03.005     Document Type: Article

References (47)

1. Afifi A.K. The basal ganglia: a neural network with more than motor function. Semin. Pediatr. Neurol. 10 (2003) 3-10
2. Aron A., Fisher H., Mashek D.J., Strong G., Li H., and Brown L.L. Reward, motivation, and emotion systems associated with early-stage intense romantic love. J. Neurophysiol. 94 (2005) 327-337
3. Bragulat V., Paillere-Martinot M.L., Artiges E., Frouin V., Poline J.B., and Martinot J.L. Dopaminergic function in depressed patients with affective flattening or with impulsivity: [18F]fluoro-L-dopa positron emission tomography study with voxel-based analysis. Psychiatry Res. 154 (2007) 115-124
4. Broussolle E., Dentresangle C., Landais P., Garcia-Larrea L., Pollak P., Croisile B., Hibert O., Bonnefoi F., Galy G., Froment J.C., and Comar D. The relation of putamen and caudate nucleus 18F-Dopa uptake to motor and cognitive performances in Parkinson's disease. J. Neurol. Sci. 166 (1999) 141-151
5. Bruen P.D., McGeown W.J., Shanks M.F., and Venneri A. Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease. Brain 131 (2008) 2455-2463
6. Cavanna A.E., and Trimble M.R. The precuneus: a review of its functional anatomy and behavioural correlates. Brain 129 (2006) 564-583
7. Cloninger C.R. Feeling Good: The Science of Well Being (2004), Oxford University Press, New York
8. Cloninger C.R. A systematic method for clinical description and classification of personality variants. A proposal. Arch. Gen. Psychiatry 44 (1987) 573-588
9. Cloninger C.R. A unified biosocial theory of personality and its role in the development of anxiety states. Psychiatr. Dev. 4 (1986) 167-226
10. Cloninger C.R., Svrakic D.M., and Przybeck T.R. A psychobiological model of temperament and character. Arch. Gen. Psychiatry 50 (1993) 975-990
11. Comings D.E., Gade-Andavolu R., Gonzalez N., Wu S., Muhleman D., Blake H., Mann M.B., Dietz G., Saucier G., and MacMurray J.P. A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory. Clin. Genet. 58 (2000) 375-385
12. Conway K.P., Kane R.J., Ball S.A., Poling J.C., and Rounsaville B.J. Personality, substance of choice, and polysubstance involvement among substance dependent patients. Drug Alcohol Depend. 71 (2003) 65-75
13. de Fockert J., Rees G., Frith C., and Lavie N. Neural correlates of attentional capture in visual search. J. Cogn. Neurosci. 16 (2004) 751-759
14. Deckersbach T., Miller K.K., Klibanski A., Fischman A., Dougherty D.D., Blais M.A., Herzog D.B., and Rauch S.L. Regional cerebral brain metabolism correlates of neuroticism and extraversion. Depress. Anxiety 23 (2006) 133-138
15. Deiber M.P., Passingham R.E., Colebatch J.G., Friston K.J., Nixon P.D., and Frackowiak R.S. Cortical areas and the selection of movement: a study with positron emission tomography. Exp. Brain Res. 84 (1991) 393-402
16. den Ouden H.E., Frith U., Frith C., and Blakemore S.J. Thinking about intentions. Neuroimage 28 (2005) 787-796
17. Fresan A., Apiquian R., Nicolini H., and Cervantes J.J. Temperament and character in violent schizophrenic patients. Schizophr. Res. 94 (2007) 74-80
18. Gerra G., Zaimovic A., Timpano M., Zambelli U., Begarani M., Marzocchi G.F., Ferri M., Delsignore R., and Brambilla F. Neuroendocrine correlates of temperament traits in abstinent opiate addicts. J. Subst. Abuse 11 (2000) 337-354
19. Grosbras M.H., and Paus T. Transcranial magnetic stimulation of the human frontal eye field: effects on visual perception and attention. J. Cogn. Neurosci. 14 (2002) 1109-1120
20. Gusnard D.A., Ollinger J.M., Shulman G.L., Cloninger C.R., Price J.L., Van Essen D.C., and Raichle M.E. Persistence and brain circuitry. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 3479-3484
21. Hajek T., Carrey N., and Alda M. Neuroanatomical abnormalities as risk factors for bipolar disorder. Bipolar Disord. 7 (2005) 393-403
22. Hakamata Y., Iwase M., Iwata H., Kobayashi T., Tamaki T., Nishio M., Kawahara K., Matsuda H., Ozaki N., Honjo S., and Inada T. Regional brain cerebral glucose metabolism and temperament: a positron emission tomography study. Neurosci. Lett. 396 (2006) 33-37
23. Heiman N., Stallings M.C., Young S.E., and Hewitt J.K. Investigating the genetic and environmental structure of Cloninger's personality dimensions in adolescence. Twin Res. 7 (2004) 462-470
24. Iversen S.D., and Iversen L.L. Dopamine: 50 years in perspective. Trends Neurosci. 30 (2007) 188-193
25. Johnson D.L., Wiebe J.S., Gold S.M., Andreasen N.C., Hichwa R.D., Watkins G.L., and Boles Ponto L.L. Cerebral blood flow and personality: a positron emission tomography study. Am. J. Psychiatry 156 (1999) 252-257
26. Kashdan T.B., and Hofmann S.G. The high-novelty-seeking, impulsive subtype of generalized social anxiety disorder. Depress. Anxiety 25 (2008) 535-541
27. Kim S.J., Kim Y.S., Lee H.S., Kim S.Y., and Kim C.H. An interaction between the serotonin transporter promoter region and dopamine transporter polymorphisms contributes to harm avoidance and reward dependence traits in normal healthy subjects. J. Neural Transm. 113 (2006) 877-886
28. Kincade J.M., Abrams R.A., Astafiev S.V., Shulman G.L., and Corbetta M. An event-related functional magnetic resonance imaging study of voluntary and stimulus-driven orienting of attention. J. Neurosci. 25 (2005) 4593-4604
29. Kircher T.T., Brammer M., Bullmore E., Simmons A., Bartels M., and David A.S. The neural correlates of intentional and incidental self processing. Neuropsychologia 40 (2002) 683-692
30. Kircher T.T., Senior C., Phillips M.L., Benson P.J., Bullmore E.T., Brammer M., Simmons A., Williams S.C., Bartels M., and David A.S. Towards a functional neuroanatomy of self processing: effects of faces and words. Brain Res. Cogn. Brain Res. 10 (2000) 133-144
31. Loftus S.T., Garno J.L., Jaeger J., and Malhotra A.K. Temperament and character dimensions in bipolar I disorder: a comparison to healthy controls. J. Psychiatr. Res. 42 (2008) 1131-1136
32. Martinotti G., Andreoli S., Giametta E., Poli V., Bria P., and Janiri L. The dimensional assessment of personality in pathologic and social gamblers: the role of novelty seeking and self-transcendence. Compr. Psychiatry 47 (2006) 350-356
33. Miki A., Nakajima T., Miyauchi S., Takagi M., and Abe H. Functional magnetic resonance imaging of the frontal eye fields during saccadic eye movements. Nippon Ganka Gakkai Zasshi 100 (1996) 541-545
34. Ono Y., Ando J., Onoda N., Yoshimura K., Momose T., Hirano M., and Kanba S. Dimensions of temperament as vulnerability factors in depression. Mol. Psychiatry 7 (2002) 948-953
35. Pompili M., Rihmer Z., Akiskal H.S., Innamorati M., Iliceto P., Akiskal K.K., Lester D., Narciso V., Ferracuti S., Tatarelli R., De Pisa E., and Girardi P. Temperament and personality dimensions in suicidal and nonsuicidal psychiatric inpatients. Psychopathology 41 (2008) 313-321
36. Roland P.E., Larsen B., Lassen N.A., and Skinhoj E. Supplementary motor area and other cortical areas in organization of voluntary movements in man. J. Neurophysiol. 43 (1980) 118-136
37. Saudino K.J. Behavioral genetics and child temperament. J. Dev. Behav. Pediatr. 26 (2005) 214-223
38. Scott D.J., Heitzeg M.M., Koeppe R.A., Stohler C.S., and Zubieta J.K. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. J. Neurosci. 26 (2006) 10789-10795
39. Sinha R., Lacadie C., Skudlarski P., and Wexler B.E. Neural circuits underlying emotional distress in humans. Ann. N Y Acad. Sci. 1032 (2004) 254-257
40. Sugiura M., Kawashima R., Nakagawa M., Okada K., Sato T., Goto R., Sato K., Ono S., Schormann T., Zilles K., and Fukuda H. Correlation between human personality and neural activity in cerebral cortex. Neuroimage 11 (2000) 541-546
41. Tyler L.K., Marslen-Wilson W., and Stamatakis E.A. Dissociating neuro-cognitive component processes: voxel-based correlational methodology. Neuropsychologia 43 (2005) 771-778
42. Venneri A., McGeown W.J., Hietanen H.M., Guerrini C., Ellis A.W., and Shanks M.F. The anatomical bases of semantic retrieval deficits in early Alzheimer's disease. Neuropsychologia 46 (2008) 497-510
43. Volkow N.D., Wang G.J., Fowler J.S., Logan J., Jayne M., Franceschi D., Wong C., Gatley S.J., Gifford A.N., Ding Y.S., and Pappas N. "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse 44 (2002) 175-180
44. Wellington T.M., Semrud-Clikeman M., Gregory A.L., Murphy J.M., and Lancaster J.L. Magnetic resonance imaging volumetric analysis of the putamen in children with ADHD: combined type versus control. J. Atten. Disord. 10 (2006) 171-180
45. Yamasue H., Abe O., Suga M., Yamada H., Inoue H., Tochigi M., Rogers M., Aoki S., Kato N., and Kasai K. Gender-common and -specific neuroanatomical basis of human anxiety-related personality traits. Cereb. Cortex 18 (2008) 46-52
46. Youn T., Lyoo I.K., Kim J.K., Park H.J., Ha K.S., Lee D.S., Abrams K.Y., Lee M.C., and Kwon J.S. Relationship between personality trait and regional cerebral glucose metabolism assessed with positron emission tomography. Biol. Psychol. 60 (2002) 109-120
47. Zamboni G., Huey E.D., Krueger F., Nichelli P.F., and Grafman J. Apathy and disinhibition in frontotemporal dementia: insights into their neural correlates. Neurology 71 (2008) 736-742