Analysis of the methylation profiles in imprinted genes applicable to parental allele discrimination

Legal Medicine

Volumn 11, Issue SUPPL. 1, 2009, Pages

  Nakayashiki, Nori ^a   Takamiya, Masataka ^a   Shimamoto, Kirito ^a   Aoki, Yasuhiro ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Bisulfite sequencing; Differentially methylated region; Genomic imprinting; Parent of origin

Indexed keywords

GENOMIC DNA;

ALLELE; ARTICLE; AUTOPSY; BLOOD SAMPLING; FORENSIC GENETICS; GENE SEQUENCE; HAIR; HUMAN; HUMAN TISSUE; METHYLATION; NAIL; SALIVA; SINGLE NUCLEOTIDE POLYMORPHISM; SPERM; TESTIS;

ALLELES; BLOOD; BLOOD STAINS; DNA METHYLATION; GENOMIC IMPRINTING; HAIR; HUMANS; LIVER; LUNG; MALE; NAILS; POLYMORPHISM, SINGLE NUCLEOTIDE; SALIVA; SEMEN; SEQUENCE ANALYSIS, DNA; SULFITES; TESTIS;

EID: 67349117317     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.legalmed.2009.02.013     Document Type: Article

References (5)

1. Naito E., Dewa K., Fukuda M., Sumi H., Wakabayashi Y., Umetsu K., et al. Novel paternity testing by distinguishing parental alleles at a VNTR locus in the differentially methylated region upstream of the human H19 gene. J Forensic Sci 48 (2003) 1275-1279
2. Xu H.D., Naito E., Dewa K., Fukuda M., Sumi H., Yuasa I., et al. Parentally imprinted allele typing at a short tandem repeat locus in intron 1a of imprinted gene KCNQ1. Legal Med 8 (2006) 139-143
3. Zhao G., Yang Q., Huang D., Yu C., Yang R., Chen H., et al. Study on the application of parent-of-origin specific DNA methylation markers to forensic genetics. Forensic Sci Int 154 (2005) 122-127
4. Nakayashiki N., Kanetake J., and Aoki Y. A parent-of-origin detectable polymorphism in the hypermethylated region upstream of the human H19 gene. Int J Legal Med 118 (2004) 158-162
5. Nakayashiki N, Takamiya M, Shimamoto K, Aoki Y, Hashiyada M. Studies on differentially methylated parental allele in imprinted genes. Forensic Sci Int 2008;Genetics Supplement Series 1:572-3.