Visceral adipose tissue, adiponectin levels and insulin resistance are related to atherosclerosis as assessed by whole-body magnetic resonance angiography in an elderly population

Atherosclerosis

Volumn 205, Issue 1, 2009, Pages 163-167

  Hansen, T ^a   Ahlstrom H ^a   Soderberg S ^b   Hulthe, J ^c   Wikstrom J ^a   Lind, L ^a   Johansson, L ^c  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Angiography; Atherosclerosis; Magnetic resonance imaging; Obesity; Risk factors

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; C REACTIVE PROTEIN; LEPTIN;

ABDOMINAL OBESITY; AGED; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BODY MASS; CARDIOVASCULAR RISK; DISEASE SEVERITY; FEMALE; HORMONE BLOOD LEVEL; HUMAN; INFLAMMATION; INSULIN RESISTANCE; INTRAABDOMINAL FAT; MAGNETIC RESONANCE ANGIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SUBCUTANEOUS FAT; WHOLE BODY IMAGING;

EID: 67349107196     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2008.11.007     Document Type: Article

References (29)

1. Lilja M., Eliasson M., Stegmayr B., Olsson T., and Soderberg S. Trends in obesity and its distribution: data from the Northern Sweden MONICA Survey, 1986-2004. Obesity (Silver Spring) (2008)
2. Yusuf S., Hawken S., Ounpuu S., et al. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 366 (2005) 1640-1649
3. Nicklas B.J., Penninx B.W., Cesari M., et al. Association of visceral adipose tissue with incident myocardial infarction in older men and women: the health, aging and body composition study. Am J Epidemiol 160 (2004) 741-749
4. Fujimoto W.Y., Bergstrom R.W., Boyko E.J., et al. Visceral adiposity and incident coronary heart disease in Japanese-American men. The 10-year follow-up results of the Seattle Japanese-American Community Diabetes Study. Diabetes Care 22 (1999) 1808-1812
5. Kuk J.L., Katzmarzyk P.T., Nichaman M.Z., Church T.S., Blair S.N., and Ross R. Visceral fat is an independent predictor of all-cause mortality in men. Obesity (Silver Spring) 14 (2006) 336-341
6. Goodpaster B.H., Krishnaswami S., Harris T.B., et al. Obesity, regional body fat distribution, and the metabolic syndrome in older men and women. Arch Intern Med 165 (2005) 777-783
7. Sowers J.R. Obesity as a cardiovascular risk factor. Am J Med 115 Suppl. 8A (2003) 37S-41S
8. Nilsson P.M., Engstrom G., Hedblad B., et al. Plasma adiponectin levels in relation to carotid intima media thickness and markers of insulin resistance. Arterioscler Thromb Vasc Biol 26 (2006) 2758-2762
9. Kumada M., Kihara S., Sumitsuji S., et al. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 23 (2003) 85-89
10. Steffes M.W., Gross M.D., Lee D.H., Schreiner P.J., and Jacobs Jr. D.R. Adiponectin, visceral fat, oxidative stress, and early macrovascular disease: the Coronary Artery Risk Development in Young Adults Study. Obesity (Silver Spring) 14 (2006) 319-326
11. Pischon T., Girman C.J., Hotamisligil G.S., Rifai N., Hu F.B., and Rimm E.B. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 291 (2004) 1730-1737
12. Soderberg S., Stegmayr B., Stenlund H., et al. Leptin, but not adiponectin, predicts stroke in males. J Intern Med 256 (2004) 128-136
13. Margetic S., Gazzola C., Pegg G.G., and Hill R.A. Leptin: a review of its peripheral actions and interactions. Int J Obes Relat Metab Disord 26 (2002) 1407-1433
14. Wolk R., and Somers V.K. Leptin and vascular function: Friend or foe?. Eur Heart J 27 (2006) 2263-2265
15. Beltowski J. Leptin and atherosclerosis. Atherosclerosis 189 (2006) 47-60
16. Goyen M., Quick H.H., Debatin J.F., et al. Whole-body three-dimensional MR angiography with a rolling table platform: initial clinical experience. Radiology 224 (2002) 270-277
17. Lind L., Fors N., Hall J., Marttala K., and Stenborg A. A comparison of three different methods to evaluate endothelium-dependent vasodilation in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Arterioscler Thromb Vasc Biol 25 (2005) 2368-2375
18. Hansen T., Wikstrom J., Johansson L.O., Lind L., and Ahlstrom H. The prevalence and quantification of atherosclerosis in an elderly population assessed by whole-body magnetic resonance angiography. Arterioscler Thromb Vasc Biol 27 (2007) 649-654
19. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
20. Matsuzawa Y., Funahashi T., Kihara S., and Shimomura I. Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol 24 (2004) 29-33
21. Altinova A.E., Toruner F., Bukan N., et al. Decreased plasma adiponectin is associated with insulin resistance and HDL cholesterol in overweight subjects. Endocr J 54 (2007) 221-226
22. Soderberg S., Ahren B., Jansson J.H., et al. Leptin is associated with increased risk of myocardial infarction. J Intern Med 246 (1999) 409-418
23. Ciccone M., Vettor R., Pannacciulli N., et al. Plasma leptin is independently associated with the intima-media thickness of the common carotid artery. Int J Obes Relat Metab Disord 25 (2001) 805-810
24. Rutter M.K., Meigs J.B., Sullivan L.M., D'Agostino Sr. R.B., and Wilson P.W. C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 110 (2004) 380-385
25. Khera A., de Lemos J.A., Peshock R.M., et al. Relationship between C-reactive protein and subclinical atherosclerosis: the Dallas Heart Study. Circulation 113 (2006) 38-43
26. Lo J., Dolan S.E., Kanter J.R., et al. Effects of obesity, body composition, and adiponectin on carotid intima-media thickness in healthy women. J Clin Endocrinol Metab 91 (2006) 1677-1682
27. Lind L., Johansson L., Hulthe J., von Below C., and Ahlstrom H. Vasodilation and visceral fat in elderly subjects. The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Atherosclerosis (2006)
28. Shen W., Punyanitya M., Chen J., et al. Visceral adipose tissue: relationships between single slice areas at different locations and obesity-related health risks. Int J Obes (Lond) (2006)
29. Lee S., Janssen I., and Ross R. Interindividual variation in abdominal subcutaneous and visceral adipose tissue: influence of measurement site. J Appl Physiol 97 (2004) 948-954