Characteristics and mortality of type 2 diabetic patients hospitalized for severe iatrogenic hypoglycemia

Diabetes Research and Clinical Practice

Volumn 84, Issue 3, 2009, Pages 267-272

  Fadini, Gian Paolo ^a   Rigato, Mauro ^a   Tiengo, Antonio ^a   Avogaro, Angelo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Diabetes; Hypoglycemia; Morbidity; Mortality

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CENTRAL DEPRESSANT AGENT; CIMETIDINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; GLUCOSE; INSULIN; INSULIN DERIVATIVE; METFORMIN; NONSTEROID ANTIINFLAMMATORY AGENT; ORAL ANTIDIABETIC AGENT; REPAGLINIDE;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTERY DISEASE; ARTICLE; BLOOD SAMPLING; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; CORONARY ARTERY DISEASE; DEMENTIA; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DISEASE DURATION; DRUG USE; DYSLIPIDEMIA; FALLING; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HOSPITAL PATIENT; HUMAN; HUMAN TISSUE; HYPERTENSION; HYPOGLYCEMIA; HYPOGLYCEMIC COMA; IATROGENIC DISEASE; INSULIN TREATMENT; LENGTH OF STAY; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PROGNOSIS; RETROSPECTIVE STUDY; RHEUMATOID ARTHRITIS; RISK FACTOR;

ADMINISTRATION, ORAL; AGED; AGED, 80 AND OVER; COMORBIDITY; CREATININE; DIABETES MELLITUS, TYPE 2; FEMALE; GLOMERULAR FILTRATION RATE; HOSPITALIZATION; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; IATROGENIC DISEASE; INPATIENTS; INSULIN; MALE; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 67349107195     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2009.01.019     Document Type: Article

References (25)

1. Cryer P.E. Severe iatrogenic hypoglycemia in type 2 diabetes mellitus. Nat. Clin. Pract. Endocrinol. Metab. 3 (2007) 4-5
2. Holstein A., Plaschke A., and Egberts E.H. Incidence and costs of severe hypoglycemia. Diabetes Care 25 (2002) 2109-2110
3. Desouza C., Salazar H., Cheong B., Murgo J., and Fonseca V. Association of hypoglycemia and cardiac ischemia: a study based on continuous monitoring. Diabetes Care 26 (2003) 1485-1489
4. UPDS. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352 (1998) 837-853
5. The absence of a glycemic threshold for the development of long-term complications: the perspective of the Diabetes Control and Complications Trial. Diabetes 45 (1996) 1289-1298
6. Brown A.F., Mangione C.M., Saliba D., Sarkistan C.A., California Healthcare Foundation/American Geriatric Society, and Panel on Improving Care for Elders with Diabetes. Guidelines for improving the care of the older person with diabetes mellitus. J. Am. Geriatr. Soc. 51 (2003) S265-820
7. Clinical Guidelines for Type 2 Diabetes Mellitus European Union Geriatric Medicine Society, http://www.eugms.org/documents/clinicalguidelinediabetes.pdf.
8. Kaufman F.R., Austin J., Neinstein A., Jeng L., Halvorson M., Devoe D.J., et al. Nocturnal hypoglycemia detected with the Continuous Glucose Monitoring System in pediatric patients with type 1 diabetes. J. Pediatr. 141 (2002) 625-630
9. Wilkinson C.P., Ferris F.L., Klein R.E., Lee P.P., Agardh C.D., Davis M., et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology 110 (2003) 1677-1682
10. Levey A.S., Bosch J.P., Lewis J.B., Greene T., Rogers N., and Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann. Intern. Med. 130 (1999) 461-470
11. Hamm C.W., and Braunwald E. A classification of unstable angina revisited. Circulation 102 (2000) 118-122
12. Stahl M., and Berger W. Higher incidence of severe hypoglycemia leading to hospital admission in Type 2 diabetic patients treated with long-acting versus short-acting sulphonylureas. Diabet Med. 16 (1999) 586-590
13. Seltzer H.S. Drug-induced hypoglycemia. A review of 1418 cases. Endocrinol Metab Clin North Am 18 (1989) 163-183
14. Kowalska I., Straczkowski M., Nikolajuk A., Adamska A., Karczewska-Kupczewska M., Otziomek E., et al. Insulin resistance, serum adiponectin, and proinflammatory markers in young subjects with the metabolic syndrome. Metabolism 57 (2008) 1539-1544
15. Inchiostro S. Measurement of insulin sensitivity in Type 2 diabetes mellitus: comparison between KITT and HOMA-%S indices and evaluation of their relationship with the components of the insulin resistance syndrome. Diabet. Med. 22 (2005) 39-44
16. Frier B.M. Hypoglycaemic valleys: an under-recognised problem in type 2 diabetes?. Int. J. Clin. Pract. Suppl. (2002) 12-19
17. Voci C., Demattè L., Rossi E., Berti A., and De Rosa M. Diabetes pharmacoepidemiology approach to complications and overall costs through case-control methodology. Pharmacoepidemiol. Drug Saf. 15 Suppl. 1 (2006) 205
18. Stepka M., Rogala H., and Czyzyk A. Hypoglycemia: a major problem in the management of diabetes in the elderly. Aging (Milano) 5 (1993) 117-121
19. Holstein A., Plaschke A., and Egberts E.H. Clinical characterisation of severe hypoglycaemia-a prospective population-based study. Exp. Clin. Endocrinol. Diabetes 111 (2003) 364-369
20. Williamson J.D., Miller M.E., Bryan R.N., Lazar R.M., Coker L.H., Johnson J., et al. The Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes Study (ACCORD-MIND): rationale, design, and methods. Am. J. Cardiol. 99 (2007) 112i-122i
21. American Diabetes Association, Accord Trial Question & Answer, ADA website, 2008, http://www.diabetes.org/for-media/pr-accord-trail-QA-020608.jsp.
22. Bonds D.E., Kurashige E.M., Bergenstal R., Brillon D., Domanski M., Felicetta J.V., et al. Severe hypoglycemia monitoring and risk management procedures in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Am. J. Cardiol. 99 (2007) 80i-89i
23. Dluhy R.G., and McMahon G.T. Intensive glycemic control in the ACCORD and ADVANCE trials. N. Engl. J. Med. 358 (2008) 2630-2633
24. Huang E.S., Zhang Q., Gandra N., Chin M.H., and Meltzer D.O. The effect of comorbid illness and functional status on the expected benefits of intensive glucose control in older patients with type 2 diabetes: a decision analysis. Ann. Intern. Med. 149 (2008) 11-19
25. Cox D.J., Gonder-Frederick L., Ritterband L., Clarke W., and Kovatchev B.P. Prediction of severe hypoglycemia. Diabetes Care 30 (2007) 1370-1373