Labeling of stem cells with monocrystalline iron oxide for tracking and localization by magnetic resonance imaging

Microvascular Research

Volumn 78, Issue 1, 2009, Pages 132-139

  Li Calzi, Sergio ^a   Kent, David L ^b,c   Chang, Kyung Hee ^a   Padgett, Kyle R ^a   Afzal, Aqeela ^a   Chandra, Saurav B ^a   Caballero, Sergio ^a   English, Denis ^d   Garlington, Wendy ^a   Hiscott, Paul S ^b,c   Sheridan, Carl M ^b,c   Grant, Maria B ^a   Forder, John R ^a,e,f  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c Aut Even Hospital   (Ireland)

^d UNIVERSITY OF SOUTH FLORIDA   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^f University of Florida   (United States)

Author keywords

Cell localization; Cell therapy; Choroidal neovascularization; In vivo tracking; Magnetic resonance imaging; MION; Stem cells

Indexed keywords

MONOCRYSTALLINE IRON OXIDE NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRUCH MEMBRANE; CELL LABELING; CELL MIGRATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR IMAGING; MOUSE; NON INVASIVE PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; SUBRETINAL NEOVASCULARIZATION;

APOPTOSIS; CELL ADHESION; CELL DIFFERENTIATION; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; COLORING AGENTS; CONTRAST MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; FERROCYANIDES; FERROSOFERRIC OXIDE; FIBRONECTINS; HUMANS; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; STAINING AND LABELING; STEM CELLS;

MUS;

EID: 67349102257     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2009.03.007     Document Type: Article

References (37)

1. Allen M.J., and Meade T.J. Synthesis and visualization of a membrane-permeable MRI contrast agent. J. Biol. Inorg. Chem. 8 (2003) 746-750
2. Badea C.T., Drangova M., Holdsworth D.W., and Johnson G.A. In vivo small-animal imaging using micro-CT and digital subtraction angiography. Phys. Med. Biol. 53 (2008) R319-350
3. Barbash I.M., Chouraqui P., Baron J., Feinberg M.S., Etzion S., Tessone A., Miller L., Guetta E., Zipori D., Kedes L.H., Kloner R.A., and Leor J. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation 108 (2003) 863-868
4. Beck B., Plant D.H., Grant S.C., Thelwall P.E., Silver X., Mareci T.H., Benveniste H., Smith M., Collins C., Crozier S., and Blackband S.J. Progress in high field MRI at the University of Florida. Magma 13 (2002) 152-157
5. Bjornerud A., and Johansson L. The utility of superparamagnetic contrast agents in MRI: theoretical consideration and applications in the cardiovascular system. NMR Biomed. 17 (2004) 465-477
6. Bulte J.W., and Kraitchman D.L. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed. 17 (2004) 484-499
7. Bulte J.W., Duncan I.D., and Frank J.A. In vivo magnetic resonance tracking of magnetically labeled cells after transplantation. J. Cereb. Blood Flow Metab. 22 (2002) 899-907
8. Chan-Ling T., Baxter L., Afzal A., Sengupta N., Caballero S., Rosinova E., and Grant M.B. Hematopoietic stem cells provide repair functions after laser-induced Bruch's membrane rupture model of choroidal neovascularization. Am. J. Pathol. 168 (2006) 1031-1044
9. Crich S.G., Biancone L., Cantaluppi V., Duo D., Esposito G., Russo S., Camussi G., and Aime S. Improved route for the visualization of stem cells labeled with a Gd-/Eu-chelate as dual (MRI and fluorescence) agent. Magn. Reson. Med. 51 (2004) 938-944
10. Daldrup-Link H.E., Rudelius M., Piontek G., Metz S., Brauer R., Debus G., Corot C., Schlegel J., Link T.M., Peschel C., Rummeny E.J., and Oostendorp R.A. Migration of iron oxide-labeled human hematopoietic progenitor cells in a mouse model: in vivo monitoring with 1.5-T MR imaging equipment. Radiology 234 (2005) 197-205
11. Deans R.J., and Moseley A.B. Mesenchymal stem cells: biology and potential clinical uses. Exp. Hematol. 28 (2000) 875-884
12. Dodd C.H., Hsu H.C., Chu W.J., Yang P., Zhang H.G., Mountz Jr. J.D., Zinn K., Forder J., Josephson L., Weissleder R., Mountz J.M., and Mountz J.D. Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles. J. Immunol. Methods 256 (2001) 89-105
13. Espinosa-Heidmann D.G., Caicedo A., Hernandez E.P., Csaky K.G., and Cousins S.W. Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 44 (2003) 4914-4919
14. Espinosa-Heidmann D.G., Reinoso M.A., Pina Y., Csaky K.G., Caicedo A., and Cousins S.W. Quantitative enumeration of vascular smooth muscle cells and endothelial cells derived from bone marrow precursors in experimental choroidal neovascularization. Exp. Eye Res. 80 (2005) 369-378
15. Frank J.A., Miller B.R., Arbab A.S., Zywicke H.A., Jordan E.K., Lewis B.K., Bryant Jr. L.H., and Bulte J.W. Clinically applicable labeling of mammalian and stem cells by combining superparamagnetic iron oxides and transfection agents. Radiology 228 (2003) 480-487
16. Grant M.B., May W.S., Caballero S., Brown G.A., Guthrie S.M., Mames R.N., Byrne B.J., Vaught T., Spoerri P.E., Peck A.B., and Scott E.W. Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nat. Med. 8 (2002) 607-612
17. Harris J.R., Brown G.A., Jorgensen M., Kaushal S., Ellis E.A., Grant M.B., and Scott E.W. Bone marrow-derived cells home to and regenerate retinal pigment epithelium after injury. Invest. Ophthalmol. Vis. Sci. 47 (2006) 2108-2113
18. Herschman H.R. Micro-PET imaging and small animal models of disease. Curr. Opin. Immunol. 15 (2003) 378-384
19. Heyn C., Ronald J.A., Mackenzie L.T., MacDonald I.C., Chambers A.F., Rutt B.K., and Foster P.J. In vivo magnetic resonance imaging of single cells in mouse brain with optical validation. Magn. Reson. Med. 55 (2006) 23-29
20. Kang Y.S., Risbud S., Rabolt J.F., and Stroeve P. Synthesis and characterization of nanometer-size Fe3O4 and γ-Fe2O3 particles. Chem. Mater. 8 (1996) 2209-2211
21. Kiessling F. Noninvasive cell tracking. Handb. Exp. Pharmacol. (2008) 305-321
22. Lewin M., Carlesso N., Tung C.H., Tang X.W., Cory D., Scadden D.T., and Weissleder R. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat. Biotechnol. 18 (2000) 410-414
23. McKay R. Stem cells-hype and hope. Nature 406 (2000) 361-364
24. Oca-Cossio J., Mao H., Khokhlova N., Kennedy C.M., Kennedy J.W., Stabler C.L., Hao E., Sambanis A., Simpson N.E., and Constantinidis I. Magnetically labeled insulin-secreting cells. Biochem. Biophys. Res. Commun. 319 (2004) 569-575
25. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., Moorman M.A., Simonetti D.W., Craig S., and Marshak D.R. Multilineage potential of adult human mesenchymal stem cells. Science 284 (1999) 143-147
26. Rogers W.J., Meyer C.H., and Kramer C.M. Technology insight: in vivo cell tracking by use of MRI. Nat. Clin. Pract. Cardiovasc. Med. 3 (2006) 554-562
27. Ryan S.J. The development of an experimental model of subretinal neovascularization in disciform macular degeneration. Trans. Am. Ophthalmol. Soc. 77 (1979) 707-745
28. Segal M.S., Shah R., Afzal A., Perrault C.M., Chang K., Schuler A., Beem E., Shaw L.C., Li Calzi S., Harrison J.K., Tran-Son-Tay R., and Grant M.B. Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes. Diabetes 55 (2006) 102-109
29. Sengupta N., Caballero S., Mames R.N., Butler J.M., Scott E.W., and Grant M.B. The role of adult bone marrow-derived stem cells in choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 44 (2003) 4908-4913
30. Shapiro E.M., Sharer K., Skrtic S., and Koretsky A.P. In vivo detection of single cells by MRI. Magn. Reson. Med. 55 (2006) 242-249
31. Stroh A., Faber C., Neuberger T., Lorenz P., Sieland K., Jakob P.M., Webb A., Pilgrimm H., Schober R., Pohl E.E., and Zimmer C. In vivo detection limits of magnetically labeled embryonic stem cells in the rat brain using high-field (17.6 T) magnetic resonance imaging. Neuroimage 24 (2005) 635-645
32. Sundstrom J.B., Mao H., Santoianni R., Villinger F., Little D.M., Huynh T.T., Mayne A.E., Hao E., and Ansari A.A. Magnetic resonance imaging of activated proliferating rhesus macaque T cells labeled with superparamagnetic monocrystalline iron oxide nanoparticles. J. Acquir. Immune. Defic. Syndr. 35 (2004) 9-21
33. Thompson M., Wall D.M., Hicks R.J., and Prince H.M. In vivo tracking for cell therapies. Q. J. Nucl. Med. Mol. Imaging 49 (2005) 339-348
34. Weissleder R. Molecular imaging: exploring the next frontier. Radiology 212 (1999) 609-614
35. Weissleder R., and Mahmood U. Molecular imaging. Radiology 219 (2001) 316-333
36. Winnard Jr. P., and Raman V. Real time non-invasive imaging of receptor-ligand interactions in vivo. J. Cell. Biochem. 90 (2003) 454-463
37. Wu E.X., Tang H., and Jensen J.H. Applications of ultrasmall superparamagnetic iron oxide contrast agents in the MR study of animal models. NMR Biomed. 17 (2004) 478-483