Suppression of nitric oxide production in activated murine peritoneal macrophages in vitro and ex vivo by Scrophularia striata ethanolic extract

Journal of Ethnopharmacology

Volumn 124, Issue 1, 2009, Pages 166-169

  Azadmehr, Abbas ^a,b   Afshari, Afshin ^b   Baradaran, Behzad ^c   Hajiaghaee, Reza ^a   Rezazadeh, Shamsali ^a   Monsef Esfahani, Hamidreza ^d  

^a Institute of Medicinal Plants Iran   (Iran)

^b QAZVIN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Inflammation; Nitric oxide; Peritoneal macrophages; Scrophularia striata

Indexed keywords

ALCOHOL; GAMMA INTERFERON; HERBACEOUS AGENT; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRITE; SCROPHULARIA STRIATA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; EX VIVO STUDY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; SCROPHULARIA STRIATA; SCROPHULARIACEAE; SOLVENT EXTRACTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLAMMATION; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; NITRIC OXIDE; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; SCROPHULARIA;

MURINAE; MUS; SCROPHULARIA; SCROPHULARIACEAE;

EID: 67349099179     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.03.042     Document Type: Article

References (16)

1. Bas E., Recio M.C., Abdallah M., Manez S., Giner R.M., Cerda-Nicolas M., and Rios J.L. Inhibition of the pro-inflammatory mediators production and anti-inflammatory effect of the iridoid scrovalentinoside. Journal of Ethnopharmacology 110 (2007) 419-427
2. Bas E., Recio M.C., Manez S., Giner R.M., Escandell J.M., Lopez-Gines C., and Rios J.L. New insight into the inhibition of the inflammatory response to experimental delayed-type hypersensitivity reactions in mice by scropolioside A. European Journal of Pharmacology 555 (2007) 199-210
3. Bredt D.S., and Snyder S.H. Nitric oxide: a physiologic messenger molecule. Annual Review of Biochemistry 63 (1994) 175-195
4. Diaz A.M., Abad M.J., Fernandez L., Silvan A.M., De Santos J., and Bermejo P. Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity. Life Sciences 74 (2004) 2515-2526
5. 15N] Nitrit in biological fluids. Analytical Biochemistry 126 (1982) 131-138
6. Guzik T.J., Korbut R., and Adamek-Guzik T. Nitric oxide and superoxide in inflammation and immune regulation. Journal of Physiology and Pharmacology 54 (2003) 469-487
7. Hajiaghaee R., Monsef-Esfahani H.R., Khorramizadeh M.R., Saadat F., Shahverdi A.R., and Attar F. Inhibitory effect of aerial parts of Scrophularia striata on matrix metalloproteinases expression. Phytotherapy Research 21 (2007) 1127-1129
8. Ignarro L.J. Nitric oxide in the regulation of vascular function: an historical overview. Journal of Cardiac Surgery 17 (2002) 301-306
9. Kolb H., and Kolb-Bachofen V. Nitric oxide: a pathogenic factor in autoimmunity. Immunology Today 13 (1992) 157-160
10. MacMicking J.D., Nathan C., Hom G., Chartrain N., Fletcher D.S., Trumbauer M., Stevens K., Xie Q.W., Sokol K., and Hutchinson N. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81 (1995) 641-650
11. MacMicking J., Xie Q.W., and Nathan C. Nitric oxide and macrophage function. Annual Review of Immunology 15 (1997) 323-350
12. Moncada S., Palmer R.M.J., and Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacological Reviews 43 (1991) 109-142
13. Moretao M.P., Buchi D.F., Gorin P.A.J., Iacomini M., and Oliveira M.B.M. Effect of an acidic heteropolysaccharide (ARAGAL) from the gum of Anadenanthera colubrina (Angico branco) on peritoneal macrophage functions. Immunology Letters 89 (2003) 175-185
14. Nathan C. Nitric oxide as a secretory product of mammalian cells. The Journal of the Federation of American Societies for Experimental Biology 6 (1992) 3051-3064
15. Prast H., and Philippu A. Nitric oxide as a modulator of neuronal function. Progress in Neurobiology 64 (2001) 51-58
16. Schinella G.R., Tournier H.A., Prieto J.M., Mordujovich de Buschiazzo P., and Rios J.L. Antioxidant activity of anti-inflammatory plant extracts. Life Sciences 18 (2002) 1023-1033