Cell cycle: Akt Skps through

Nature Reviews Cancer

Volumn 9, Issue 5, 2009, Pages

  Chenette, Emily J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE B BETA; PROTEIN P27; S PHASE KINASE ASSOCIATED PROTEIN 2;

ARTICLE; CARCINOGENESIS; CELL CYCLE PROGRESSION; CELL MOTILITY; CELLULAR DISTRIBUTION; HUMAN; METASTASIS; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 67349098436     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc2649     Document Type: Article

References (2)

1. Lin, H.-K. et al. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB Nature Cell Biol. 8 Mar 2009 (doi:10.1038/ncb1849) | Gao, D. et al.Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APC-Cdh1- mediated Skp2 destruction Nature Cell Biol.8 Mar 2009 (doi 10.1038/ncb1847)
2. Frecas, D. & Pagano, M. Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer. Nature Rev. Cancer 8, 438-449 (2008).