Attenuation of skeletal muscle atrophy in cancer cachexia by d-myo-inositol 1,2,6-triphosphate

Cancer Chemotherapy and Pharmacology

Volumn 64, Issue 3, 2009, Pages 517-527

  Russell, S T ^a   Siren, P M A ^b   Siren, M J ^b,c   Tisdale, M J ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b IAM   (Sweden)

^c JGK Memorial Research Library and Laboratory   (Finland)

Author keywords

Alpha trinositol; Eukaryotic elongation factors; Eukaryotic initiation factors; Muscle atrophy; Protein kinase R (PKR)

Indexed keywords

ANGIOTENSIN II; CASPASE 3; CASPASE 8; HEXANOYLINOSITOL 1,2,6 TRISPHOSPHATE; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; INITIATION FACTOR 4E BINDING PROTEIN 1; INOSITOL 1,2,6 TRISPHOSPHATE; PROTEASOME; PROTEIN KINASE R; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; BODY MASS; CACHEXIA; CANCER MODEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; MALE; MALIGNANT NEOPLASTIC DISEASE; MOUSE; MUSCLE ATROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; WEIGHT REDUCTION;

ANIMALS; BODY WEIGHT; CACHEXIA; CARRIER PROTEINS; CASPASE 3; CASPASE 8; EUKARYOTIC INITIATION FACTOR-2; INOSITOL PHOSPHATES; MALE; MICE; MICE, INBRED STRAINS; MUSCLE FIBERS, SKELETAL; MUSCLE PROTEINS; MUSCULAR ATROPHY; NEOPLASMS, EXPERIMENTAL; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASES; RNA, DOUBLE-STRANDED; UBIQUITIN;

EID: 67349091104     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0899-z     Document Type: Article

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