메뉴 건너뛰기




Volumn 27, Issue 4, 2009, Pages 438-446

Selective thromboxane inhibition after vascular protectant AGI-1067: Results of assessment of lipoprotein profiles (ALPS) biomarkers in vitro and in vivo substudy

Author keywords

AGI 1067; Clinical trial; Platelets; Thromboxane; Vascular protectant

Indexed keywords

BETA THROMBOGLOBULIN; CALCIUM IONOPHORE; COLLAGEN; PADGEM PROTEIN; PLACEBO; PROBUCOL SUCCINATE; PROSTACYCLIN; THROMBOCYTE FACTOR 4; THROMBOXANE;

EID: 67349088389     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-008-0233-y     Document Type: Article
Times cited : (5)

References (43)
  • 1
    • 0037421497 scopus 로고    scopus 로고
    • Vascular biology of atherosclerosis: Overview and state of the art
    • Libby P (2003) Vascular biology of atherosclerosis: Overview and state of the art. Am J Cardiol 91(suppl):3A-6A
    • (2003) Am J Cardiol , vol.91 , Issue.SUPPL.
    • Libby, P.1
  • 2
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320:915-924
    • (1989) N Engl J Med , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 3
    • 0027365599 scopus 로고
    • Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant sensitive mechanism in human vascular endothelial cells
    • Marui N, Offermann MK, Swerlick R et al (1993) Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant sensitive mechanism in human vascular endothelial cells. J Clin Invest 92:1866-1874
    • (1993) J Clin Invest , vol.92 , pp. 1866-1874
    • Marui, N.1    Offermann, M.K.2    Swerlick, R.3
  • 4
    • 0027301258 scopus 로고
    • Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1 and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobuolin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase
    • Satriano JA, Shuldiner M, Hora K, Xing Y, Shan Z, Schlondorff D (1993) Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1 and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobuolin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase. J Clin Invest 92:1564-1571
    • (1993) J Clin Invest , vol.92 , pp. 1564-1571
    • Satriano, J.A.1    Shuldiner, M.2    Hora, K.3    Xing, Y.4    Shan, Z.5    Schlondorff, D.6
  • 5
    • 0032785562 scopus 로고    scopus 로고
    • Endothelial permeability and IL-6 production during hypoxia: Role of ROS in signal transduction
    • Ali MH, Schlidt SA, Chandel NS, Hynes KL, Schumacker PT, Gewertz BL (1999) Endothelial permeability and IL-6 production during hypoxia: Role of ROS in signal transduction. Am J Physiol 277(5 Pt 1):L1057-L1065
    • (1999) Am J Physiol , vol.277 , Issue.5 PART 1
    • Ali, M.H.1    Schlidt, S.A.2    Chandel, N.S.3    Hynes, K.L.4    Schumacker, P.T.5    Gewertz, B.L.6
  • 9
    • 0037421506 scopus 로고    scopus 로고
    • Chemistry and pharmacology of vascular protectants: A novel approach to the treatment of atherosclerosis and coronary artery disease
    • Wasserman MA, Sundell CL, Kunsch C, Edwards D, Meng CQ, Medford RM (2003) Chemistry and pharmacology of vascular protectants: A novel approach to the treatment of atherosclerosis and coronary artery disease. Am J Cardiol 91(3A):34A-40A
    • (2003) Am J Cardiol , vol.91 , Issue.3 A
    • Wasserman, M.A.1    Sundell, C.L.2    Kunsch, C.3    Edwards, D.4    Meng, C.Q.5    Medford, R.M.6
  • 11
    • 0344738598 scopus 로고    scopus 로고
    • ICAM-1 and VCAM-1 expression by endothelial cells grown on fibronectin-coated TCPS and PS
    • van der Zijpp YJ, Poot AA, Feijen J (2003) ICAM-1 and VCAM-1 expression by endothelial cells grown on fibronectin-coated TCPS and PS. J Biomed Mater Res A 65:51-59
    • (2003) J Biomed Mater Res A , vol.65 , pp. 51-59
    • van der Zijpp, Y.J.1    Poot, A.A.2    Feijen, J.3
  • 12
    • 0036332652 scopus 로고    scopus 로고
    • Transient platelet interaction induces MCP-1 production by endothelial cells via I kappa B kinase complex activation
    • Gawaz M, Page S, Massberg S et al (2002) Transient platelet interaction induces MCP-1 production by endothelial cells via I kappa B kinase complex activation. Thromb Haemost 88:307-314
    • (2002) Thromb Haemost , vol.88 , pp. 307-314
    • Gawaz, M.1    Page, S.2    Massberg, S.3
  • 13
    • 0036070553 scopus 로고    scopus 로고
    • Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: Role of endothelial PAF generation
    • Mayer K, Merfels M, Muhly-Reinholz M et al (2002) Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: Role of endothelial PAF generation. Am J Physiol Heart Circ Physiol 283:H811-H818
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Mayer, K.1    Merfels, M.2    Muhly-Reinholz, M.3
  • 14
    • 33749574567 scopus 로고    scopus 로고
    • The in vitro effects of a novel vascular protectant, AGI-1067, on platelet aggregation and major receptor expression in subjects with multiple risk factors for vascular disease
    • Serebruany V, Malinin A, Scott R (2006) The in vitro effects of a novel vascular protectant, AGI-1067, on platelet aggregation and major receptor expression in subjects with multiple risk factors for vascular disease. J Cardiovasc Pharmacol Ther 11:191-196
    • (2006) J Cardiovasc Pharmacol Ther , vol.11 , pp. 191-196
    • Serebruany, V.1    Malinin, A.2    Scott, R.3
  • 15
    • 67349149076 scopus 로고    scopus 로고
    • National Cholesterol Education Program National Heart, Lung, and Blood Institute National Institutes of Health. NIH Publication No. 01-3670, May
    • National Cholesterol Education Program National Heart, Lung, and Blood Institute National Institutes of Health. NIH Publication No. 01-3670, May (2001)
    • (2001)
  • 16
    • 0348149055 scopus 로고    scopus 로고
    • Sample size re-estimation in group-sequential response-adaptive clinical trials
    • Morgan CC (2003) Sample size re-estimation in group-sequential response-adaptive clinical trials. Stat Med 22:3843-3857
    • (2003) Stat Med , vol.22 , pp. 3843-3857
    • Morgan, C.C.1
  • 17
    • 1842338658 scopus 로고    scopus 로고
    • Probucol and multivitamins in the prevention of restenosis after coronary angioplasty
    • Tardif JC, Côté G, Lespérance J et al (1997) Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. N Engl J Med 337:365-372
    • (1997) N Engl J Med , vol.337 , pp. 365-372
    • Tardif, J.C.1    Côté, G.2    Lespérance, J.3
  • 18
    • 0345628014 scopus 로고    scopus 로고
    • Prevention of restenosis after angioplasty in small coronary arteries with probucol
    • Rodés J, Tardif JC, Lespérance J et al (1998) Prevention of restenosis after angioplasty in small coronary arteries with probucol. Circulation 97:429-436
    • (1998) Circulation , vol.97 , pp. 429-436
    • Rodés, J.1    Tardif, J.C.2    Lespérance, J.3
  • 19
    • 0035129883 scopus 로고    scopus 로고
    • Impact of residual plaque burden after balloon angioplasty in the MultiVitamins and Probucol (MVP) trial
    • Tardif JC, Côté G, Lespérance J et al (2001) Impact of residual plaque burden after balloon angioplasty in the MultiVitamins and Probucol (MVP) trial. Can J Cardiol 17:49-55
    • (2001) Can J Cardiol , vol.17 , pp. 49-55
    • Tardif, J.C.1    Côté, G.2    Lespérance, J.3
  • 20
    • 0030768434 scopus 로고    scopus 로고
    • Effectiveness of an antioxidant in preventing restenosis after percutaneous transluminal coronary angioplasty: The Probucol Angioplasty Restenosis Trial
    • Yokoi H, Daida H, Kuwabara Y et al (1997) Effectiveness of an antioxidant in preventing restenosis after percutaneous transluminal coronary angioplasty: The Probucol Angioplasty Restenosis Trial. J Am Coll Cardiol 30:855-862
    • (1997) J Am Coll Cardiol , vol.30 , pp. 855-862
    • Yokoi, H.1    Daida, H.2    Kuwabara, Y.3
  • 21
    • 0030006105 scopus 로고    scopus 로고
    • Preventive effects of probucol on restenosis after percutaneous transluminal coronary angioplasty
    • Watanabe K, Sekyia M, Ikeda S et al (1996) Preventive effects of probucol on restenosis after percutaneous transluminal coronary angioplasty. Am Heart J 132:23-29
    • (1996) Am Heart J , vol.132 , pp. 23-29
    • Watanabe, K.1    Sekyia, M.2    Ikeda, S.3
  • 22
    • 0030036185 scopus 로고    scopus 로고
    • Effectiveness of probucol in preventing restenosis after percutaneous transluminal coronary angioplasty
    • Lee YJ, Daida H, Yokoi H et al (1996) Effectiveness of probucol in preventing restenosis after percutaneous transluminal coronary angioplasty. Jpn Heart J 37:327-332
    • (1996) Jpn Heart J , vol.37 , pp. 327-332
    • Lee, Y.J.1    Daida, H.2    Yokoi, H.3
  • 23
    • 0037417930 scopus 로고    scopus 로고
    • Effects of AGI-1067 and probucol after percutaneous coronary interventions
    • Tardif JC, Gregoire J, Schwartz L et al (2003) Effects of AGI-1067 and probucol after percutaneous coronary interventions. Circulation 107:552-558
    • (2003) Circulation , vol.107 , pp. 552-558
    • Tardif, J.C.1    Gregoire, J.2    Schwartz, L.3
  • 24
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM, Maseri A (2002) Inflammation and atherosclerosis. Circulation 105:1135-1143
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 25
    • 1342302187 scopus 로고    scopus 로고
    • Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: A novel antioxidant and anti-inflammatory agent
    • Kunsch C, Luchoomun J, Grey JY et al (2004) Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: A novel antioxidant and anti-inflammatory agent. J Pharmacol Exp Ther 308:820-829
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 820-829
    • Kunsch, C.1    Luchoomun, J.2    Grey, J.Y.3
  • 26
    • 0027476229 scopus 로고
    • An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium
    • Li H, Cybulsky MI, Gimbrone MA Jr, Libby P (1993) An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb 13:197-204
    • (1993) Arterioscler Thromb , vol.13 , pp. 197-204
    • Li, H.1    Cybulsky, M.I.2    Gimbrone Jr., M.A.3    Libby, P.4
  • 27
    • 0033597952 scopus 로고    scopus 로고
    • Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation
    • Iiyama K, Hajra L, Iiyama M, Li H, DiChiara M, Medoff BD, Cybulsky MI (1999) Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ Res 85:199-207
    • (1999) Circ Res , vol.85 , pp. 199-207
    • Iiyama, K.1    Hajra, L.2    Iiyama, M.3    Li, H.4    DiChiara, M.5    Medoff, B.D.6    Cybulsky, M.I.7
  • 28
    • 0027301258 scopus 로고
    • Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1 and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobuolin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase
    • Satriano JA, Shuldiner M, Hora K, Xing Y, Shan Z, Schlondorff D (1993) Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1 and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobuolin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase. J Clin Invest 92:1564-1571
    • (1993) J Clin Invest , vol.92 , pp. 1564-1571
    • Satriano, J.A.1    Shuldiner, M.2    Hora, K.3    Xing, Y.4    Shan, Z.5    Schlondorff, D.6
  • 29
    • 0027180021 scopus 로고
    • Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques: Implications for the mode of progression of advanced coronary atherosclerosis
    • O'Brien KD, Allen MD, McDonald TO, Chait A, Harlan JM, Fishbein D, McCarty J, Ferguson M, Hudkins K, Benjamin CD (1993) Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques: Implications for the mode of progression of advanced coronary atherosclerosis. J Clin Invest 92:945-951
    • (1993) J Clin Invest , vol.92 , pp. 945-951
    • O'Brien, K.D.1    Allen, M.D.2    McDonald, T.O.3    Chait, A.4    Harlan, J.M.5    Fishbein, D.6    McCarty, J.7    Ferguson, M.8    Hudkins, K.9    Benjamin, C.D.10
  • 33
    • 0016748441 scopus 로고
    • Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides
    • Hamberg M, Svensson J, Samuelsson B (1975) Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci USA 72:2994
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 2994
    • Hamberg, M.1    Svensson, J.2    Samuelsson, B.3
  • 34
    • 0017183618 scopus 로고
    • Thromboxanes: Selective biosynthesis and distinct biological properties
    • Needleman P, Minkes M, Raz A (1976) Thromboxanes: Selective biosynthesis and distinct biological properties. Science 193:163-165
    • (1976) Science , vol.193 , pp. 163-165
    • Needleman, P.1    Minkes, M.2    Raz, A.3
  • 35
    • 0020617819 scopus 로고
    • The source of thromboxane and prostaglandins in experimental inflammation
    • Higgs GA, Monsada S, Salmon JA, Seager K (1983) The source of thromboxane and prostaglandins in experimental inflammation. Br J Pharmacol 79:863-868
    • (1983) Br J Pharmacol , vol.79 , pp. 863-868
    • Higgs, G.A.1    Monsada, S.2    Salmon, J.A.3    Seager, K.4
  • 36
    • 0031018309 scopus 로고    scopus 로고
    • von Willerbrand factor
    • Ruggeri ZM (1997) von Willerbrand factor. J Clin Invest 99:559-564
    • (1997) J Clin Invest , vol.99 , pp. 559-564
    • Ruggeri, Z.M.1
  • 37
    • 0023140204 scopus 로고
    • Overview of physiological and pathophysiological effects of thromboxane A 2
    • Ogletree ML (1987) Overview of physiological and pathophysiological effects of thromboxane A 2. Fed Proc 46:133-138
    • (1987) Fed Proc , vol.46 , pp. 133-138
    • Ogletree, M.L.1
  • 38
    • 0023142783 scopus 로고
    • A pharmacological approach to thromboxane receptor antagonism
    • Lefer AM, H Darius (1987) A pharmacological approach to thromboxane receptor antagonism. Fed Proc 46:144-814
    • (1987) Fed Proc , vol.46 , pp. 144-814
    • Lefer, A.M.1    Darius, H.2
  • 39
    • 0018937781 scopus 로고
    • The functioning of blood platelets
    • Zucker MB (1980) The functioning of blood platelets. Sci Am 242:86-103
    • (1980) Sci Am , vol.242 , pp. 86-103
    • Zucker, M.B.1
  • 40
    • 0027936171 scopus 로고
    • Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor
    • Raychowdhury MK, Yukawa M, Collins LJ, McGrail SH, Kent KC, Ware JA (1994) Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor. J Biol Chem 269:19256-19261
    • (1994) J Biol Chem , vol.269 , pp. 19256-19261
    • Raychowdhury, M.K.1    Yukawa, M.2    Collins, L.J.3    McGrail, S.H.4    Kent, K.C.5    Ware, J.A.6
  • 41
    • 0031595603 scopus 로고    scopus 로고
    • Stimulation with thromboxane A2 (TXA2) receptor agonist enhances ICAM-1, VCAM-1 or ELAM-1 expression by human vascular endothelial cells
    • Ishizuka T, Kawakami M, Hidaka T, Matsuki Y, Takamizawa M, Suzuki K, Kurita A, Nakamura H (1998) Stimulation with thromboxane A2 (TXA2) receptor agonist enhances ICAM-1, VCAM-1 or ELAM-1 expression by human vascular endothelial cells. Clin Exp Immunol 112:464-470
    • (1998) Clin Exp Immunol , vol.112 , pp. 464-470
    • Ishizuka, T.1    Kawakami, M.2    Hidaka, T.3    Matsuki, Y.4    Takamizawa, M.5    Suzuki, K.6    Kurita, A.7    Nakamura, H.8
  • 42
    • 0034746834 scopus 로고    scopus 로고
    • Necessity of thromboxane A2 for initiation of platelet-mediated contact sensitivity: Dual activation of platelets and vascular endothelial cells
    • Mitsuhashi M, Tanaka A, Fujisawa C, Kawamoto K, Itakura A, Takaku M, Hironaka T, Sawada S, Matsuda H (2001) Necessity of thromboxane A2 for initiation of platelet-mediated contact sensitivity: Dual activation of platelets and vascular endothelial cells. J Immunol 166:617-623
    • (2001) J Immunol , vol.166 , pp. 617-623
    • Mitsuhashi, M.1    Tanaka, A.2    Fujisawa, C.3    Kawamoto, K.4    Itakura, A.5    Takaku, M.6    Hironaka, T.7    Sawada, S.8    Matsuda, H.9
  • 43
    • 0033975104 scopus 로고    scopus 로고
    • The role of soluble and platelet-bound P-selectin in discriminating cardiac from non-cardiac chest pain at presentation in the emergency department
    • Gurbel PA, Kereiakes DJ, Dalesandro MR, Bahr RD, O'Connor CM, Serebruany VL (2000) The role of soluble and platelet-bound P-selectin in discriminating cardiac from non-cardiac chest pain at presentation in the emergency department. Am Heart J 139:320-328
    • (2000) Am Heart J , vol.139 , pp. 320-328
    • Gurbel, P.A.1    Kereiakes, D.J.2    Dalesandro, M.R.3    Bahr, R.D.4    O'Connor, C.M.5    Serebruany, V.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.