VEGF secretion by macrophages is stimulated by lipid and protein components of OxLDL via PI3-kinase and PKCζ activation and is independent of OxLDL uptake

Atherosclerosis

Volumn 204, Issue 1, 2009, Pages 47-54

  Riazy, Maziar ^a   Chen, Johnny H ^a   Steinbrecher, Urs P ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Atherosclerosis; Macrophage; OxLDL; PI3K; PKC ; Scavenger Receptor

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; ARACHIDONIC ACID; CD36 ANTIGEN; COPPER; ENZYME INHIBITOR; FERROUS ION; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C EPSILON; PROTEIN KINASE INHIBITOR; SCAVENGER RECEPTOR A; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIPID OXIDATION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS, CD36; BIOLOGICAL TRANSPORT; CELL LINE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIPOPROTEINS, LDL; MACROPHAGES; MICE; MICE, KNOCKOUT; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; SCAVENGER RECEPTORS, CLASS A; SCAVENGER RECEPTORS, CLASS E; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 67349088024     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2008.08.004     Document Type: Article

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