Effects of long-term ovariectomy on anxiety and behavioral despair in rats

Physiology and Behavior

Volumn 97, Issue 3-4, 2009, Pages 420-425

  de Chaves, G ^a   Moretti, M ^a   Castro, A A ^a   Dagostin, W ^a   da Silva, G G ^a   Boeck, C R ^a   Quevedo, J ^a   Gavioli, E C ^a,b  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

17 estradiol; Aging; Animal behavior; Female rat; Ovariectomy

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; DEPRESSION; FEMALE; HOPELESSNESS; LOCOMOTION; MAZE TEST; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SWIMMING;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BEHAVIORAL SYMPTOMS; BODY WEIGHT; DISEASE MODELS, ANIMAL; ESTRADIOL; EXPLORATORY BEHAVIOR; FEMALE; MAZE LEARNING; OVARIECTOMY; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; SWIMMING; VAGINA;

EID: 67349085786     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2009.03.016     Document Type: Article

References (48)

1. Kessler R.C., McGonagle K.A., Swartz M., Blazer D., and Nelson C.B. Sex and depression in the National Comorbidity Survey. I: lifetime prevalence, chronicity and recurrence. J Affect Disord 29 2-3 (1993) 85-96
2. Paoletti A.M., Floris S., Mannias M., Orru M., Crippa D., Orlandi R., et al. Evidence that cyproterone acetate improves psychological symptoms and enhances the activity of the dopaminergic system in postmenopause. J Clin Endocrinol Metab 86 (2001) 608-612
3. Pisani G., Facioni L., Fiorani F., and Pisani G. Psychosexual problems in menopause. Min. Ginecol. 50 (1998) 77-81
4. Schmidt P.J. Mood, depression, and reproductive hormones in the menopausal transition. Am J Med 118 (2005) 54-58
5. Avis N.E., Stellato R., Crawford S., Bromberger J., Ganz P., Cain V., et al. Is there a menopausal syndrome? Menopausal status and symptoms across racial/ethnic groups. Soc Sci Med 2 (2001) 345-356
6. Alexander J.L., Dennerstein L., Kotz K., and Richardson G. Women, anxiety and mood: a review of nomenclature, comorbidity and epidemiology. Expert Rev Neurother 7 11 Suppl (2007) S45-S58
7. Weissman M.M., and Olfson M. Depression in women: implications for health care research. Science 269 (1995) 799-801
8. Alexander J.L. Quest for timely detection and treatment of women with depression. J Manag Care Pharm 13 9 Suppl A (2007) S3-11
9. Taylor M. Psychological consequences of surgical menopause. J Reprod Med 6 (2001) 317-324
10. Marcondes F.K., Miguel K.J., Melo L.L., and Spadari-Bratfisch R.C. Estrous cycle influences the response of female rats in the elevated plus-maze test. Physiol. Behav. 74 (2001) 435-440
11. Zuluaga M.J., Agrati D., Pereira M., Uriarte N., Fernández-Guasti A., and Ferreira A. Experimental anxiety in the black and white model in cycling, pregnant and lactating rats. Physiol Behav 84 2 (2005) 279-286
12. Frye C.A., Petralia S.M., and Rhodes M.E. Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3α,5α-THP. Pharmacol Biochem Behav 67 (2000) 587-596
13. Frye C.A., and Walf A.A. Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats. Horm Behav 41 (2002) 306-315
14. Estrada-Camarena E., Fernandez-Guasti A., and Lopez-Rubalcava C. Antidepressant-like effect of different estrogenic compounds in the forced swimming test. Neuropsychopharmacology 28 (2003) 830-838
15. Frye C.A., and Walf A.A. Estrogen and/or progesterone systemically or to the amygdala can have anxiety, fear, and pain reducing effects in ovariectomized rats. Behav Neurosci 118 (2004) 306-313
16. Frye C.A., and Wawrzycki J. Effect of prenatal stress and gonadal hormone condition on depressive behaviors of female and male rats. Horm Behav 44 (2003) 319-326
17. Rachman I.M., Unnerstall J.R., Pfaff D.W., and Cohen R.S. Estrogen alters behavior and forebrain c-fos expression in ovariectomized rats subjected to the forced swim test. Proc Natl Acad Sci USA 95 (1998) 13,941-13,946
18. Slater J., and Blizard D.A. A reevaluation of the relation between estrogen and emotionality in female rats. J Comp Physiol Psychol 90 (1976) 755-764
19. Walf A.A., and Frye C.A. Estradiol's effects to reduce anxiety and depressive behavior may be mediated by estradiol dose and restraint stress. Neuropsychopharmacology 30 (2005) 1288-1301
20. Walf A.A., and Frye C.A. ERβ-selective estrogen receptor modulators produce antianxiety behavior when administered systemically to ovariectomized rats. Neuropsychopharmacology 30 (2005) 1598-1609
21. Walf A.A., Rhodes M.E., and Frye C.A. Anti-depressant effects of ERβ selective estrogen receptor modulators in the forced swim test. Pharm Biochem Behav 78 (2004) 523-529
22. Gurkan L., Ekeland A., Gautvik K.M., Langeland N., Ronningen H., and Solheim L.F. Bone changes after castration in rats: a model for osteoporosis. Acta Orthop Scand 57 (1986) 67-70
23. Kalu D.N., Liu C.C., Hardin R.R., and Hollis B.W. The aged rat model of ovarian hormone deficiency bone loss. Endocrinology 124 (1989) 7-16
24. Kalu D.N. The ovariectomized rat model of postmenopausal bone loss. Bone Miner 15 (1991) 175-191
25. Andreatini R., and Bacellar L.F. The relationship between anxiety and depression in animal models: a study using the forced swimming test and elevated plus-maze. Braz. J. Med. Biol. Res. 32 9 (1999) 1121-1126
26. Robertson M.C., Owens R.E., Klindt J., and Friesen H.G. Ovariectomy leads to a rapid increase in rat placental lactogen secretion. Endocrinology (1984) 1805-1811
27. Marcondes F.K., Bianchi F.J., and Tanno A.P. Determination of the estrous cycle phases of rats: some helpful considerations. Braz J Biol 62 4A (2002) 609-614
28. Pellow S., Chopen P., File S.E., and Briley M. Validation of plus-maze as a measure of anxiety in the rat. J Neurosci Meth 14 (1985) 149-167
29. Rodgers R.J., and Dalvi A. Anxiety, defence and the elevated plus-maze. Neurosci Biobehav Rev 21 (1997) 801-810
30. Porsolt R.D., Le Pichon M., and Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 266 5604 (1977) 730-732
31. Fernandez-Guasti A., and Picazo O. Changes in burying behavior during the estrous cycle: effect of estrogen and progesterone. Psychoneuroendocrinology 17 (1992) 681-689
32. Picazo O., and Fernandez-Guasti A. Changes in experimental anxiety during pregnancy and lactation. Physiol Behav 54 (1993) 295-299
33. Laconi M.R., Casteller G., Gargiulo P.A., Bregonzio C., and Cabrera R.J. The anxiolytic effect of allopregnanolone is associated with gonadal hormonal status in female rats. Eur J Pharmacol 417 (2001) 111-116
34. Reddy D.S. Pharmacology of endogenous neuroactive steroids. Crit Rev Neurobiol 15 (2003) 197-234
35. Gomez C., Saldivar-Gonzalez A., Delgado G., and Rodriguez R. Rapid anxiolytic activity of progesterone and pregnanolone in male rats. Pharmacol Biochem Behav 72 (2002) 543-550
36. Picazo O., Estrada-Camarena E., and Hernandez-Aragon A. Influence of the post-ovariectomy time frame on the experimental anxiety and the behavioural actions of some anxiolytic agents. Eur J Pharmacol 530 (2006) 88-94
37. Bachmann G. Physiologic aspects of natural and surgical menopause. J Reprod Med 46 3 Suppl (2001) 307-315
38. Henderson V.W., and Sherwin B.B. Surgical versus natural menopause: cognitive issues. Menopause 14 3 Pt 2 (2007) 572-579
39. Daniel J.M., Hulst J.L., and Berbling J.L. Estradiol replacement enhances working memory in middle-aged rats when initiated immediately after ovariectomy but not after a long-term period of ovarian hormone deprivation. Endocrinology 147 1 (2006) 607-614
40. Okada M., Hayashi N., Kometani M., Nakao K., and Inukai T. Influences of ovariectomy and continuous replacement of 17beta-estradiol on the tail skin temperature and behavior in the forced swimming test in rats. Jpn J Pharmacol 73 1 (1997) 93-96
41. Bekku N., and Yoshimura H. Animal model of menopausal depressive-like state in female mice: prolongation of immobility time in the forced swimming test following ovariectomy. Psychopharmacology (Berl) 183 3 (2005) 300-307
42. Bekku N., Yoshimura H., and Araki H. Factors producing a menopausal depressive-like state in mice following ovariectomy. Psychopharmacology (Berl) 187 2 (2006) 170-180
43. Bimonte-Nelson H.A., Singleton R.S., Hunter C.L., Price K.L., Moore A.B., and Granholm A.C. Ovarian hormones and cognition in the aged female rat: I. Long-term, but not short-term, ovariectomy enhances spatial performance. Behav Neurosci 117 6 (2003) 1395-1406
44. Kasckow J.W., Segar T.M., Xiao C., Furay A.R., Evanson N.K., Ostrander M.M., et al. Stability of neuroendocrine and behavioral responsiveness in aging Fischer 344/Brown-Norway hybrid rats. Endocrinology 146 7 (2005) 3105-3112
45. Onodera T., Watanabe R., Tha K.K., Hayashi Y., Murayama T., Okuma Y., et al. Depressive behavior and alterations in receptors for dopamine and 5-hydroxytryptamine in the brain of the senescence accelerated mouse (SAM)-P10. Jpn J Pharmacol 83 4 (2000) 312-318
46. Zhao H., Tian Z., Hao J., and Chen B. Extragonadal aromatization increases with time after ovariectomy in rats. Reprod Biol Endocrinol. 21 (2005) 3-6
47. Shors T.J., Pickett J., Wood G., and Paczynski M. Acute stress persistently enhances estrogen levels in the female rat. Stress 3 2 (1999) 163-171
48. Ricciardi M.P., Pellegrini A., Grieco M., Marroni P., and Materazzi F. Effects of stress on adrenal steroidogenesis blockade by aminoglutethimide. In Vivo 6 1 (1992) 103-106