Combining two-dimensional diffusion-ordered nuclear magnetic resonance spectroscopy, imaging desorption electrospray ionization mass spectrometry, and direct analysis in real-time mass spectrometry for the integral investigation of counterfeit pharmaceuticals

Analytical Chemistry

Volumn 81, Issue 12, 2009, Pages 4803-4812

  Nyadong, Leonard ^a   Harris, Glenn A ^a   Balayssac, Stéphane ^b   Galhena, Asiri S ^a   Malet Martino, Myriam ^b   Martino, Robert ^b   Parry, R Mitchell ^a   Wang, May Dongmei ^a   Fernández, Facundo M ^a   Gilard, Véronique ^b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b Universite Toulouse III Paul Sabatier   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2D DOSY; ACTIVE PHARMACEUTICAL INGREDIENTS; ANTIMALARIAL DRUG; ARTESUNATE; COUNTERFEIT DRUGS; DESORPTION ELECTROSPRAY IONIZATION MASS SPECTROMETRIES; DEVELOPED COUNTRIES; DIRECT ANALYSIS; DRUG RESISTANCE; GRAPHICAL REPRESENTATIONS; HIGH DEMAND; IMAGING MODES; INSTRUMENTAL ANALYSIS; INTEGRAL INVESTIGATION; REAL-TIME MASS SPECTROMETRY; SOUTHEAST ASIA; SPATIALLY RESOLVED; SURFACE COMPOSITIONS;

DESORPTION; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; GRAPHIC METHODS; IONIZATION; MAGNETIC RESONANCE SPECTROMETERS; MASS SPECTROMETERS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PARTICLE DETECTORS; RESONANCE; SPECTRUM ANALYSIS; SUGAR (SUCROSE); TWO DIMENSIONAL;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ARTESUNATE; COUNTERFEIT DRUG; DEXTRIN; ILLICIT DRUG; LACTOSE; STARCH; STEARIC ACID; SUCROSE; UNCLASSIFIED DRUG;

ARTICLE; DESORPTION ELECTROSPRAY IONIZATION MASS SPECTROMETRY; DRUG FORMULATION; ELECTROSPRAY MASS SPECTROMETRY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REAL TIME MASS SPECTROMETRY; TWO DIMENSIONAL DIFFUSION ORDERED NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANTIMALARIALS; DRUG COMPOUNDING; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TABLETS;

EID: 67249163366     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac900384j     Document Type: Article

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