Advance on safety evaluation of carrageenan

Zhongguo Zhongyao Zazhi

Volumn 34, Issue 5, 2009, Pages 512-514

  Liang, Aihua ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Carrageenan; Safety; Tumor

Indexed keywords

CARRAGEENAN;

ARTICLE; COLITIS; INTESTINE INJURY; INTESTINE MUCOSA; NONHUMAN; RISK ASSESSMENT; TUMOR GROWTH;

ANIMALS; CARRAGEENAN; DRUG EVALUATION, PRECLINICAL; DRUG TOXICITY; PLANT EXTRACTS; SEAWEED;

EID: 67249144871     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Joanne K, tobacman. Review of harmful gastrointestinal effects of carrageenan in animal experiments[J]. Environ Health Perspect,2001,109(10):983.
2. Wakabayashi K, inagaki T, Fujimoto Y, et al. Induction by degraded carrageenan of colorectal tumors in rats[J]. Cancer Lett,1978,4:171.
3. Oohashi Y, Ishioka T T, Wakabayashi K, et al. A study of carcinogenesis induced by degraded carrageenan arising from squamous metaplasia of the rat colorectum[J]. Cancer Lett,1981,14:267.
4. Oohashi Y, Kitamura S, Wakabayashi K, et al. Irreversibility of degraded carrageenaninduced colorectal squamous metaplasia in rats[J]. Gann,1979,70:391.
5. Watanabe K, Reddy B S, Wong C Q, et al. Effect of dietary undegraded carrageenan on colon carcinogenesis in f344 rats treated with azoxymethane or methylnitrosourea[J]. Cancer Res,1978,38:4427.
6. Corpet D E, Tach S, Pr Claire M. Carrageenan given as a jelly, does not initiate, but promotes the growth of aberrant crypt foci in the rat colon[J]. Cancer Lett,1997,114:53.
7. Arakawa S, Okumua M, Yamada S, et al. Enhancing effect of carrageenan on the induction of rat colonic tumors by 1, 2-dimethylhydrazine and its relation to-glucuronidase activities in feces and other tissues[J]. J Nutr Sci Vitaminol (Tokyo),1986,32:481.
8. Kawaura A, Shibata M, togei K, et al. Effect of dietary degraded carrageenan on intestinal carcinogenesis in rats treated with 1, 2-dimethylhydrazine dihydrochloride[J]. Tokushima J Exp Med,1982,29-125. (Pubitemid 13226927)
9. Wilcox D K, Higgins J, Bertram T A. Colonic epithelial cell proliferation in a rat model of nongenotoxin-induced colonic neoplasia[J]. Lab invest,1992,67:405.
10. Calvert R J, Reicks M. Alterations in colonic thymidine kinase enzyme activity induced by consumption of various dietary fibers[J]. Proc Soc Exp Biol Med,1988,189:45.
11. Watt J, Mclean C, Marcus R. Degradation of carrageenan for the experimental production of ulcers in the colon[J]. J Pharm Pharmacol,1979,31: 645. (Pubitemid 9257313)
12. Marcus S N, Marcus A J, Marcus R, et al. The pre-ulcerative phase of carrageenan-induced colonic ulceration in the guinea-pig[J]. Int J Exp Pathol,1992,73:515.
13. Grasso P, Gangolli S D, Butterworth KR, et al. Studies on degraded carrageenan in rats and guineapigs[J]. Food Cosmet Toxicol,1975,13:195.
14. Abraham R, Fabian R J, Golberg M B, et al. Role of lysosomes in carrageenan-induced cecal ulceration[J]. Gastroenterology,1974,67:1169.
15. Van Der Waaif D, Cohen B J, et al. Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram-negative intestinal microflora[J]. Gastroenterology,1974,67:460.
16. Watt J, Mclean C, Marcus R. Degradation of carrageenan for the experimental production of ulcers in the colon[J]. J Pharm Pharmacol,1979,31: 645. (Pubitemid 9257313)
17. Watt J, Marcus R. Ulcerative colitis in the guinea-pig caused by seaweed extract[J]. J Pharm Pharmacol,1969,21:187.
18. Marcus S N, Marcus A J, Marcus R, et al. The pre-ulcerative phase of carrageenan-induced colonic ulceration in the guinea-pig[J]. Int J Exp Pathol,1992,73:515.
19. Borthakur A, Bhattacharyya S, Dudeja P K, et al. Carrageenan induces interleukin-8 production through distinct bcl 10 pathway in normal human colonic epithelial Cells[J]. Am J Physiol Gastrointest Liver Physiol,2007,292:829. (Pubitemid 46440382)
20. Bekemeier H, Hirschelmann R, Giessler A J. Carrageenin-induced thrombosis in rats and mice: a model for testing antithrombotic substances[J]. Agents Actions,1985,16(5):446.
21. Bekemeier H, Hirschelmann R, Giessler A J. Carrageenin-induced thrombosis in the rat and mouse as a test model of substances influencing thrombosis[J]. Biomed Biochim Acta,1984,43(8/9):347.
22. Bekemeier H, Hirschelmann R. Influence of serotonin, serotonin antagonists, some vasoactive substances and temperature on carrageenin-induced tail thrombosis in rats and mice[J]. Agents Actions,1986,18(5/6):581. (Pubitemid 16048516)
23. Levy L. Carrageenan paw oedema in the mouse[J]. Life Sci,1969,8:601.
24. Sugishita E, Amagaya S, Ogihara Y. Antiinflammatory testing methods: comparative evaluation of mice and rats[J]. J Pharmacobiodyn,1981,8:565. (Pubitemid 11011489)
25. Posadas I, Bucci M, Roviezzo F, et al. Carrageenan-induced mouse paw oedema is biphasic, age-weight dependent and displays differential nitric oxide cyclooxygenase-2 expression[J]. Br J Pharmacol,2004:142,331. (Pubitemid 38746169)
26. Romano M, Faggioni R, Sironi M, et al. Carrageenan-induced acute inflammation in the mouse air pouch synovial model, role of tumour necrosis factor[J]. Mediators Inflamm,1997,6:32. (Pubitemid 27102180)