The role of pediatricians in families with a history of familial adenomatous polyposis

Clinical Pediatrics

Volumn 48, Issue 6, 2009, Pages 623-626

  Augustyn, Ann Marie ^a   Wallerstein, Robert ^b  

^a LEHIGH VALLEY HOSPITAL   (United States)

^b SANTA CLARA VALLEY MEDICAL CENTER   (United States)

Author keywords

Adenomatous polyposis coli; Familial adenomatous polyposis; Hepatoblastoma; Medulloblastoma; Pediatric; Polyposis; Surveillance

Indexed keywords

APC PROTEIN;

ADENOMATOUS POLYP; ANAMNESIS; ARTICLE; CANCER SCREENING; CASE REPORT; CHILD; CLINICAL FEATURE; COLON CANCER; COLONOSCOPY; FAMILIAL DISEASE; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GENETIC COUNSELING; HEPATOBLASTOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MEDULLOBLASTOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT EDUCATION; PEDIATRICIAN; PRESCHOOL CHILD; SCHOOL CHILD;

ADENOMATOUS POLYPOSIS COLI; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; EXONS; FEMALE; HUMANS; MALE; MEDULLOBLASTOMA; PATIENT EDUCATION AS TOPIC; PEDIGREE; PHYSICIAN'S ROLE; POINT MUTATION; TREATMENT OUTCOME;

EID: 67249135398     PISSN: 00099228     EISSN: None     Source Type: Journal    
DOI: 10.1177/0009922809332681     Document Type: Article

References (14)

1. Bisgaard ML, Fenger K., Bulow S., Niebuhr E., Mohr J. Familial adenomatous polyposis (FAP): frequency, penetrance, and mutation rate. Hum Mutat. 1994 ; 3: 121-125. (Pubitemid 24077228)
2. Winawer S., Fletcher R., Rex D., et al. Colorectal cancer screening and surveillance: clinical guidelines andrationale-update based on new evidence. Gastroenterology. 2003 ; 123: 544-560. (Pubitemid 36169269)
3. Giardiello FM, Brensinger JD, Petersen GM AGA technical review on hereditary colorectal cancer and genetic testing. Gastroenterology. 2001 ; 121: 198-213. (Pubitemid 32591530)
4. Hamilton SR, Liu B., Parsons RE, et al. The molecular basis of Turcot's syndrome. N Engl J Med. 1995 ; 332: 839-847.
5. Leppert M., Dobbs M., Scambler P., et al. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science. 1987 ; 238: 1411-1413. (Pubitemid 18015963)
6. Kinzler KW, Nilbert MC, Vogelstein B., et al. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science. 1991 ; 251: 1366-1370. (Pubitemid 21916922)
7. Thomas D., Pritchard J., Davidson R., McKiernan P., Grundy RG, de Ville de Goyet J. Familial hepatoblastoma and APC gene mutations: renewed call for molecular research. Eur J Cancer. 2003 ; 39: 2200-2204. (Pubitemid 37297746)
8. Attard TM, Giglio P., Koppula S., Snyder C., Lynch HT Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis. Cancer. 2007 ; 109: 761-766. (Pubitemid 46233238)
9. Lynch HT, Smyrk TC Classification of familial adenomatous polyposis: a diagnostic nightmare. Am J HumGenet. 1998 ; 62: 1288-1289. (Pubitemid 28307097)
10. Turcot J., Despres JP, St Pierre F. Malignant tumors of the central nervous system associated with familial polyposis of the colon: report of two cases. Dis Colon Rectum. 1959 ; 2: 465-468.
11. Sanders RP, Furman WL Familial adenomatous polyposis in two brothers with hepatoblastoma: implications for diagnosis and screening. Pediatr Blood Cancer. 2006 ; 47: 851-854. (Pubitemid 44476767)
12. American Gastroenterological Association. American Gastroenterological Association medical position statement: hereditary colorectal cancer and genetic testing. Gastroenterology. 2001 ; 121: 195-197.
13. King JE, Dozois RR, Lindor NM, Ahlquist DA Care of patients and their families with familial adenomatous polyposis. Mayo Clin Proc. 2000 ; 75: 56-67.
14. Attard TM, Tajouri T., Peterson KD, Tinley S., Thorson AG, Lynch HT Familial adenomatous polyposis in children younger than age ten years: a multidisciplinary clinic experience. Dis Colon Rectum. 2008 ; 51: 207-212.