Heart rate response determines long term exercise capacity after heart transplantation

Swiss Medical Weekly

Volumn 139, Issue 21-22, 2009, Pages 308-312

  Käser, Ariane ^a   Martinelli, Michele ^a   Feller, Martin ^b   Carrel, Thierry ^a   Mohacsi, Paul ^a   Hullin, Roger ^a,c  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Exercise capacity; Heart rate; Heart transplantation

Indexed keywords

AMLODIPINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; AGE; ARTICLE; BODY MASS; CARDIAC GRAFT REJECTION; CHRONOTROPISM; CLINICAL ASSESSMENT; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; DIURETIC THERAPY; DYSLIPIDEMIA; EXERCISE; EXERCISE TEST; FEMALE; GENDER; GRAFT RECIPIENT; HEART CATHETERIZATION; HEART FAILURE; HEART GRAFT; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART OUTPUT; HEART RATE; HEART RIGHT VENTRICLE FAILURE; HEART TRANSPLANTATION; HEMODYNAMIC PARAMETERS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LUNG VASCULAR RESISTANCE; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; ORGAN DONOR; POSTOPERATIVE PERIOD; PREDICTIVE VALIDITY; SYSTOLIC BLOOD PRESSURE; TREADMILL EXERCISE;

EID: 67249105352     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Barnard CN. The operation. A human cardiac transplant: an interim report of a successful operation performed at Groote Schuur Hospital, Cape Town. S Afr Med J. 1967;41:1271-1274
2. Wahl A, Feller M, Wigger E, et al. Late normalisation of cardiac allograft right ventricular function in recipients with reversible pulmonary hypertension. Submitted 2008.
3. Grady KL. Quality of life after heart transplantation: are things really better? Curr Opin Cardiol. 2003;18:129-135
4. Grieco A, Long CJ. Investigation of the Karnofsky Performance Status as a measure of quality of life. Health Psychol. 1984;3:129-142
5. Stevenson LW, Sietsema K, Tillisch JH, et al. Exercise capacity for survivors of cardiac transplantation or sustained medical therapy for stable heart failure. Circulation. 1990;81:78-85. (Pubitemid 20031770)
6. Savin WM, Haskell WL, Schroeder JS, Stinson EB. Cardiorespiratory responses of cardiac transplant patients to graded, symptom- limited exercise. Circulation. 1980;62:55-60. (Pubitemid 10083097)
7. Osada N, Chaitman BR, Donohue TJ, Wolford TL, Stelken AM, Miller LW. Long-term cardiopulmonary exercise performance after heart transplantation. Am J Cardiol. 1997;79:451-456 (Pubitemid 127440411)
8. Labovitz AJ, Drimmer AM, McBride LR, Pennington DG, Willman VL, Miller LW. Exercise capacity during the first year after cardiac transplantation. Am J Cardiol. 1989;64:642-645 (Pubitemid 19230236)
9. Mandak JS, Aaronson KD, Mancini DM. Serial assessment of exercise capacity after heart transplantation. J Heart Lung Transplant. 1995;14:468-478
10. Kao AC, Van Trigt P, 3rd, Shaeffer-McCall GS, et al. Central and peripheral limitations to upright exercise in untrained cardiac transplant recipients. Circulation. 1994;89:2605-2615
11. Daida H, Squires RW, Allison TG, Johnson BD, Gau GT. Sequential assessment of exercise tolerance in heart transplantation compared with coronary artery bypass surgery after phase II cardiac rehabilitation. Am J Cardiol. 1996;77:696-700. (Pubitemid 26116683)
12. Marconi C, Marzorati M, Fiocchi R, et al. Age-related heart rate response to exercise in heart transplant recipients. Functional significance. Pflugers Arch. 2002;443:698-706.
13. Gullestad L, Myers J, Edvardsen T, Kjekshus J, Geiran O, Simonsen S. Predictors of exercise capacity and the impact of angiographic coronary artery disease in heart transplant recipients. Am Heart J. 2004;147:49-54. (Pubitemid 38037396)
14. Kapp C. Heart transplant recipient climbs the Matterhorn. 42-year-old Kelly Perkins becomes the first person with a heart transplant to ascend the 4478-m peak. Lancet. 2003;362:880-881
15. Andreassen AK. Point:Counterpoint: Cardiac denervation does/does not play a major role in exercise limitation after heart transplantation. J Appl Physiol. 2008;104:559-560
16. Bristow MR. The surgically denervated, transplanted human heart. Circulation. 1990;82:658-660 (Pubitemid 20257852)
17. Lord SW, Brady S, Holt ND, Mitchell L, Dark JH, McComb JM. Exercise response after cardiac transplantation: correlation with sympathetic reinnervation. Heart. 1996;75:40-43 (Pubitemid 26058454)
18. Pope SE, Stinson EB, Daughters GT, 2nd, Schroeder JS, Ingels NB Jr, Alderman EL. Exercise response of the denervated heart in long-term cardiac transplant recipients. Am J Cardiol. 1980;46:213-218
19. Roten L, Schmid J-P, Merz F, Carrel T, Walpoth N, Mohacsi P, Hullin R. Diastolic dysfunction of the cardiac allograft and maximal exercise capacity. J Heart Lung Transplant. 2009, accepted.
20. Stratton JR, Kemp GJ, Daly RC, Yacoub M, Rajagopalan B. Effects of cardiac transplantation on bioenergetic abnormalities of skeletal muscle in congestive heart failure. Circulation. 1994;89:1624-1631 (Pubitemid 24114240)
21. Lampert E, Mettauer B, Hoppeler H, Charloux A, Charpentier A, Lonsdorfer J. Structure of skeletal muscle in heart transplant recipients. J Am Coll Cardiol. 1996;28:980-984 (Pubitemid 26348165)
22. Schaufelberger M, Eriksson BO, Lonn L, Rundqvist B, Sunnerhagen KS, Swedberg K. Skeletal muscle characteristics, muscle strength and thigh muscle area in patients before and after cardiac transplantation. Eur J Heart Fail. 2001;3:59-67. (Pubitemid 32127111)
23. Kobashigawa JA, Leaf DA, Lee NT, Gleeson MP, Lui HH, Hamilton MA, et al. A controlled trial of exercise rehabilitation after heart transplantation. N Engl J Med. 1999;340:272-277 (Pubitemid 29063269)
24. Leung TC, Ballman KV, Allison TG, et al. Clinical predictors of exercise capacity 1 year after cardiac transplantation. J Heart Lung Transplant. 2003;22:16-27. (Pubitemid 36071413)
25. Givertz MM, Hartley LH, Colucci WS. Long-term sequential changes in exercise capacity and chronotropic responsiveness after cardiac transplantation. Circulation. 1997;96:232-237 (Pubitemid 27298426)
26. Renlund DG, Taylor DO, Ensley RD, et al. Exercise capacity after heart transplantation: influence of donor and recipient characteristics. J Heart Lung Transplant. 1996;15:16-24. (Pubitemid 26056120)
27. Douard H, Parrens E, Billes MA, Labbe L, Baudet E, Broustet JP. Predictive factors of maximal aerobic capacity after cardiac transplantation. Eur Heart J. 1997;18:1823-1828 (Pubitemid 27477939)
28. Stinson EB, Griepp RB, Schroeder JS, Dong E Jr, Shumway NE. Hemodynamic observations one and two years after cardiac transplantation in man. Circulation. 1972;45:1183-1194
29. Scott CD, Dark JH, McComb JM. Evolution of the chronotropic response to exercise after cardiac transplantation. Am J Cardiol. 1995;76:1292-1296
30. Taylor DO, Edwards LB, Boucek MM, et al. Registry of the International Society for Heart and Lung Transplantation: twentyfourth official adult heart transplant report - 2007. J Heart Lung Transplant. 2007;26:769-781 (Pubitemid 47199081)