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Volumn 20, Issue 6, 2009, Pages 450-460

Inhibition of functional HER family members increases the sensitivity to docetaxel in human ovarian cancer cell lines

Author keywords

Cetuximab; Docetaxel; Human epidermal growth factor family; Ovarian cancer; Pertuzumab; Trastuzumab

Indexed keywords

CASPASE 3; CETUXIMAB; DOCETAXEL; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; NEU DIFFERENTIATION FACTOR; PERTUZUMAB; TRASTUZUMAB;

EID: 67249098554     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32832afc24     Document Type: Article
Times cited : (28)

References (46)
  • 1
    • 33745728898 scopus 로고    scopus 로고
    • Challenges for chemotherapy in ovarian cancer
    • DOI 10.1093/annonc/mdj978
    • Ozols RF. Challenges for chemotherapy in ovarian cancer. Ann Oncol 2006; 17(Suppl5):v181-v187. (Pubitemid 43994856)
    • (2006) Annals of Oncology , vol.17 , Issue.SUPPL. 5
    • Ozols, R.F.1
  • 3
    • 1242338152 scopus 로고    scopus 로고
    • The HER receptor family: A rich target for therapeutic development
    • DOI 10.1016/j.ijrobp.2003.09.093
    • Mass RD. The HER receptor family: a rich target for therapeutic development. Int J Radiat Oncol Biol Phys 2004; 58:932-940. (Pubitemid 38221153)
    • (2004) International Journal of Radiation Oncology Biology Physics , vol.58 , Issue.3 , pp. 932-940
    • Mass, R.D.1
  • 4
    • 41949100690 scopus 로고    scopus 로고
    • Clinical implications of the ErbB/epidermal growth factor (EGF) receptor family and its ligands in ovarian cancer
    • Lafky JM, Wilken JA, Baron AT, Maihle NJ. Clinical implications of the ErbB/epidermal growth factor (EGF) receptor family and its ligands in ovarian cancer. Biochim Biophys Acta 2008; 1785:232-265.
    • (2008) Biochim Biophys Acta , vol.1785 , pp. 232-265
    • Lafky, J.M.1    Wilken, J.A.2    Baron, A.T.3    Maihle, N.J.4
  • 5
    • 33749316418 scopus 로고    scopus 로고
    • The epidermal growth factor receptor pathway: A model for targeted therapy
    • DOI 10.1158/1078-0432.CCR-05-1554
    • Scaltriti M, Baselga J. The epidermal growth factor receptor pathway: a model for targeted therapy. Clin Cancer Res 2006; 12:5268-5272. (Pubitemid 44497237)
    • (2006) Clinical Cancer Research , vol.12 , Issue.18 , pp. 5268-5272
    • Scaltriti, M.1    Baselga, J.2
  • 8
    • 0742307268 scopus 로고    scopus 로고
    • In vitro chemoresistance and biomarker profiles are unique for histologic subtypes of epithelial ovarian cancer
    • DOI 10.1016/j.ygyno.2003.09.030
    • Cloven NG, Kyshtoobayeva A, Burger RA, Yu IR, Fruehauf JP. In vitro chemoresistance and biomarker profiles are unique for histologic subtypes of epithelial ovarian cancer. Gynecol Oncol 2004; 92:160-166. (Pubitemid 38147385)
    • (2004) Gynecologic Oncology , vol.92 , Issue.1 , pp. 160-166
    • Cloven, N.G.1    Kyshtoobayeva, A.2    Burger, R.A.3    Yu, I.-R.4    Fruehauf, J.P.5
  • 9
    • 10044232731 scopus 로고    scopus 로고
    • Prognostic significance of p53, Her-2, and EGFR overexpression in borderline and epithelial ovarian cancer
    • DOI 10.1111/j.1048-891X.2004.14606.x
    • Nielsen JS, Jakobsen E, Hølund B, Bertelsen K, Jakobsen A. Prognostic significance of p53, Her-2, and EGFR overexpression in borderline and epithelial ovarian cancer. Int J Gynecol Cancer 2004; 14:1086-1096. (Pubitemid 39603351)
    • (2004) International Journal of Gynecological Cancer , vol.14 , Issue.6 , pp. 1086-1096
    • Nielsen, J.S.1    Jakobsen, E.2    Holund, B.3    Bertelsen, K.4    Jakobsen, A.5
  • 11
    • 33645322927 scopus 로고    scopus 로고
    • Epithelial growth factor receptor status in primary and recurrent ovarian cancer
    • Stadlmann S, Gueth U, Reiser U, Diener PA, Zeimet AG, Wight E, et al. Epithelial growth factor receptor status in primary and recurrent ovarian cancer. Mod Pathol 2006; 19:607-610.
    • (2006) Mod Pathol , vol.19 , pp. 607-610
    • Stadlmann, S.1    Gueth, U.2    Reiser, U.3    Diener, P.A.4    Zeimet, A.G.5    Wight, E.6
  • 12
    • 34548693895 scopus 로고    scopus 로고
    • Prognostic impact of KI67, p53, human epithelial growth factor receptor 2, topoisomerase IIα, epidermal growth factor receptor, and nm23 expression of ovarian carcinomas and disseminated tumor cells in the bone marrow
    • DOI 10.1111/j.1525-1438.2007.00920.x
    • Schindlbeck C, Hantschmann P, Zerzer M, Jahns B, Rjosk D, Janni W, et al. Prognostic impact of Ki67, p53, human epithelial growth factor receptor 2, topoisomerase IIα, epidermal growth factor receptor, and nm23 expression of ovarian carcinomas and disseminated cells in the bone marrow. Int J Gynecol Cancer 2007; 17:1047-1055. (Pubitemid 47414831)
    • (2007) International Journal of Gynecological Cancer , vol.17 , Issue.5 , pp. 1047-1055
    • Schindlbeck, C.1    Hantschmann, P.2    Zerzer, M.3    Jahns, B.4    Rjosk, D.5    Janni, W.6    Rack, B.7    Sommer, H.8    Friese, K.9
  • 13
    • 40749101689 scopus 로고    scopus 로고
    • Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers
    • Vermeij J, Teugels E, Bourgain C, Ziangming J, In't Veld P, Ghislain V, et al. Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers. BMC Cancer 2008; 8:3.
    • (2008) BMC Cancer , vol.8 , pp. 3
    • Vermeij, J.1    Teugels, E.2    Bourgain, C.3    Ziangming, J.4    In't Veld, P.5    Ghislain, V.6
  • 18
    • 33746485766 scopus 로고    scopus 로고
    • Epidermal Growth Factor Receptor Targeting in Cancer
    • DOI 10.1053/j.seminoncol.2006.04.003, PII S0093775406001771
    • Mendelsohn J, Baselga J. Epidermal growth factor receptor targeting in cancer. Sem Oncol 2006; 33:369-385. (Pubitemid 44142736)
    • (2006) Seminars in Oncology , vol.33 , Issue.4 , pp. 369-385
    • Mendelsohn, J.1    Baselga, J.2
  • 19
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab - Mechanism of action and use in clinical practice
    • DOI 10.1056/NEJMra043186
    • Hudis CA. Trastuzumab - mechanism of action and use in clinical practice. New Engl J Med 2007; 357:39-51. (Pubitemid 47026733)
    • (2007) New England Journal of Medicine , vol.357 , Issue.1 , pp. 39-51
    • Hudis, C.A.1
  • 20
    • 1842605531 scopus 로고    scopus 로고
    • Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
    • DOI 10.1016/S1535-6108(04)00083-2, PII S1535610804000832
    • Franklin MC, Carey KD, Vajdos FF, Leahy DJ, De Vos AM, Sliwkowski MX. Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. Cancer Cell 2004; 5:317-328. (Pubitemid 38482068)
    • (2004) Cancer Cell , vol.5 , Issue.4 , pp. 317-328
    • Franklin, M.C.1    Carey, K.D.2    Vajdos, F.F.3    Leahy, D.J.4    De Vos, A.M.5    Sliwkowski, M.X.6
  • 23
    • 17544381841 scopus 로고    scopus 로고
    • Docetaxel in the management of ovarian cancer
    • DOI 10.1586/14737140.5.2.203
    • Blagden SP, Kaye SB. Docetaxel in the management of ovarian cancer. Exp Rev Anticancer Ther 2005; 5:203-214. (Pubitemid 40553087)
    • (2005) Expert Review of Anticancer Therapy , vol.5 , Issue.2 , pp. 203-214
    • Blagden, S.P.1    Kaye, S.B.2
  • 25
    • 0021933379 scopus 로고
    • Comparative properties of five human ovarian adenocarcinoma cell lines
    • Buick RN, Pullano R, Trent JM. Comparative properties of five human ovarian adenocarcinoma cell lines. Cancer Res 1985; 45:3668-3676. (Pubitemid 15226443)
    • (1985) Cancer Research , vol.45 , Issue.8 , pp. 3668-3676
    • Buick, R.N.1    Pullano, R.2    Trent, J.M.3
  • 26
    • 0037085048 scopus 로고    scopus 로고
    • Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel
    • DOI 10.1016/S0006-2952(01)00895-4, PII S0006295201008954
    • Kolfschoten GM, Hulscher TM, Duyndam MCA, Pinedo HM, Boven E. Variation in the kinetics of caspase-3 activation, Bcl-2 phosphorylation and apoptotic morphology in unselected human ovarian cancer cell lines as a response to docetaxel. Biochem Pharmacol 2002; 63:733-743. (Pubitemid 34457705)
    • (2002) Biochemical Pharmacology , vol.63 , Issue.4 , pp. 733-743
    • Kolfschoten, G.M.1    Hulscher, T.M.2    Duyndam, M.C.A.3    Pinedo, H.M.4    Boven, E.5
  • 27
    • 0037108866 scopus 로고    scopus 로고
    • Enhanced sensitization to Taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells
    • Lee S, Yang W, Lan KH, Sellappan S, Klos K, Hortobagyi G, et al. Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells. Cancer Res 2002; 62:5703-5710. (Pubitemid 35204725)
    • (2002) Cancer Research , vol.62 , Issue.20 , pp. 5703-5710
    • Lee, S.1    Yang, W.2    Lan, K.-H.3    Sellappan, S.4    Klos, K.5    Hortobagyi, G.6    Hung, M.-C.7    Yu, D.8
  • 28
    • 1942441770 scopus 로고    scopus 로고
    • Blockade of Epidermal Growth Factor- Or Heregulin-Dependent ErbB2 Activation with the Anti-ErbB2 Monoclonal Antibody 2C4 Has Divergent Downstream Signaling and Growth Effects
    • DOI 10.1158/0008-5472.CAN-03-3106
    • Jackson JG, St Clair P, Sliwkowski MX, Brattain MG. Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects. Cancer Res 2004; 64:2601-2609. (Pubitemid 38523918)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2601-2609
    • Jackson, J.G.1    St Clair, P.2    Sliwkowski, M.X.3    Brattain, M.G.4
  • 29
    • 0037499945 scopus 로고    scopus 로고
    • Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: Limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways
    • Janmaat ML, Kruyt FA, Rodriguez JA, Giaccone G. Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways. Clin Cancer Res 2003; 9:2316-2326. (Pubitemid 36687658)
    • (2003) Clinical Cancer Research , vol.9 , Issue.6 , pp. 2316-2326
    • Janmaat, M.L.1    Kruyt, F.A.E.2    Rodriguez, J.A.3    Giaccone, G.4
  • 30
    • 0028248190 scopus 로고
    • The Bradford method for protein quantitation
    • Kruger NJ. The Bradford method for protein quantitation. Methods Mol Biol 1994; 32:9-15.
    • (1994) Methods Mol Biol , vol.32 , pp. 9-15
    • Kruger, N.J.1
  • 33
    • 33751286693 scopus 로고    scopus 로고
    • Pharmacokinetics of cetuximab after administration of escalating single dosing and weekly fixed dosing in patients with solid tumors
    • DOI 10.1158/1078-0432.CCR-06-0705
    • Tan AR, Moore DF, Hidalgo M, Doroshow JH, Poplin EA, Goodin S, et al. Pharmacokinetics of cetuximab after administration of escalating single dosing and weekly fixed dosing in patients with solid tumors. Clin Cancer Res 2006; 12:6517-6522. (Pubitemid 44799726)
    • (2006) Clinical Cancer Research , vol.12 , Issue.21 , pp. 6517-6522
    • Tan, A.R.1    Moore, D.F.2    Hidalgo, M.3    Doroshow, J.H.4    Poplin, E.A.5    Goodin, S.6    Mauro, D.7    Rubin, E.H.8
  • 34
    • 33745343753 scopus 로고    scopus 로고
    • Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis
    • DOI 10.1007/s11095-006-0205-x
    • Ng CM, Lum BL, Gimenez V, Kelsey S, Allison D. Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis. Pharm Res 2006; 23:1275-1284. (Pubitemid 43946149)
    • (2006) Pharmaceutical Research , vol.23 , Issue.6 , pp. 1275-1284
    • Ng, C.M.1    Lum, B.L.2    Gimenez, V.3    Kelsey, S.4    Allison, D.5
  • 37
    • 40949135397 scopus 로고    scopus 로고
    • PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab
    • Jhawer M, Goel S, Wilson AJ, Montagna C, Ling YH, Byun DS, et al. PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab. Cancer Res 2008; 68:1953-1961.
    • (2008) Cancer Res , vol.68 , pp. 1953-1961
    • Jhawer, M.1    Goel, S.2    Wilson, A.J.3    Montagna, C.4    Ling, Y.H.5    Byun, D.S.6
  • 38
    • 0037229714 scopus 로고    scopus 로고
    • Overexpression of AKT2/protein kinase Bβ leads to up-regulation of β1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells
    • Arboleda MJ, Lyons JF, Kabbinavar FF, Bray MR, Snow BE, Ayala R, et al. Overexpression of AKT2/protein kinase Bβ leads to up-regulation of β1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells. Cancer Res 2003; 63:196-206. (Pubitemid 36070440)
    • (2003) Cancer Research , vol.63 , Issue.1 , pp. 196-206
    • Arboleda, M.J.1    Lyons, J.F.2    Kabbinavar, F.F.3    Bray, M.R.4    Snow, B.E.5    Ayala, R.6    Danino, M.7    Karlan, B.Y.8    Slamon, D.J.9
  • 39
    • 0037440042 scopus 로고    scopus 로고
    • Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the gynecologic oncology group
    • Bookman MA, Darcy KM, Clarke-Pearson D, Boothby RA, Horowitz IR. Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the gynecologic oncology group. J Clin Oncol 2003; 21:283-290.
    • (2003) J Clin Oncol , vol.21 , pp. 283-290
    • Bookman, M.A.1    Darcy, K.M.2    Clarke-Pearson, D.3    Boothby, R.A.4    Horowitz, I.R.5
  • 42
    • 48649092620 scopus 로고    scopus 로고
    • A central role for HER3 in HER2-amplified breast cancer: Implications for targeted therapy
    • Lee-Hoeflich ST, Crocker L, Yao E, Pham T, Munroe X, Hoeflich KP, et al. A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy. Cancer Res 2008; 68:5878-5887.
    • (2008) Cancer Res , vol.68 , pp. 5878-5887
    • Lee-Hoeflich, S.T.1    Crocker, L.2    Yao, E.3    Pham, T.4    Munroe, X.5    Hoeflich, K.P.6
  • 43
    • 34547866682 scopus 로고    scopus 로고
    • Targeting EGFR and HER-2 with cetuximab- And trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma
    • Kawaguchi Y, Kono K, Mimura K, Mitsui F, Sugai H, Akaike H, et al. Targeting EGFR and HER-2 with cetuximab- and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma. Br J Cancer 2007; 97:494-501.
    • (2007) Br J Cancer , vol.97 , pp. 494-501
    • Kawaguchi, Y.1    Kono, K.2    Mimura, K.3    Mitsui, F.4    Sugai, H.5    Akaike, H.6
  • 44
    • 22344457603 scopus 로고    scopus 로고
    • Combination treatment with erlotinib and pertuzumab against human tumor xenografts is superior to monotherapy
    • Friess T, Scheuer W, Hasmann M. Combination treatment with erlotinib and pertuzumab against human tumor xenografts is superior to monotherapy. Clin Cancer Res 2005; 11:5300-5309.
    • (2005) Clin Cancer Res , vol.11 , pp. 5300-5309
    • Friess, T.1    Scheuer, W.2    Hasmann, M.3
  • 45
    • 33846552656 scopus 로고    scopus 로고
    • Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3
    • Sergina NV, Rausch M, Wang D, Blair J, Hann B, Shokat KM, et al. Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3. Nature 2007; 445:437-441.
    • (2007) Nature , vol.445 , pp. 437-441
    • Sergina, N.V.1    Rausch, M.2    Wang, D.3    Blair, J.4    Hann, B.5    Shokat, K.M.6
  • 46
    • 51449112583 scopus 로고    scopus 로고
    • HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells
    • Kong A, Calleja V, Leboucher P, Harris A, Parker PJ, Larijani B. HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells. PLos One 2008; 3:e2881.
    • (2008) PLos One , vol.3
    • Kong, A.1    Calleja, V.2    Leboucher, P.3    Harris, A.4    Parker, P.J.5    Larijani, B.6


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