Low-Cost, multiplexed biosensor for disease diagnosis

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7167, Issue , 2009, Pages

  Myatt, Christopher J ^a   Delaney, Marie ^a   Todorof, Kathryn ^a   Heil, James ^a   Givens, Monique ^a   Schooley, Robert T ^b   Lochhead, Michael J ^a  

^a Precision Photonics Corporation   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fluorescence; Francisella tularensis; HIV; Immunoassay; Infectious disease; Microarray; Microfluidic; Nucleic acid

Indexed keywords

CMOS IMAGERS; CO-INFECTIONS; CONFIRMATORY TEST; COST STRUCTURE; CURRENT DETECTION LIMITS; DETECTION SYSTEM; DISEASE DIAGNOSIS; DISPOSABLE CARTRIDGE; EASE OF USE; FLUORESCENCE TECHNOLOGIES; FRANCISELLA TULARENSIS; GLOBAL HEALTH; HIV; HUMAN SERUM; HUMAN T CELLS; IMMUNOASSAY; INFECTIOUS DISEASE; LATERAL FLOW; LOW COSTS; POINT OF CARE; RAPID TEST; SANDWICH ASSAYS; SENSITIVE DETECTION;

ANTIBODIES; ANTIGENS; BIOMOLECULES; BIOSENSORS; COSTS; DIAGNOSIS; ECONOMIC ANALYSIS; FLUORESCENCE; IMMUNOLOGY; MULTIPLEXING; NANOSENSORS; RNA;

NUCLEIC ACIDS;

EID: 67249094488     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.811129     Document Type: Conference Paper

References (16)

1. Harrick, N.J. and Loeb, G.I., "Multiple Internal Reflection Fluorescence Spectrometry" Anal Chem 45(4), 687-689 (1973).
2. Herron, J.N., Wang, H.-K., Tan, L., Brown, S.Z., Terry, A.H., Durtschi, J.D., Tolley, S.E., Simon, E.M., Astill, M.E., Smith, R.S., and Christensen, D.A., [Fluorescence Sensors and Biosensors] Taylor & Francis CRC Press, Boca Raton, FL, 283-332 (2005).
3. Ives, J. and Reichert, W.M., "Protein Adsorption on the Surface of a Thin-Film Polymer Integrated Optical Waveguide" Appl Spectroscopy 42(1), 68-72 (1988).
4. Sipe, D.M., Schoonmaker, K.P., Herron, J.N., and Mostert, M.J., "Evanescent planar waveguide detection of biological warfare simulants" Proc. SPIE 1913, 215-222 (2000).
5. Tolley, S.E., Wang, H.K., Smith, R.S., Christensen, D.A., and Herron, J.N., "Single-chain polymorphism analysis in long QT syndrome using planar waveguide fluorescent biosensors" Anal Biochem 315(2), 223-237 (2003).
6. Delehanty, J.B. and Ligler, F.S., "A microarray immunoassay for simultaneous detection of proteins and bacteria" Anal Chem 74(21), 5681-5687 (2002).
7. Feldstein, M.J., Golden, J.P., Rowe, C.A., Maccraith, B.D., and Ligler, F.S., "Array biosensor: optical and fluidics systems" Biomed Microdevices 1(2), 139-153 (1999).
8. Rowe, C.A., Tender, L.M., Feldstein, M.J., Golden, J.P., Scruggs, S.B., MacCraith, B.D., Cras, J.J., and Ligler, F.S., "Array biosensor for simultaneous identification of bacterial, viral, and protein analytes" Anal Chem 71(17), 3846-3852 (1999).
9. Stimpson, D.I., Hoijer, J.V., Hsieh, W.T., Jou, C., Gordon, J., Theriault, T., Gamble, R., and Baldeschwieler, J.D., "Real-time detection of DNA hybridization and melting on oligonucleotide arrays by using optical wave guides" Proc Natl Acad Sci U S A 92(14), 6379-6383 (1995).
10. Plowman, T.E., Durstchi, J.D., Wang, H.K., Christensen, D.A., Herron, J.N., and Reichert, W.M., "Multiple-analyte fluoroimmunoassay using an integrated optical waveguide sensor" Anal Chem 71(19), 4344-4352 (1999).
11. Plowman, T.E., Reichert, W.M., Peters, C.R., Wang, H.K., Christensen, D.A., and Herron, J.N., "Femtomolar sensitivity using a channel-etched thin film waveguide fluoroimmunosensor" Biosens Bioelectron 11(1-2), 149-160 (1996).
12. Pawlak, M., Schick, E., Bopp, M.A., Schneider, M.J., Oroszlan, P., and Ehrat, M., "Zeptosens' protein microarrays: a novel high performance microarray platform for low abundance protein analysis" Proteomics 2(4), 383-393 (2002).
13. Benson, C.A., Kaplan, J.E., Masur, H., Pau, A., and Holmes, K.K., "Treating opportunistic infections among HIV-infected adults and adolescents: recommendations from CDC., the National Institutes of Health, and the HIV Medicine Association/Infectious Disease Society of America" MMWR 53(RR-15), 1-112 (2004).
14. Grainger, D.W., Greef, C.H., Gong, P., and Lochhead, M.J., "Current microarray surface chemistries" Methods Mol Biol 381, 37-57 (2007).
15. Fox, G.E., Stackebrandt, E., Hespell, R.B., Gibson, J., Maniloff, J., Dyer, T.A., Wolfe, R.S., Balch, W.E., Tanner, R.S., Magrum, L.J., Zablen, L.B., Blakemore, R., Gupta, R., Bonen, L., Lewis, B.J., Stahl, D.A., Luehrsen, K.R., Chen, K.N., and Woese, C.R., "The phytogeny of prokaryotes" Science 209(4455), 457-463 (1980).
16. St Amand, A.L., Frank, D.N., De Groote, M.A., Basaraba, R.J., Orme, I.M., and Pace, N.R., "Use of specific rRNA oligonucleotide probes for microscopic detection of Mycobacterium tuberculosis in culture and tissue specimens" J Clin Microbiol 43(10), 5369-5371 (2005).