A comparative study on non-confluent and confluent human malignant brain cancer metabolic response to he-ne laser exposures: Evidence for laser enhanced cellular production of H2O2 and laser induced "bystander" effect

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7165, Issue , 2009, Pages

  Tata, Darrell B ^a   Waynant, Ronald W ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN CANCER; CELLULAR PRODUCTION; COMPARATIVE STUDIES; CONTINUOUS WAVE; FLUENCE RANGE; GLIOBLASTOMA CELLS; GROWTH CONDITIONS; GROWTH MEDIA; HE-NE LASERS; LASER EXPOSURE; LASER FLUENCE; LASER INDUCED; LASER IRRADIATIONS; LIGHT IRRADIATIONS; METABOLIC ACTIVITY; MODULATION RESPONSE; NON-IRRADIATED CELLS; POST-EXPOSURE; TREATMENT CONDITIONS;

CELL MEMBRANES; CYTOLOGY; GROWTH KINETICS; HELIUM; IRRADIATION; METABOLISM; MODULATION; NEON; RADIATION DAMAGE;

LASERS;

EID: 67249086213     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.813409     Document Type: Conference Paper

References (10)

1. Hamblin, M. Mechanisms of Low Light Therapy. Proc. SPIE. Vol. 6140, pp 1-12, 2006.
2. Karu, T. Chapter 7: Low Power Laser Effects. In: Lasers in Medicine edited by Ronald W. Waynant, CRC press, N.Y., 2002
3. Tata, D.B., Waynant, R.W. Laser light induced modulations in metabolic activities in human brain cancer. Proc. SPIE, Vol. 6846, pp 7-12, 2008.
4. Karu, T.I. Mitochondrial Signaling in Mammalian Cells Activated by Red and Near-IR Radiation. J. Photochemistry and Photobiology, Vol. 84, pp 1091-1099, 2008.
5. Nulton-Persson, A.C., Szweda, L.I. Modulations of Mitochondrial Function by Hydrogen Peroxide. J. Biological Chem. Vol. 276, pp 23357-23361, 2001.
6. Szatrowski TP, Nathan CF. Production of large amounts of Hydrogen Peroxide by Human Tumor Cells. Cancer Res. Vol. 51, pp. 794-798, 1991.
7. Lubart, R., Lavi R., Friedmann H., Rochkind, S. Photochemistry and Photobiology of Light Absorption by Living Cells. Photomed Laser Surg. Vol. 24, pp. 179-185, 2006
8. Zhou M., Diwu Z., Panchuk-Voloshina N., Haugland R.P. A Stable Non-fluorescent Derivative of Resorufin for the Fluorometric Determination of Trace Hydrogen Peroxide: Applications in Detecting the Activity of Phagocyte NADPH Oxidase and Other Oxidases. Anal Biochem. Vol 253, pp 162-168, 1997.
9. Hamblin, M. The Role of Nitric Oxide in Low Level Light Therapy. Proc. SPIE. Vol. 6846, pp 1-14, 2008.
10. Brookes, P.S., et al. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am. J. Physiol Cell Physiol. Vol 287, pp C 817 - C 833, 2004.