Association of thymidylate synthase variants with 5-fluorouracil cytotoxicity

Pharmacogenetics and Genomics

Volumn 19, Issue 5, 2009, Pages 399-401

  Peters, Eric J ^a,d   Kraja, Aldi T ^a,b   Lin, Shiow J ^b,d   Yen Revollo, Jane L ^a,d   Marsh, Sharon ^c,d   Province, Michael A ^b,d   McLeod, Howard L ^a,d  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b Division of Statistical Genomics

^c Division of Oncology   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 fluorouracil; Centre d'Etude du Polymorphisme Humain cell lines; Thymidylate synthase

Indexed keywords

FLUOROURACIL; THYMIDYLATE SYNTHASE; ANTINEOPLASTIC ANTIMETABOLITE;

ARTICLE; BIOASSAY; CYTOTOXICITY; DRUG BLOOD LEVEL; EX VIVO STUDY; GENE MAPPING; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; NUCLEOTIDE SEQUENCE; PEDIGREE; PHARMACOGENETICS; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; DRUG SCREENING; DRUG TOXICITY; GENETICS; PHYSIOLOGY; TUMOR CELL LINE; VALIDATION STUDY;

ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG TOXICITY; FLUOROURACIL; HUMANS; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; THYMIDYLATE SYNTHASE;

EID: 67149114893     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e328329fdec     Document Type: Article

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