Influence of computer-aided detection false-positives on reader performance and diagnostic confidence for CT colonography

American Journal of Roentgenology

Volumn 192, Issue 6, 2009, Pages 1682-1689

  Taylor, Stuart A ^a   Brittenden, John ^b   Lenton, James ^c   Lambie, Hannah ^c   Goldstone, Anthony ^c   Wylie, Peter N ^d   Tolan, Damian ^c   Burling, David ^d   Honeyfield, Leslie ^e   Bassett, Paul ^f   Halligan, Steve ^a  

^a UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

^b PINDERFIELDS GENERAL HOSPITAL   (United Kingdom)

^c LEEDS GENERAL INFIRMARY   (United Kingdom)

^d ST MARK S HOSPITAL   (United Kingdom)

^e Medicsight PLC   (United Kingdom)

^f Statistical Consultancy   (United Kingdom)

Author keywords

Colorectal cancer; Computer aided detection; CT colonography; Screening

Indexed keywords

AGED; ARTICLE; COMPUTED TOMOGRAPHIC COLONOGRAPHY; COMPUTER ASSISTED DIAGNOSIS; DIAGNOSTIC VALUE; FALSE POSITIVE RESULT; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYP; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; ALGORITHM; ARTIFICIAL INTELLIGENCE; AUTOMATED PATTERN RECOGNITION; COLON POLYP; EVALUATION; HEALTH PERSONNEL ATTITUDE; IMAGE QUALITY; LABORATORY DIAGNOSIS; METHODOLOGY; OBSERVER VARIATION; RADIOGRAPHY; REPRODUCIBILITY;

AGED; ALGORITHMS; ARTIFICIAL INTELLIGENCE; ATTITUDE OF HEALTH PERSONNEL; COLONIC POLYPS; COLONOGRAPHY, COMPUTED TOMOGRAPHIC; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; MALE; OBSERVER VARIATION; PATTERN RECOGNITION, AUTOMATED; RADIOGRAPHIC IMAGE ENHANCEMENT; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 67049172135     PISSN: 0361803X     EISSN: None     Source Type: Journal    
DOI: 10.2214/AJR.08.1625     Document Type: Article

References (25)

1. Yoshida H, Dachman AH. Computer-aided diagnosis for CT colonography. Semin Ultrasound CT MR 2004; 25:419-431 (Pubitemid 39424005)
2. Taylor SA, Halligan S, Burling D, et al. Computer-assisted reader software versus expert reviewers for polyp detection on CT colonography. AJR 2006; 186:696-702 (Pubitemid 46100255)
3. Mang T, Peloschek P, Plank C, et al. Effect of computer-aided detection as a second reader in multidetector-row CT colonography. Eur Radiol 2007; 17:2598-2607
4. Baker ME, Bogoni L, Obuchowski NA, et al. Computer-aided detection of colorectal polyps: can it improve sensitivity of less-experienced readers? Preliminary findings. Radiology 2007; 245:140-149 (Pubitemid 47417797)
5. Dehmeshki J, Halligan S, Taylor SA, et al. Computer assisted detection software for CT colonography: effect of sphericity filter on performance characteristics for patients with and without fecal tagging. Eur Radiol 2007; 17:662-668 (Pubitemid 46252344)
6. Halligan S, Taylor SA, Dehmeshki J, et al. Computer-assisted detection for CT colonography: external validation. Clin Radiol 2006; 61:758-763 (Pubitemid 44184731)
7. Petrick N, Haider M, Summers RM, et al. CT colonography with computer-aided detection as a second reader: observer performance study. Radiology 2008; 246:148-156 [Erratum in Radiology 2008; 248:704] (Pubitemid 350305038)
8. Yoshida H, Dachman AH. CAD techniques, challenges, and controversies in computed tomographic colonography. Abdom Imaging 2005; 30:26-41 (Pubitemid 40169505)
9. Taylor SA, Greenhalgh R, Ilangovan R, et al. CT colonography and computer-aided detection: effect of false-positive results on reader specificity and reading efficiency in a low-prevalence screening population. Radiology 2008; 247:133-140
10. Suzuki K, Yoshida H, Nappi J, Armato SG III, Dachman AH. Mixture of expert 3D massive-training ANNs for reduction of multiple types of false positives in CAD for detection of polyps in CT colonography. Med Phys 2008; 35:694-703 (Pubitemid 351190889)
11. Suzuki K, Yoshida H, Nappi J, Dachman AH. Massive-training artificial neural network (MTANN) for reduction of false positives in computer-aided detection of polyps: suppression of rectal tubes. Med Phys 2006; 33:3814-3824 (Pubitemid 44505106)
12. O'Connor SD, Summers RM, Yao J, Pickhardt PJ, Choi JR. CT colonography with computer-aided polyp detection: volume and attenuation thresholds to reduce false-positive findings owing to the ileocecal valve. Radiology 2006; 241:426-432
13. Wang S, Yao J, Summers RM. Improved classifier for computer-aided polyp detection in CT colonography by nonlinear dimensionality reduction. Med Phys 2008; 35:1377-1386
14. Wang Z, Liang Z, Li L, et al. Reduction of false positives by internal features for polyp detection in CT-based virtual colonoscopy. Med Phys 2005; 32:3602-3616
15. Nappi J, Yoshida H. Feature-guided analysis for reduction of false positives in CAD of polyps for computed tomographic colonography. Med Phys 2003; 30:1592-1601 (Pubitemid 36885777)
16. Nappi J, Yoshida H. Fully automated three-dimensional detection of polyps in fecal-tagging CT colonography. Acad Radiol 2007; 14:287-300 (Pubitemid 46331875)
17. Summers RM, Yao J, Pickhardt PJ, et al. Computed tomographic virtual colonoscopy computer-aided polyp detection in a screening population. Gastroenterology 2005; 129:1832-1844 (Pubitemid 41772962)
18. Fletcher JG, Booya F, Summers RM, et al. Comparative performance of two polyp detection systems on CT colonography. AJR 2007; 189:277-282 (Pubitemid 47195910)
19. Taylor SA, Iinuma G, Saito Y, Zhang J, Halligan S. CT colonography: computer-aided detection of morphologically flat T1 colonic carcinoma. Eur Radiol 2008; 18:1666-1673
20. Taylor SA, Suzuki N, Beddoe G, Halligan S. Flat neoplasia of the colon: CT colonography with CAD. Abdom Imaging 2008 May 30 [Epub ahead of print]
21. Taylor SA, Halligan S, Burling D, et al. CT colonography: effect of experience and training on reader performance. Eur Radiol 2004; 14:39-43 (Pubitemid 38787248)
22. Zalis ME, Barish MA, Choi JR, et al. CT colonography reporting and data system: a consensus proposal. Radiology 2005; 236:3-9 (Pubitemid 40853289)
23. Soto JA, Barish MA, Yee J. Reader training in CT colonography: how much is enough? Radiology 2005; 237:26-27 (Pubitemid 41346142)
24. Pickhardt PJ, Choi JR, Hwang I, et al. Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 2003; 349:2191-2200 (Pubitemid 37485135)
25. Toledano AY, Chen M, Johnson CD, Heiken JP. Accuracy of primary 2D and primary 3D review of CT colonography examinations in National CT Colonography Trial conducted by American College of Radiology Imaging Network (ACRIN). (abstr) In: Radiological Society of North America assembly and annual meeting program. Oak Brook, IL: RSNA, 2007