-
1
-
-
0037313263
-
Creation of a zymogen
-
Plainkum, P., Fuchs, S. M., Wiyakrutta, S., and Raines, R. T. (2003) Creation of a zymogen. Nat. Struct. Biol.10, 115-119.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 115-119
-
-
Plainkum, P.1
Fuchs, S.M.2
Wiyakrutta, S.3
Raines, R.T.4
-
2
-
-
27344444248
-
Ribonuclease inhibitor: Structure and function
-
Dickson,K. A., Haigis, M. C., and Raines, R. T. (2005) Ribonuclease inhibitor: Structure and function. Prog. Nucleic Acid Res. Mol. Biol.80, 349-374.
-
(2005)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.80
, pp. 349-374
-
-
Dickson, K.A.1
Haigis, M.C.2
Raines, R.T.3
-
3
-
-
0024496381
-
Tight-binding inhibition of angiogenin and ribonuclease a by placental ribonuclease inhibitor
-
DOI 10.1021/bi00427a031
-
Lee, F. S., Shapiro, R., and Vallee, B. L. (1989) Tight-binding inhibition of angiogenin and ribonucleaseAby placental ribonuclease inhibitor. Biochemistry28, 225-230. (Pubitemid 19046737)
-
(1989)
Biochemistry
, vol.28
, Issue.1
, pp. 225-230
-
-
Lee, F.S.1
Shapiro, R.2
Vallee, B.L.3
-
4
-
-
0025006582
-
Protein chemical and kinetic characterization of recombinant porcine ribonuclease inhibitor expressed in Saccharomyces cerevisiae
-
DOI 10.1021/bi00489a046
-
Vicentini, A. M., Kieffer, B., Matthies, R., Meyhack, B., Hemmings, B. A., Stone, S. R., and Hofsteenge, J. (1990) Protein chemical and kinetic characterization of recombinant porcine ribonuclease inhibitor expressed in Saccharomyces cerevisiae. Biochemistry29, 8827-8834. (Pubitemid 20302782)
-
(1990)
Biochemistry
, vol.29
, Issue.37
, pp. 8827-8834
-
-
Vicentini, A.M.1
Kieffer, B.2
Matthies, R.3
Meyhack, B.4
Hemmings, B.A.5
Stone, S.R.6
Hofsteenge, J.7
-
5
-
-
33947598165
-
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein
-
Johnson, R. J., McCoy, J. G., Bingman, C. A., Phillips, G. N.Jr., and Raines, R. T. (2007) Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. J. Mol. Biol.367, 434-449.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 434-449
-
-
Johnson, R.J.1
McCoy, J.G.2
Bingman, C.A.3
Phillips Jr., G.N.4
Raines, R.T.5
-
6
-
-
36048943980
-
Intraspecies regulation of ribonucleolytic activity
-
DOI 10.1021/bi701521q
-
Johnson, R. J., Lavis, L. D., and Raines, R. T. (2007) Intraspecies regulation of ribonucleolytic activity. Biochemistry46, 13131-13140. (Pubitemid 350086231)
-
(2007)
Biochemistry
, vol.46
, Issue.45
, pp. 13131-13140
-
-
Johnson, R.J.1
Lavis, L.D.2
Raines, R.T.3
-
7
-
-
54049094773
-
Cytotoxic ribonuclease onconase targets RNA interference (siRNA)
-
Zhao, H., Ardelt, B., Ardelt, W., Shogen, K., and Darzynkiewicz, Z. (2008) Cytotoxic ribonuclease onconase targets RNA interference (siRNA). Cell Cycle7, 3258-3261.
-
(2008)
Cell Cycle
, vol.7
, pp. 3258-3261
-
-
Zhao, H.1
Ardelt, B.2
Ardelt, W.3
Shogen, K.4
Darzynkiewicz, Z.5
-
8
-
-
0029006175
-
Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities
-
Kim, J.-S., Souček, J., Matoušek, J., and Raines, R. T. (1995) Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities. Biochem. J.308, 547-550.
-
(1995)
Biochem. J.
, vol.308
, pp. 547-550
-
-
Kim, J.-S.1
Souček, J.2
Matoušek, J.3
Raines, R.T.4
-
9
-
-
0028911034
-
A structural basis of the interactions between leucine-rich repeats and protein ligands
-
Kobe, B., and Deisenhofer, J. (1995) A structural basis of the interactions between leucine-rich repeats and protein ligands. Nature374, 183-186.
-
(1995)
Nature
, vol.374
, pp. 183-186
-
-
Kobe, B.1
Deisenhofer, J.2
-
10
-
-
0027256672
-
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity
-
Wu, Y., Mikulski, S. M., Ardelt, W., Rybak, S. M., and Youle, R. J. (1993) A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity. J. Biol. Chem.268, 10686-10693.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10686-10693
-
-
Wu, Y.1
Mikulski, S.M.2
Ardelt, W.3
Rybak, S.M.4
Youle, R.J.5
-
11
-
-
55549133584
-
Interaction of onconase with the human ribonuclease inhibitor protein
-
Turcotte, R. F., and Raines, R. T. (2008) Interaction of onconase with the human ribonuclease inhibitor protein. Biochem. Biophys. Res. Commun.377, 512-514.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 512-514
-
-
Turcotte, R.F.1
Raines, R.T.2
-
12
-
-
38549168927
-
Ribonucleases as novel chemotherapeutics: The ranpirnase example
-
Lee, J. E., and Raines, R. T. (2008) Ribonucleases as novel chemotherapeutics: The ranpirnase example. BioDrugs22, 53-58. (Pubitemid 351158535)
-
(2008)
BioDrugs
, vol.22
, Issue.1
, pp. 53-58
-
-
Lee, J.E.1
Raines, R.T.2
-
13
-
-
47749087053
-
Onconase and Amphinase, the antitumor ribonucleases from Rana pipiens oocytes
-
Ardelt, W., Shogen, K., and Darzynkiewicz, Z. (2008) Onconase and Amphinase, the antitumor ribonucleases from Rana pipiens oocytes. Curr. Pharm. Biotechnol.9, 215-225.
-
(2008)
Curr. Pharm. Biotechnol.
, vol.9
, pp. 215-225
-
-
Ardelt, W.1
Shogen, K.2
Darzynkiewicz, Z.3
-
14
-
-
0032169863
-
Ribonuclease A variants with potent cytotoxic activity
-
Leland, P. A., Schultz, L. W., Kim, B.-M., and Raines, R. T. (1998) Ribonuclease A variants with potent cytotoxic activity. Proc. Natl. Acad. Sci. U.S.A.98, 10407-10412.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 10407-10412
-
-
Leland, P.A.1
Schultz, L.W.2
Kim, B.-M.3
Raines, R.T.4
-
15
-
-
27344441004
-
Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A
-
Rutkoski, T. J., Kurten, E. L., Mitchell, J. C., and Raines, R. T. (2005) Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A. J. Mol. Biol.354, 41-54.
-
(2005)
J. Mol. Biol.
, vol.354
, pp. 41-54
-
-
Rutkoski, T.J.1
Kurten, E.L.2
Mitchell, J.C.3
Raines, R.T.4
-
16
-
-
0035900671
-
Endowing human pancreatic ribonuclease with toxicity for cancer cells
-
Leland, P. A., Staniszewski, K. E., Kim, B.-M., and Raines, R. T. (2001) Endowing human pancreatic ribonuclease with toxicity for cancer cells. J. Biol. Chem.276, 43095-43102.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43095-43102
-
-
Leland, P.A.1
Staniszewski, K.E.2
Kim, B.-M.3
Raines, R.T.4
-
17
-
-
47749114193
-
Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity
-
Rutkoski, T. J., and Raines, R. T. (2008) Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity. Curr. Pharm. Biotechnol.9, 185-189.
-
(2008)
Curr. Pharm. Biotechnol.
, vol.9
, pp. 185-189
-
-
Rutkoski, T.J.1
Raines, R.T.2
-
18
-
-
0034615926
-
A ribonuclease A variant with low catalytic activity but high cytotoxicity
-
Bretscher, L. E., Abel, R. L., and Raines, R. T. (2000) A ribonuclease A variant with low catalytic activity but high cytotoxicity. J. Biol. Chem.275, 9893-9896.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9893-9896
-
-
Bretscher, L.E.1
Abel, R.L.2
Raines, R.T.3
-
19
-
-
0038723718
-
Compensating effects on the cytotoxicity of ribonuclease A variants
-
Dickson, K. A., Dahlberg, C. L., and Raines, R. T. (2003) Compensating effects on the cytotoxicity of ribonuclease A variants. Arch. Biochem. Biophys.415, 172-177.
-
(2003)
Arch. Biochem. Biophys.
, vol.415
, pp. 172-177
-
-
Dickson, K.A.1
Dahlberg, C.L.2
Raines, R.T.3
-
20
-
-
4544330800
-
Cytosolic RNase inhibitor only affects RNases with intrinsic cytotoxicity
-
Monti, D. M., and D'Alessio, G. (2004) Cytosolic RNase inhibitor only affects RNases with intrinsic cytotoxicity. J. Biol. Chem.279, 39195-39198.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 39195-39198
-
-
Monti, D.M.1
D'Alessio, G.2
-
21
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
DOI 10.1038/35078107
-
Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature411, 494-498. (Pubitemid 32494397)
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
22
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen, N. J., Parrish, S., Imani, F., Fire, A., and Morgan, R. A. (2001) Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. U.S.A.98, 9742-9747.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
23
-
-
10744219688
-
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
-
Scacheri, P. C., Rozenblatt-Rosen, O., Caplen, N. J., Wolfsberg, T. G., Umayam, L., Lee, J. C., Hughes, C. M., Shanmugam, K. S., Bhattecharjee, A., Meyerson, M., and Collins, F. S. (2003) Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc. Natl. Acad. Sci. U.S.A.101, 1892-1897.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 1892-1897
-
-
Scacheri, P.C.1
Rozenblatt-Rosen, O.2
Caplen, N.J.3
Wolfsberg, T.G.4
Umayam, L.5
Lee, J.C.6
Hughes, C.M.7
Shanmugam, K.S.8
Bhattecharjee, A.9
Meyerson, M.10
Collins, F.S.11
-
24
-
-
0037324378
-
Ribonuclease inhibitor as an intracellular sentry
-
DOI 10.1093/nar/gkg163
-
Haigis, M. C., Kurten, E. L., and Raines, R. T. (2003) Ribonuclease inhibitor as an intracellular sentry. Nucleic Acids Res.31, 1024-1032. (Pubitemid 36240441)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.3
, pp. 1024-1032
-
-
Haigis, M.C.1
Kurten, E.L.2
Raines, R.T.3
-
25
-
-
0035478585
-
Macromolecular crowding: Obvious but unappreciated
-
Ellis, R. J. (2001) Macromolecular crowding: Obvious but unappreciated. Trends Biochem. Sci.26, 597-604.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 597-604
-
-
Ellis, R.J.1
-
26
-
-
41049090929
-
Macromolecular crowding and confinement: Biochemical, biophysical, and potential physiological consequences
-
Zhou, H. X., Rivas, G., and Minton, A. P. (2008) Macromolecular crowding and confinement: Biochemical, biophysical, and potential physiological consequences. Annu. Rev. Biophys.37, 375-397.
-
(2008)
Annu. Rev. Biophys.
, vol.37
, pp. 375-397
-
-
Zhou, H.X.1
Rivas, G.2
Minton, A.P.3
-
27
-
-
47749124982
-
Aspects of the cytotoxic action of ribonucleases
-
Arnold, U. (2008) Aspects of the cytotoxic action of ribonucleases. Curr. Pharm. Biotechnol.9, 161-168.
-
(2008)
Curr. Pharm. Biotechnol.
, vol.9
, pp. 161-168
-
-
Arnold, U.1
-
28
-
-
47749138585
-
Intracellular routing of cytotoxic pancreatic-type ribonucleases
-
Benito, A., Vilanova, M., and Ribó, M. (2008) Intracellular routing of cytotoxic pancreatic-type ribonucleases. Curr. Pharm. Biotechnol.9, 169-179.
-
(2008)
Curr. Pharm. Biotechnol.
, vol.9
, pp. 169-179
-
-
Benito, A.1
Vilanova, M.2
Ribó, M.3
-
29
-
-
0025786662
-
Comparison of RNases and toxins upon injection into Xenopus oocytes
-
Saxena, S. K., Rybak, S. M., Winkler, G., Meade, H. M., McGray, P., Youle, R. J., and Ackerman, E. J. (1991) Comparison of RNases and toxins upon injection into Xenopus oocytes. J. Biol. Chem.266, 21208-21214.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 21208-21214
-
-
Saxena, S.K.1
Rybak, S.M.2
Winkler, G.3
Meade, H.M.4
McGray, P.5
Youle, R.J.6
Ackerman, E.J.7
-
30
-
-
0035630691
-
Protein-protein interfaces: Mimics and inhibitors
-
Cochran, A. G. (2001) Protein-protein interfaces: Mimics and inhibitors. Curr. Opin. Chem. Biol.5, 654-659.
-
(2001)
Curr. Opin. Chem. Biol.
, vol.5
, pp. 654-659
-
-
Cochran, A.G.1
-
31
-
-
33646567148
-
Between a rock and a hard place
-
Whitty, A., and Kumaravel, G. (2006) Between a rock and a hard place. Nat. Chem. Biol.2, 112-118.
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 112-118
-
-
Whitty, A.1
Kumaravel, G.2
-
32
-
-
37249004920
-
Reaching for high-hanging fruit in drug discovery at protein-protein interfaces
-
DOI 10.1038/nature06526, PII NATURE06526
-
Wells, J. A., and McClendon, C. L. (2007) Reaching for high-hanging fruit in drug discovery at protein-protein interfaces. Nature450, 1001-1009. (Pubitemid 350273630)
-
(2007)
Nature
, vol.450
, Issue.7172
, pp. 1001-1009
-
-
Wells, J.A.1
McClendon, C.L.2
|