Living with uncertainty in the intensive care unit: Should patients with sepsis be treated with steroids?

JAMA

Volumn 301, Issue 22, 2009, Pages 2388-2390

  Jaeschke, Roman ^a   Angus, Derek C ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CLOPIDOGREL; METHYLPREDNISOLONE; PROTON PUMP INHIBITOR; STEROID; CORTICOSTEROID; GLUCOCORTICOID;

CLINICAL DECISION MAKING; CLINICAL PRACTICE; CORTICOSTEROID THERAPY; DOCTOR PATIENT RELATION; DRUG USE; EDITORIAL; FAMILY COUNSELING; HUMAN; INTENSIVE CARE UNIT; LOW DRUG DOSE; MORTALITY; PATIENT ASSESSMENT; PRACTICE GUIDELINE; PRIORITY JOURNAL; PUBLIC HEALTH PROBLEM; SEPSIS; SEPTIC SHOCK; NOTE;

ADRENAL CORTEX HORMONES; GLUCOCORTICOIDS; HUMANS; INTENSIVE CARE UNITS; SEPSIS;

EID: 67049160491     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2009.829     Document Type: Editorial

References (11)

1. Annane D, Sebille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002;288(7):862-871. (Pubitemid 34898534)
2. Sprung CL, Annane D, Keh D, et al; CORTICUS Study Group. Hydrocortisone therapy for patients with septic shock. N Engl J Med. 2008;358(2):111-124.
3. Dellinger RP, Levy MM, Carlet JM, et al; International Surviving Sepsis Campaign Guidelines Committee. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008;36(1):296-327.
4. Annane D, Bellissant E, Bollaert P-E, et al. Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review. JAMA. 2009; 301(22):2362-2375.
5. Guyatt G, Jaeschke R, Prasad K, Cook DJ. Summarizing the evidence. In: Guyatt G, Rennie D, Meade M, Cook D, eds. Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice. New York, NY: McGraw-Hill; 2008:523-542.
6. Reade MC, Delaney A, Bailey MJ, Angus DC. Bench-to-bedside review: avoiding pitfalls in critical care meta-analysis - funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy. Crit Care. 2008;12(4):220.
7. Guyatt GH, Oxman AD, Vist GE, et al; GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336(7650):924-926. (Pubitemid 351632017)
8. Drazen JM, O'Byrne PM. Risks of long-acting β-agonists in achieving asthma control. N Engl J Med. 2009;360(16):1671-1672.
9. Juurlink DN, Gomes T, Ko DT, et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ. 2009;180 (7):713-718.
10. Jaeschke R, Guyatt GH, Dellinger P, et al. Use of GRADE grid to reach decisions on clinical practice guidelines when consensus is elusive. BMJ. 2008;337:327-330.
11. Sackett DL. The arrogance of preventive medicine. CMAJ. 2002;167(4): 363-364. (Pubitemid 35034634)