Using functional tissue engineering and bioreactors to mechanically stimulate tissue-engineered constructs

Tissue Engineering - Part A

Volumn 15, Issue 4, 2009, Pages 741-749

  Butler, David L ^a   Hunter, Shawn A ^b   Chokalingam, Kumar ^a   Cordray, Michael J ^c   Shearn, Jason ^a   Juncosa Melvin, Natalia ^d   Nirmalanandhan, Sanjit ^e   Jain, Abhishek ^a  

^a University of Cincinnati   (United States)

^b Community Tissue Services ^*  (United States)

^c ZIMMER INC   (United States)

^d Cardioenergetics   (United States)

^e UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; BIOREACTORS; CELL MEMBRANES; FORCE MEASUREMENT; INDUSTRIAL CHEMICALS; PHOTOTRANSISTORS; SILICONES; STIFFNESS; STRAIN; THERMOELECTRICITY; TISSUE;

BIOLOGICAL ACTIVITIES; CELL VIABILITY; CELLULAR ACTIVITIES; CONTROL ENVIRONMENT; DISPLACEMENT PATTERNS; FUNCTIONAL TISSUE; IN-VIVO; MECHANICAL STIMULATION; PATELLAR TENDON; STRAIN PATTERNS; TISSUE-ENGINEERED CONSTRUCTS; WAVE FORMS;

TISSUE ENGINEERING;

ANIMAL EXPERIMENT; ATMOSPHERIC PRESSURE; BIOMECHANICS; BIOREACTOR; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DAILY LIFE ACTIVITY; ELECTROMAGNETIC FIELD; FORCE; HUMIDITY; MECHANICAL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; REACTOR MONITORING; REVIEW; RIGIDITY; TEMPERATURE; TISSUE ENGINEERING; YOUNG MODULUS; ANIMAL; ARTICLE; CELL CULTURE; FEMALE; INSTRUMENTATION; METHODOLOGY;

TISSUE SCAFFOLD;

ANIMALS; BIOREACTORS; CELLS, CULTURED; FEMALE; RABBITS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 67049097981     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2008.0292     Document Type: Review

References (35)

1. Freed, L.E., Langer, R., Martin, I., Pellis, N.R., and Vunjak- Novakovic, G. Tissue engineering of cartilage in space. Proc Natl Acad Sci USA 94, 13885, 1997.
2. Vunjak-Novakovic, G., Obradovic, B., Martin, I., and Freed, L.E. Bioreactor studies of native and tissue engineered cartilage. Biorheology 39, 259, 2002.
3. Banes, A.J., Gilbert, J., Taylor, D., and Monbureau, O. A new vacuum-operated stress-providing instrument that applies static or variable duration cyclic tension or compression to cells in vitro. J Cell Sci 75, 35, 1985.
4. Carvalho, R.S., Yen, E.H., and Suga, D.M. Glycosaminoglycan synthesis in the rat articular disk in response to mechanical stress. Am J Orthod Dentofacial Orthop 107, 401, 1995.
5. Sambajon, V.V., Cillo, J.E., Jr., Gassner, R.J., and Buckley, M.J. The effects of mechanical strain on synovial fibroblasts. J Oral Maxillofac Surg 61, 707, 2003.
6. Upton, M.L., Chen, J., Guilak, F., and Setton, L.A. Differential effects of static and dynamic compression on meniscal cell gene expression. J Orthop Res 21, 963, 2003.
7. Aufderheide, A.C., and Athanasiou, K.A. A direct compression stimulator for articular cartilage and meniscal explants. Ann Biomed Eng 34, 1463, 2006.
8. Frank, E.H., Jin, M., Loening, A.M., Levenston, M.E., and Grodzinsky, A.J. A versatile shear and compression apparatus for mechanical stimulation of tissue culture explants. J Biomech 33, 1523, 2000.
9. Mauck, R.L., Soltz, M.A., Wang, C.C.B., Wong, D.D., Chao, P.H.G., Valhmu, W.B., Hung, C.T., and Ateshian, G.A. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng 122, 252, 2000.
10. Butler, D.L., Goldstein, S.A., and Guilak, F. Functional tissue engineering: the role of biomechanics. J Biomech Eng 122, 570, 2000.
11. Guilak, F., Butler, D.L., Goldstein, S.A., and Mooney, D.J. Functional Tissue Engineering. New York: Springer-Verlag, 2003.
12. Juncosa, N., West, J.R., Galloway, M.T., Boivin, G.P., and Butler, D.L. In vivo forces used to develop design parameters for tissue engineered implants for rabbit patellar tendon repair. J Biomech 36, 483, 2003.
13. Korvick, D., Cummings, J., Grood, E., Holden, J., Feder, S., and Butler, D. The use of an implantable force transducer to measure patellar tendon forces in goats [see comments]. J Biomech 29, 557, 1996.
14. Malaviya, P., Butler, D., Korvick, D., and Proch, F. In vivotendon forces correlate with activity level and remain bounded: evidence in a rabbit flexor tendon model. J Biomech 31, 1043, 1998.
15. West, J.R., Juncosa, N., Galloway, M.T., Boivin, G.P., and Butler, D.L. Characterization of in vivo Achilles tendon forces in rabbits during treadmill locomotion at varying speeds and inclinations. J Biomech 37, 1647, 2004.
16. Ahmed, A.M., and Burke, D.L. In-vitro measurement of static pressure distribution in synovial joints. Part I: Tibial surface of the knee. J Biomech Eng 105, 216, 1983.
17. Brown, T.D., and Shaw, D.T. In vitro contact stress distribution on the femoral condyles. J Orthop Res 2, 190, 1984.
18. Rankin, M., Noyes, F.R., Barber-Westin, S.D., Hushek, S.G., and Seow, A. Human meniscus allografts' in vivo size and motion characteristics: magnetic resonance imaging assessment under weightbearing conditions. Am J Sports Med 34, 98, 2006.
19. Vedi, V., Williams, A., Tennant, S.J., Spouse, E., Hunt, D.M., and Gedroyc, W.M.W. Meniscal movement: an in vivo study using dynamic MRI. J Bone Joint Surg Ser B 81, 37, 1999.
20. Armstrong, C.G., Bahrani, A.S., and Gardner, D.L. In vitromeasurement of articular cartilage deformations in the intact human hip joint under load. J Bone Joint Surg Ser A 61, 744, 1979.
21. Macirowski, T., Tepic, S., and Mann, R.W. Cartilage stresses in the human hip joint. J Biomech Eng 116, 10, 1994.
22. Eckstein, F., Lemberger, B., Gratzke, C., Hudelmaier, M., Glaser, C., Englmeier, K.H., and Reiser, M. In vivo cartilage deformation after different types of actvity and its dependence on physical training status. Ann Rheum Dis 64, 291, 2005.
23. Eckstein, F., Tieschky, M., Faber, S., Englmeier, K.H., and Reiser, M. Functional analysis of articular cartilage defor- mation, recovery, and fluid flow following dynamic exercise in vivo. Anat Embryol 200, 419, 1999.
24. Juncosa-Melvin, N., Boivin, G.P., Galloway, M.T., Gooch, C., West, J.R., and Butler, D.L. Effects of cell-to-collagen ratio in stem cell-seeded constructs for Achilles tendon repair. Tissue Eng 12, 681, 2006.
25. Juncosa-Melvin, N., Boivin, G.P., Galloway, M.T., Gooch, C., West, J.R., Sklenka, A.M., and Butler, D.L. Effects of cellto- collagen ratio in mesenchymal stem cell-seeded implants on tendon repair biomechanics and histology. Tissue Eng 11, 448, 2005.
26. Juncosa-Melvin, N., Boivin, G.P., Gooch, C., Galloway, M.T., West, J.R., Dunn, M.G., and Butler, D.L. The effect of autologous mesenchymal stem cells on the biomechanics and histology of gel-collagen sponge constructs used for rabbit patellar tendon repair. Tissue Eng 12, 369, 2006.
27. Juncosa-Melvin, N., Matlin, K.S., Holdcraft, R.W., Nirmalanandhan, V.S., and Butler, D.L. Mechanical stimulation increases collagen type I and collagen type III gene expression of stem cell-collagen sponge constructs for patellar tendon repair. Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007, 2007, pp. 981- 982.
28. Juncosa-Melvin, N., Shearn, J.T., Boivin, G.P., Gooch, C., Galloway, M.T., West, J.R., Nirmalanandhan, V.S., Bradica, G., and Butler, D.L. Effects of mechanical stimulation on the biomechanics and histology of stem cell-collagen sponge constructs for rabbit patellar tendon repair. Tissue Eng 12, 2291, 2006.
29. Nirmalanandhan, V.S., Dressler, M.R., Shearn, J.T., Juncosa- Melvin, N., Rao, M., Gooch, C., Bradica, G., and Butler, D.L. Mechanical stimulation of tissue engineered tendon constructs: effect of scaffold materials. J Biomech Eng 129, 919, 2007.
30. Shearn, J.T., Juncosa-Melvin, N., Boivin, G.P., Galloway, M.T., Goodwin, W., Gooch, C., Dunn, M.G., and Butler, D.L. Mechanical stimulation of tendon tissue engineered constructs: effects on construct stiffness, repair biomechanics, and their correlation. J Biomech Eng 129, 848, 2007.
31. Nirmalanandhan, V.S., Shearn, J.T., Juncosa-Melvin, N., Rao, M., Gooch, C., Bradica, G., and Butler, D.L. Improving linear stiffness of the cell-seeded collagen sponge constructs by varying the components of the mechanical stimulus. Tissue Eng 14, 1883, 2008.
32. Thirion, S., and Berenbaum, F. Culture and phenotyping of chondrocytes in primary culture.Methods MolMed 100, 1, 2004.
33. Butler, D.L., Juncosa-Melvin, N., Boivin, G.P., Galloway, M.T., Shearn, J.T., Gooch, C., and Awad, H. Functional tissue engineering for tendon repair: a multidisciplinary strategy using mesenchymal stem cells, bioscaffolds, and mechanical stimulation. J Orthop Res 26, 1, 2008.
34. Lysaght, M.J., Nguy, N.A.P., and Sullivan, K. An economic survey of the emerging tissue engineering industry. Tissue Eng 4, 231, 1998.
35. Altman, G.H., Lu, H.H., Horan, R.L., Calabro, T., Ryder, D., Kaplan, D.L., Stark, P., Martin, I., Richmond, J.C., and Vunjak-Novakovic, G. Advanced bioreactor with controlled application of multi-dimensional strain for tissue engineering. J Biomech Eng 124, 742, 2002.