B-type natriuretic peptide 8-32, which is produced from mature BNP 1-32 by the metalloprotease meprin A, has reduced bioactivity

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 296, Issue 6, 2009, Pages

  Boerrigter, Guido ^a   Costello Boerrigter, Lisa C ^a   Harty, Gail J ^a   Huntley, Brenda K ^a   Cataliotti, Alessandro ^a   Lapp, Harald ^b   Burnett Jr , John C ^a  

^a MAYO CLINIC   (United States)

^b HELIOS KLINIKUM ERFURT   (Germany)

Author keywords

Cardiorenal regulation; Hormone; Natriuretic peptides; Peptidase

Indexed keywords

AMINO ACID; BRAIN NATRIURETIC PEPTIDE [1-32]; BRAIN NATRIURETIC PEPTIDE [8-32]; DIURETIC AGENT; MEPRIN; POTASSIUM; SODIUM; UNCLASSIFIED DRUG; VASODILATOR AGENT;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; AORTA; ARTICLE; CONTROLLED STUDY; DIURETIC ACTIVITY; DRUG CLEARANCE; DRUG SYNTHESIS; ENDOTHELIUM CELL; EXPERIMENTAL DOG; GLOMERULUS FILTRATION RATE; HEART OUTPUT; HEART RATE; HEART RIGHT ATRIUM PRESSURE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; KIDNEY BLOOD FLOW; MALE; MEAN ARTERIAL PRESSURE; MICTURITION; NONHUMAN; POTASSIUM URINE LEVEL; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION PRESSURE; SODIUM URINE LEVEL; VASODILATATION;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL MARKERS; CARDIOVASCULAR SYSTEM; CELLS, CULTURED; CYCLIC GMP; DIURESIS; DOGS; ENDOTHELIAL CELLS; HEMODYNAMICS; HUMANS; INFUSIONS, INTRAVENOUS; KIDNEY; MALE; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; NATRIURESIS; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS;

EID: 67049097207     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00059.2009     Document Type: Article

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