Stage i seminoma: What should a practicing uro-oncologist do in 2009?

International Journal of Urology

Volumn 16, Issue 6, 2009, Pages 544-551

  Skliarenko, Julia ^a   Vesprini, Danny ^a   Warde, Padraig ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b Department of Radiation Oncology ^*  (Canada)

Author keywords

Chemotherapy; Radiation; Seminoma; Stage I; Surveillance

Indexed keywords

CARBOPLATIN; FLUORODEOXYGLUCOSE;

ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; CANCER EPIDEMIOLOGY; CANCER RADIOTHERAPY; CANCER RELAPSE; CANCER STAGING; CARDIOVASCULAR RISK; DIAGNOSTIC IMAGING; GERM CELL TUMOR; HUMAN; METASTASIS; ORCHIECTOMY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; REVIEW; SEMINOMA; SOLID TUMOR;

CHEMOTHERAPY, ADJUVANT; HUMANS; MALE; NEOPLASM STAGING; RADIOTHERAPY, ADJUVANT; SEMINOMA; TESTICULAR NEOPLASMS;

EID: 66949155027     PISSN: 09198172     EISSN: 14422042     Source Type: Journal    
DOI: 10.1111/j.1442-2042.2009.02296.x     Document Type: Review

References (58)

1. Jemal A, Siegel R, Ward E et al. Cancer statistics, 2008. CA Cancer J. Clin. 2008 58 : 71 96.
2. Bray F, Ferlay J, Devesa SS, McGlynn KA, Moller H. Interpreting the international trends in testicular seminoma and nonseminoma incidence. Nat. Clin. Pract. Urol. 2006 3 : 532 43.
3. McGlynn KA, Devesa SS, Sigurdson AJ, Brown LM, Tsao L, Tarone RE. Trends in the incidence of testicular germ cell tumors in the United States. Cancer 2003 97 : 63 70. (Pubitemid 36033864)
4. Sokoloff MH, Joyce GF, Wise M. Testis cancer. J. Urol. 2007 177 : 2030 41.
5. Warde P, Sturgeon J, Gospodarowicz M. Testicular cancer. In : Gunderson L, Tepper J (eds). Clinical Radiation Oncology. Churchill Livingstone, Philadelphia, PA, 2000 844 62.
6. Zagars GK, Ballo MT, Lee AK, Strom SS. Mortality after cure of testicular seminoma. J. Clin. Oncol. 2004 22 : 640 7.
7. Travis LB, Fossa SD, Schonfeld SJ et al. Second cancers among 40 576 testicular cancer patients: focus on long-term survivors. J. Natl. Cancer Inst. 2005 97 : 1354 65.
8. Robinson D, Moller H, Horwich A. Mortality and incidence of second cancers following treatment for testicular cancer. Br. J. Cancer 2007 96 : 529 33.
9. Huddart RA, Norman A, Shahidi M et al. Cardiovascular disease as a long-term complication of treatment for testicular cancer. J. Clin. Oncol. 2003 21 : 1513 23.
10. Daugaard G, Petersen PM, Rorth M. Surveillance in stage I testicular cancer. APMIS 2003 111 : 76 83.
11. Horwich A, Alsanjari N, A'Hern R, Nicholls J, Dearnaley DP, Fisher C. Surveillance following orchidectomy for stage I testicular seminoma. Br. J. Cancer 1992 65 : 775 8.
12. von der Maase H, Specht L, Jacobsen GK et al. Surveillance following orchidectomy for stage I seminoma of the testis.[see comment Eur. J. Cancer 1993 29A : 1931 4.
13. Aparicio J, Garcia del Muro X, Maroto P et al. Multicenter study evaluating a dual policy of postorchiectomy surveillance and selective adjuvant single-agent carboplatin for patients with clinical stage I seminoma. Ann. Oncol. 2003 14 : 867 72.
14. Aparicio J, Germa JR, Del Muro XG et al. Management for patients with clinical stage I seminoma: the second spanish germ cell cancer cooperative group study. J. Clin. Oncol. 2005 23 : 8717 23.
15. Powles T, Robinson D, Shamash J, Moller H, Tranter N, Oliver T. The long-term risks of adjuvant carboplatin treatment for stage I seminoma of the testis. Ann. Oncol. 2008 19 : 443 7.
16. Horwich A. Stage I seminoma and carboplatin risks. Ann. Oncol. 2008 19 : 407 8.
17. Mezvrishvili Z, Managadze L. Retroperitoneal lymph node dissection for high-risk stage I and stage IIA seminoma. Int. Urol. Nephrol. 2006 38 : 615 19.
18. Satoh M, Ito A, Kaiho Y et al. Intraoperative, radio-guided sentinel lymph node mapping in laparoscopic lymph node dissection for stage I testicular carcinoma. Cancer 2005 103 : 2067 72.
19. Sohaib SA, Koh DM, Husband JE. The role of imaging in the diagnosis, staging, and management of testicular cancer. AJR Am. J. Roentgenol. 2008 191 : 387 95.
20. Hilton S, Herr HW, Teitcher JB, Begg CB, Castellino RA. CT detection of retroperitoneal lymph node metastases in patients with clinical stage I testicular nonseminomatous germ cell cancer: assessment of size and distribution criteria. Am. J. Roentgenol. 1997 169 : 521 5.
21. Harisinghani MG, Saksena M, Ross RW et al. A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation. Urology 2005 66 : 1066 71.
22. Germa-Lluch JR, Garcia del Muro X, Maroto P et al. Clinical pattern and therapeutic results achieved in 1490 patients with germ-cell tumours of the testis: the experience of the Spanish Germ-Cell Cancer Group (GG). Eur. Urol. 2002 42 : 553 62.
23. Warde PR, Chung P, Sturgeon J et al. Should surveillance be considered the standard of care in stage I seminoma? J. Clin. Oncol. (Meeting Abstracts) 2005 23 : 4520.
24. Ramakrishnan S, Champion AE, Dorreen MS, Fox M. Stage I seminoma of the testis: is post-orchidectomy surveillance a safe alternative to routine postoperative radiotherapy? Clin. Oncol. (R Coll Radiol) 1992 4 : 284 6.
25. Chung P, Parker C, Panzarella T et al. Surveillance in stage I testicular seminoma - risk of late relapse. Can. J. Urol. 2002 9 : 1637 40.
26. Warde P, Gospodarowicz MK, Banerjee D et al. Prognostic factors for relapse in stage I testicular seminoma treated with surveillance. J. Urol. 1997 157 : 1705 1709.
27. Warde P, Specht L, Horwich A et al. Prognostic factors for relapse in stage I seminoma managed by surveillance: a pooled analysis. J. Clin. Oncol. 2002 20 : 4448 52.
28. Martin JM, Panzarella T, Zwahlen DR, Chung P, Warde P. Evidence-based guidelines for following stage 1 seminoma. Cancer 2007 109 : 2248 56.
29. Krege S, Beyer J, Souchon R et al. European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I. Eur. Urol. 2008 53 : 478 96.
30. Krege S, Beyer J, Souchon R et al. European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II. Eur. Urol. 2008 53 : 497 513.
31. Bayens YC, Helle PA, Van Putten WL, Mali SP. Orchidectomy followed by radiotherapy in 176 stage I and II testicular seminoma patients: benefits of a 10-year follow-up study. Radiother. Oncol. 1992 25 : 97 102.
32. Coleman JM, Coleman RE, Turner AR, Radstone CR, Champion AE. The management and clinical course of testicular seminoma: 15 years' experience at a single institution. Clin. Oncol. (R Coll Radiol) 1998 10 : 237 41.
33. Fossa SD, Horwich A, Russell JM et al. Optimal planning target volume for stage I testicular seminoma: a Medical Research Council randomized trial. Medical Research Council Testicular Tumor Working Group [see comment J. Clin. Oncol. 1999 17 : 1146.
34. Jones WG, Fossa SD, Mead GM et al. Randomized trial of 30 versus 20 Gy in the adjuvant treatment of stage I testicular seminoma: a report on Medical Research Council Trial TE18, European Organisation for the Research and Treatment of Cancer Trial 30942 (ISRCTN18525328). J. Clin. Oncol. 2005 23 : 1200 8.
35. Santoni R, Barbera F, Bertoni F et al. Stage I seminoma of the testis: a bi-institutional retrospective analysis of patients treated with radiation therapy only. BJU Int. 2003 92 : 47 52. (Pubitemid 36843027)
36. Raina V, Singh SP, Kamble N et al. Brain metastasis as the site of relapse in germ cell tumor of testis. Cancer 1993 72 : 2182 5.
37. Rathmell AJ, Mapstone NP, Jones WG. Testicular seminoma metastasizing to palatine tonsil. Clin. Oncol. (R Coll Radiol) 1993 5 : 185 6.
38. Warde P, Gospodarowicz MK, Panzarella T et al. Stage I testicular seminoma: results of adjuvant irradiation and surveillance. J. Clin. Oncol. 1995 13 : 2255 62.
39. Logue JP, Harris MA, Livsey JE, Swindell R, Mobarek N, Read G. Short course para-aortic radiation for stage I seminoma of the testis. Int. J. Radiat. Oncol. Biol. Phys. 2003 57 : 1304 9.
40. Classen J, Schmidberger H, Meisner C et al. Para-aortic irradiation for stage I testicular seminoma: results of a prospective study in 675 patients. A trial of the German testicular cancer study group (GTCSG). Br. J. Cancer 2004 90 : 2305 11.
41. Melchior D, Hammer P, Fimmers R, Schuller H, Albers P. Long term results and morbidity of paraaortic compared with paraaortic and iliac adjuvant radiation in clinical stage I seminoma. Anticancer Res. 2001 21 : 2989 93.
42. Thomas GM. Is 'optimal' radiation for stage I seminoma yet defined? J. Clin. Oncol. 1999 17 : 3004 5.
43. Donohue J, Thornhill J, Foster R, Rowland R, Bihrle R. Retroperitoneal lymphadenectomy for clinical stage A testis cancer (1965-1989): modifications of technique and impact on ejaculation. J. Urol. 1993 149 : 237 43.
44. Schmidberger H, Bamberg M, Meisner C et al. Radiotherapy in stage IIA and IIB testicular seminoma with reduced portals: a prospective multicenter study. Int. J. Radiat. Oncol. Biol. Phys. 1997 39 : 321 6.
45. Gurkaynak M, Akyol F, Zorlu F, Akyurek S, Yildiz F, Atahan IL. Stage I testicular seminoma: para-aortic and iliac irradiation with reduced dose after orchiectomy. Urol. Int. 2003 71 : 385 8.
46. Fossa SD, Abyholm T, Normann N, Jetne V. Post-treatment fertility in patients with testicular cancer. III. Influence of radiotherapy in seminoma patients. Br. J. Urol. 1986 58 : 315 19.
47. Moller H, Friis S, Kjaer SK. Survival of Danish cancer patients 1943-1987. Male genital organs. APMIS Suppl. 1993 33 : 122 36.
48. van den Belt-Dusebout AW, de Wit R, Gietema JA et al. Treatment-specific risks of second malignancies and cardiovascular disease in 5-year survivors of testicular cancer. J. Clin. Oncol. 2007 25 : 4370 8.
49. Horwich A. Radiotherapy in stage I seminoma of the testis. J. Clin. Oncol. 2004 22 : 585 8.
50. Dieckmann KP, Bruggeboes B, Pichlmeier U, Kuster J, Mullerleile U, Bartels H. Adjuvant treatment of clinical stage I seminoma: is a single course of carboplatin sufficient? Urology 2000 55 : 102 6.
51. Oliver RT, Edmonds PM, Ong JY et al. Pilot studies of 2 and 1 course carboplatin as adjuvant for stage I seminoma: should it be tested in a randomized trial against radiotherapy? Int. J. Radiat. Oncol. Biol. Phys. 1994 29 : 3 8. (Pubitemid 24138858)
52. Oliver R, Boubilkova L, Ong J. Fifteen-year follow-up of the Anglian Germ Cell Cancer group adjuvant studies of carboplatin as an alternative to radiation or surveillance for stage 1 seminoma (Abstract). Proc. ASCO 2001 19 : 780.
53. Oliver RT, Mason MD, Mead GM et al. Radiotherapy versus single-dose carboplatin in adjuvant treatment of stage I seminoma: a randomised trial. Lancet 2005 366 : 293 300. (Pubitemid 41019418)
54. Krege S, Kalund G, Otto T, Goepel M, Rubben H. Phase II study: adjuvant single-agent carboplatin therapy for clinical stage I seminoma. Eur. Urol. 1997 31 : 405 7.
55. Argirovic D. Germ cell testicular tumors in clinical stage A and normal values of serum tumor markers post-orchiectomy: the experience in the management of 300 consecutive patients. J. BUON 2005 10 : 195 200. (Pubitemid 41320559)
56. Steiner H, Holtl L, Wirtenberger W, Berger AP, Bartsch G, Hobisch A. Long-term experience with carboplatin monotherapy for clinical stage I seminoma: a retrospective single-center study. Urology 2002 60 : 324 8.
57. Alomary I, Samant R, Genest P, Eapen L, Gallant V. The preferred treatment for stage I seminoma: a survey of Canadian radiation oncologists. Clin. Oncol. (R Coll Radiol) 2006 18 : 696 9.
58. Choo R, Sandler H, Warde P, Hruby G, DeBoer G. Survey of radiation oncologists: practice patterns of the management of stage I seminoma of testis in Canada and a selected group in the United States. Can. J. Urol. 2002 9 : 1479 85.