The effect of subclinical hypothyroidism on platelet parameters

Hematology

Volumn 14, Issue 2, 2009, Pages 115-117

  Erikci, Alev Akyol ^a   Karagoz, Bulent ^a   Ozturk, Ahmet ^a   Caglayan, Sinan ^a   Ozisik, Gokhan ^a   Kaygusuz, Isik ^b   Ozata, Metin ^a  

^a GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

^b MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Mean platelet volume; Platelets; Subclinical hypothyroidism

Indexed keywords

ADULT; ARTICLE; ATHEROSCLEROSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; DISEASE PREDISPOSITION; EUTHYROIDISM; FEMALE; HEMATOLOGICAL PARAMETERS; HUMAN; HYPOTHYROIDISM; INTERMETHOD COMPARISON; MALE; PRIORITY JOURNAL; PROGNOSIS; THROMBOCYTE COUNT; THROMBOCYTE DISTRIBUTION WIDTH; THROMBOCYTE VOLUME;

ADULT; BLOOD PLATELETS; CASE-CONTROL STUDIES; FEMALE; HUMANS; HYPOTHYROIDISM; MALE; MIDDLE AGED; PLATELET ACTIVATION; PLATELET COUNT; THYROID HORMONES;

EID: 66949138643     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453309X385124     Document Type: Article

References (21)

1. Cooper DS, Halpern R, Wood LC, Levin AA, Ridgway EC. L-Thyroxine therapy in subclinical hypothyroidism. A double-blind, placebo-controlled trial. Ann Intern Med 1984; 101: 18-24.
2. Cappola AR, Ladenson PW. Hypothyroidism and atherosclerosis. J Clin Endocrinol Metab 2003; 88: 2438-2444.
3. Benzaquen LR, Yu H, Rifai N. High sensitivity C-reactive protein: An emerging role in cardiovascular risk assessment. Crit Rev Clin Lab Sci 2002; 39: 459-497.
4. van der Loo B, Martin JF. A role for changes in platelet production in the cause of acute coronary syndromes. Arterioscler Thromb Vasc Biol 1999; 19: 672-679.
5. Danese MD, Powe NR, Sawin CT, Ladenson PW. Screening for mild thyroid failure at the periodic health examination: A decision and cost-effectiveness analysis. JAMA 1996; 276: 285-292
6. Hak AE, Pols HAP, Visser TJ, Drexhage HA, Hofman A, Witteman JC. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: The Rotterdam Study. Ann Intern Med 2000; 132: 270-278.
7. Bath PM, Butterworth RJ. Platelet size: Measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 1996; 7: 157-161.
8. Greisenegger S, Endler G, Hsieh K, Tentschert S, Mannhalter C, Lalouschek W. Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events? Stroke 2004; 35: 1688-1691.
9. Endler G, Klimesch A, Sunder-Plassmann H et al. Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. Br J Haematol 2002; 117: 399-404.
10. Kiliçli-Camur N, Demirtunç R, Konuralp C, Eskiser A, Başaran Y. Could mean platelet volume be a predictive marker for acute myocardial infarction? Med Sci Monit 2005; 11: 387-392.
11. Coban E, Ozdogan M, Yazicioglu G, Akcit F. The mean platelet volume in patients with obesity. Int J Clin Pract 2005; 59: 981-982.
12. Coban E, Bostan F, Ozdogan M. The mean platelet volume in subjects with impaired fasting glucose. Platelets 2006; 17: 67-69.
13. Saigo K, Yasunaga M, Ryo R. Mean platelet volume in diabetics. Rinsha Byar 1992; 40: 215-217.
14. Sharpe PC, Trinick T. Mean platelet volume in diabetes mellitus. Q J Med 1993; 86 (11): 739-742.
15. Hekimsoy Z, Payzin B, Ornek T, Kandogan G. Mean platelet volume in type 2 diabetic patients. J Diabetes Complications 2004; 18: 173-176.
16. Jones RL, Paradise C, Peterson CM. Platelet survival in patients with diabetes mellitus. Diabetes 1981; 30: 486-489.
17. Panzer S, Haubenstock A, Minar E. Platelets in hyperthyroidism: Studies on platelet counts, mean platelet volume, 111-indium-labeled platelet kinetics, and platelet-associated immunoglobulins G and M. J Clin Endocrinol Metab 1990; 70: 491-496.
18. Marongiu F, Conti M, Murtas ML, Mameli G, Sorano GG, Martino E. What causes the increase in platelet mean volume in thyroid pathological conditions? Thromb Haemost 1990; 63: 323- 324.
19. van Doormaal JJ, van der Meer J, Oosten HR, Halie MR, Doorenbos H. Hypothyroidism leads to more small-sized platelets in circulation. Thromb Haemost 1987; 58: 964-965.
20. Ford HC, Carter JM. Moderate, chronic hypothyroidism does not lead to more small-sized platelets in the circulation. Thromb Haemost 1988; 60: 524.
21. Coban E, Yazicioglu G, Ozdogan M. Platelet activation in subjects with subclinical hypothyroidism. Med Sci Monit 2007; 13: 211-214.