The influence of intensive insulin therapy on hemodynamics in patients with septic shock

Chinese Critical Care Medicine

Volumn 21, Issue 5, 2009, Pages 290-292

  Dong, Shi Min ^a   Qin, Yan Jun ^a   Gao, Yu Fang ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Glucose; Hemodynamics; Insulin; Myocardial depression; Sepsis

Indexed keywords

GLUCOSE; INSULIN; LACTIC ACID;

APACHE; ARTICLE; BLOOD OXYGENATION; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEART FUNCTION; HEART INDEX; HEART STROKE VOLUME; HEMODYNAMICS; HUMAN; HYPOGLYCEMIA; INSULIN INFUSION; LACTATE BLOOD LEVEL; MEAN ARTERIAL PRESSURE; MYOCARDIAL DISEASE; PULMONARY ARTERY CATHETER; SEPTIC SHOCK; TREATMENT OUTCOME;

ADULT; FEMALE; HEART; HEMODYNAMICS; HUMANS; INSULIN; MALE; MIDDLE AGED; SHOCK, SEPTIC;

EID: 66949136296     PISSN: 10030603     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.1003-0603.2009.05.012     Document Type: Article

References (12)

1. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients. N Engl J Med, 2001,345(19):1359-1367. (Pubitemid 34940724)
2. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest, 1992,101(6):1644-1655.
3. Fernandes CJ Jr, Akamine N, Knobel E. Myocardial depression in sepsis. Shock, 2008,30(Suppl 1):14-17.
4. Levy RJ, Piel DA, Acton PD, et al. Evidence of myocardial hibernation in the septic heart. Crit Care Med, 2005,33(12):2752-2756. (Pubitemid 41816407)
5. Das UN. Insulin: an endogenous cardioprotector. Curr Opin Crit Care, 2003,9(5):375-383.
6. Hamdulay SS, Al-Khafaji A, Montgomery H. Glucose-insulin and potassium infusions in septic shock. Chest, 2006,129(3):800-804.
7. Gao F, Gao E, Yue TL, et al. Nitric oxide mediates the anti-apoptotic effect of insulin in myocardial ischemia-reperfusion, the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation, 2002,105(12):1497-1502. (Pubitemid 34263284)
8. Hagiwara S, Iwasaka H, Hasegawa A, et al. Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model. Crit Care Med, 2008,36(8):2407-2413.
9. Ali NA, O'Brien JM Jr, Dungan K, et al. Glucose variability and mortality in patients with sepsis. Crit Care Med, 2008,36(8):2316-2321.