Ultraviolet A irradiation of the eye activates a nitric oxide-dependent hypothalamo-pituitary pro-opiomelanocortin pathway and modulates the functions of Langerhans cells

Journal of Dermatology

Volumn 36, Issue 6, 2009, Pages 335-345

  Hiramoto, Keiichi ^a,b  

^a KITASATO INSTITUTE   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Langerhans cells; Nitric oxide; Pro opiomelanocortin; Signaling; Ultraviolet A

Indexed keywords

ALPHA INTERMEDIN; CORTICOTROPIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROOPIOMELANOCORTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTACT ALLERGY; CONTROLLED STUDY; DENERVATION; DNA FRAGMENTATION; DOWN REGULATION; EPIDERMIS; GANGLIONECTOMY; HORMONE BLOOD LEVEL; HYPOPHYSECTOMY; HYPOTHALAMUS HYPOPHYSIS SYSTEM; LANGERHANS CELL; MALE; MOUSE; NONHUMAN; OPTIC NERVE; RADIATION DOSE; ULTRAVIOLET A RADIATION;

ADRENOCORTICOTROPIC HORMONE; ALPHA-MSH; ANIMALS; DERMATITIS, CONTACT; EPIDERMIS; EYE; FLUORESCEIN-5-ISOTHIOCYANATE; GANGLIONECTOMY; HYPOPHYSECTOMY; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNOSUPPRESSION; IN SITU NICK-END LABELING; LANGERHANS CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OPTIC NERVE; PRO-OPIOMELANOCORTIN; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS;

EID: 66949132942     PISSN: 03852407     EISSN: 13468138     Source Type: Journal    
DOI: 10.1111/j.1346-8138.2009.00649.x     Document Type: Article

References (48)

1. Noonan FP, Kripke ML, Pedersen GM, Greene MI. Suppression of content hypersensitivity by UV radiation is associated with defective antigen presentation. Immunology 1981 46 : 527 533. (Pubitemid 11095784)
2. Ullich SE, Azizi E, Kripke ML. Suppression of the induction of delayed hypersensitivity reactions in mice by a single exposure to UV radiation. Photochem Photobiol 1986 43 : 633 638.
3. Rattis FM, Peguet-Navarro J, Courtellemont P, Redziniak G, Shinitt D. In vitro effects of ultraviolet B irradiation on human Langerhans cell antigen-presenting function. Cell Immunol 1995 164 : 65 72.
4. Tang A, Udey MC. Inhibition of epidermal Langerhans cell function by low dose ultraviolet B radiation. J Immunol 1991 146 : 3347 3355.
5. Yoshikawa J, Rae V, Bruins-lot W, Berg J-Wvd, Taylor JR, Streilein JW. Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans. J Invest Dermatol 1990 95 : 530 536.
6. Toews GB, Bergstresser PR, Streilein JN. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J Immunol 1980 124 : 445 449.
7. + cells of the helper 2 subset. J Immunol 1990 145 : 2087 2091. (Pubitemid 20343369)
8. Simon JC, Tigelaar RE, Bergstresser PR, Edelbaum D, Cruz PD. Ultraviolet B radiation converts Langerhans cells from immunogenic to tolerogenic antigen-presenting cells. J immunol 1991 146 : 485 491.
9. Enk AH, Angeloni VL, Udey MC, Katz SI. Inhibition of Langerhans cell antigen-presenting function by IL-10. J Jmmunol 1993 151 : 2390 2398.
10. Rivas JM, Ullrich SE. Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10. J Immunol 1992 149 : 3865 3871. (Pubitemid 23068866)
11. Roza L, Baan R, van der Leun J, Kligman L, Young A. UVA Hazards in skin associated with the use of tanning equipment. J photochem Photobiol 1989 3 : 281 289.
12. Peak J, Peak M, Sikorski R, Jones C. Induction of DNA-protein crosslinks in human cells by ultraviolet and visible radiation: action spectrum. Photochem Photobiol 1985 41 : 295 302.
13. Black H. Potential involvement of free radiation reactions in ultraviolet light-mediated cutaneous damage. Photochem Photobiol 1987 46 : 213 221.
14. Shindo Y, Witt E, Han D et al. Recovery of antioxidants and reduction in lipid hydroperoxides in murine epidermis and dermis after acute oltraviolet radiation exposure. Photodermatol Photoimmunol Photomed 1994 10 : 183 191. (Pubitemid 24357433)
15. Tyrrell R, Keyse S. The interaction of UVA radiation with cultured cells. Photochem Photobiol B Biol 1990 4 : 49 361.
16. + dendritic epidermal cells in murine epidermis during the evolution of ultraviolet radiation-induced skin cancers. Cancer Res 1989 49 : 4591 1596.
17. Grabbe J, Welker P, Humke S et al. High-dose ultraviolet A1 (UVA1), but not UVA/UVB therapy, decreases Ig-E binding cells in lesional slin of patients with atopic eczema. J Invest Dermatol 1996 107 : 419 422.
18. Lavker R, Gerberick G, Veres D, Irwin C, Kaidbey K. Cumulative effect from repeated exposures to suberythemal doses of UVB and UVA in human skin. J Am Acad Dermatol 1995 32 : 53 62.
19. Clement-Lacraix P, Michel L, Moysan A, Morliere P, Dubertret L. UVA-induced immune suppression in human skin: protective effect of vitamin E in human epidermal cells in vitro. Br J Dermatol 1996 134 : 77 84. (Pubitemid 26029666)
20. Bestak R, Halliday G. Chronic low-dose UVA irradiation induces local suppression of contact hypersensitivity, Langerhans cell depletion and suppressor cell activation in C3H/Hej mice. Photochem Photobiol 1996 64 : 969 974. (Pubitemid 27058973)
21. Bruch-Gerharz D, Ruzicka T, Kolb-Bachofen V. Nitric oxide in human skin-current status and future prospects. J Invest Dermatol 1998 110 : 1 7. (Pubitemid 28086054)
22. Romerograillet C, Aberdam E, Clement M, Ortonne JP, Ballotti R. Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis. J Clin Invest 1997 99 : 635 642. (Pubitemid 27097664)
23. Warren JB, Loi RK, Coulan ML. Involvement of nitric oxide synthase in the delayed vasodilator response to ultraviolet light irradiation of rat skin in vivo. Br J Pharmacol 1993 109 : 802 806. (Pubitemid 23181064)
24. Gillardon F, Moll I, Michel S, Benrath J, Weihe E, Zimmermann M. Calcitonin gene-related peptide and nitric oxide are involved in ultraviolet radiation-induced immunosuppression. Eur J pharmacol-Environ Toxical Pharmacol 1995 293 : 395 400. (Pubitemid 3006663)
25. Hiramoto K, Mashita Y, Katada T, Konishi H, Sugiura M, Hayakawa R. Immunosuppression by ultraviolet B rays via eyes in mice. Arch Dermatol Res 1997 289 : 709 711. (Pubitemid 28014203)
26. Jacob MH, Berg DK. Effects of preganglionic denervation and postganglionic axotomy on acetylcholine receptors in the chick ciliary ganglion. J Cell Biol 1987 105 : 1847 1854. (Pubitemid 18023380)
27. Meyer RL, Miotke JA, Benowitz LI. Injury induced expression of growth-associated protein-43 in adult mouse retinal ganglion cells in vitro. Neuroscience 1994 63 : 591 602. (Pubitemid 24357380)
28. Torii H, Tamaki K, Granstein RD. The effect of neuropeptides/hormones on Langerhans cells. J Dermatol Sci 1999 20 : 21 28. (Pubitemid 29197367)
29. Grabbe S, Steinbrink K, Steinert M, Luger TA, Schwarz T. Removal of the Majority of Epidermal Langerhans cells by topical or systemic steroid application enhances the effector phase of murine contact hypersensitivity. J Immunol 1995 155 : 4207 4217.
30. Moncada S, Palmer RM, Higgs EA. Nitric oxide physiology, pathophysiology and pharmacology. Pharmacol Rev 1994 43 : 109 142.
31. Wei XQ, Charles IG, Smith A et al. Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 1994 375 : 408 411.
32. MacMicking JD, Nathan C, Hom G et al. Altered response to bacterial infection and endotoxin shock in mice lacking inducible nitric oxide synthase. Cell 1994 81 : 641 650.
33. Iturriza FC, Eberle AN. Secretion of melanocyte-stimulating hormone and adrenocorticotropin from transplanted pituitary pars intermedia in stressed and nonstressed rats. Neuroendocrinology 1989 49 : 610 616. (Pubitemid 19154613)
34. Surendran N, Ugwu SO, Sterling EJ, Blanchard J. High- performance liquid chromatographic assay for melanoton-1 ([Nle4-Dphe7]α-melanocyte- stimulating hormone) in biological matrices. J Chromatogr B 1995 670 : 235 242.
35. Zuclich JA. Ultraviolet-induced photochemical damage in ocular tissues. Health Phys 1989 56 : 671 82.
36. Lipton JM. Neuroimmune networks. In : Goetzl EJ, Spector NH, eds. Physiology and Diseases. NewYork : Alan R. Liss, 1989 : 243 250.
37. Lipton JM, Catania A. Anti-inflammatory actions of the neuroimmunomodulator αMSH. Immunol Today 1997 18 : 140 145. (Pubitemid 27087303)
38. Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 1995 332 : 1351 1362.
39. Elenkov TJ, Chrousos GP. Stress hormones Th1/Th2 patterns, pro/anti-inflammatory cytokines and susceptibility to disease. Trends Endocrinol Metab 1999 10 : 359 368. (Pubitemid 29496010)
40. Bohm M, Wolff I, Scholzen TE et al. α-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage. J Biol Chem 2005 280 : 5795 5802. (Pubitemid 40280060)
41. Reichardt HM, Umland T, Bauer A, Kretz O, Schutz G. Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock. Mol Cell Biol 2000 20 : 9009 9017. (Pubitemid 32245930)
42. Elftman MD, Norbury CC, Bonneau RH, Truckenmiller ME. Corticosterone impairs dendritic cell maturation and function. Immunology 2007 122 : 279 290. (Pubitemid 47389956)
43. Furio L, Berthier-Vergnes O, Ducarre B, Schmitt D, Peguet-Navarro J. UVA radiation impairs phenotypic and functional maturation of human dermal dendritic cells. J Invest Dermatol 2005 125 : 1032 1038.
44. Pena-Cruz V, Ito S, Dascher CC, Brenner MB, Sugita M. Epidermal Langerhans cells efficiently mediate CD1a-dependent prementation of microbial lipid antigens to T cells. J Invest Dermatol 2003 121 : 517 521. (Pubitemid 37072263)
45. Yuen KS, Nearn MR, Halliday GM. Nitric oxide-mediated depletion of Langerhans cells from the epidermis may be involved in UVA radiation-induced immunosuppression. Nitric Oxide 2002 6 : 313 318. (Pubitemid 34852375)
46. Kuchel JM, Barnetson RSC, Halliday GM. Nitric oxide appears to be a mediator of solar-simulated ultraviolet radiation-induced immunosuppression in humans. J Invest Dermatol 2003 121 : 587 593. (Pubitemid 37072272)
47. Clement-Lacroix P, Michel L, Moysan A, Morliere P, Dubertret L. UVA-induced immunosuppression in human skin: Protective effect of vitamin E in human epidermal cells in vitro. Br J Dermatol 1996 134 : 77 84. (Pubitemid 26029666)
48. Luger TA, Scholzen T, Brzoska T, Becher E, Slominski A, Paus R. Cutaneous Immunomodulation and coordination of skin stress responses by α-melanocyte-stimulating hormone. Ann NY Acad Sci 1998 840 : 381 394.