Synthesis of new 2-thio-[1,2,4]triazolo[1,5-c]quinazoline derivatives and its antimicrobial activity

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 6, 2009, Pages 580-585

  Antipenko, Lyudmila ^a   Karpenko, Alexander ^a   Kovalenko, Sergey ^a   Katsev, Andrew ^b   Komarovska Porokhnyavets, Elena ^c   Novikov, Vladimir ^c   Chekotilo, Aleksey ^d  

^a ZAPORIZHZHIA STATE MEDICAL UNIVERSITY   (Ukraine)

^b V I VERNADSKY CRIMEAN FEDERAL UNIVERSITY   (Russian Federation)

^c LVIV POLYTECHNIC NATIONAL UNIVERSITY   (Ukraine)

^d ENAMINE LTD   (Ukraine)

Author keywords

2 thio 1,2,4 triazolo 1,5 c quinazoline; Antifungal; Antimicrobial; Bioluminescence; Lipophilicity

Indexed keywords

([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)ACETIC ACID; ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)ACETIC ACID ETHYL ESTER; ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)ACETIC ACID METHYL ESTER; 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID; 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID METHYL ESTER; 3 (2,4 DICHLOROPHENYL) 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID METHYL ESTER; 3 (3 METHYLPHENYL) 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID ETHYL ESTER; 3 (3 NITROPHENYL) 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID METHYL ESTER; 3 (4 BROMOPHENYL) 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID ETHYL ESTER; 3 (4 CHLOROPHENYL) 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID METHYL ESTER; 3 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID; 3 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID METHYL ESTER; 3 PHENYL 2 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PROPIONIC ACID ETHYL ESTER; 4 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)BUTYRIC ACID ETHYL ESTER; 5 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PENTANOIC ACID; 5 ([1,2,4]TRIAZOLO[1,5 C]QUINAZOLIN 2 YLTHIO)PENTANOIC ACID METHYL ESTER; ACETIC ACID DERIVATIVE; ESTER DERIVATIVE; GENTAMICIN; ITRACONAZOLE; MICONAZOLE; NYSTATIN; OXACILLIN; PROPIONIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; TETRACYCLINE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE; VANCOMYCIN;

ALKYLATION; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BIOLUMINESCENCE; CANDIDA; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DEGRADATION; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; ESTERIFICATION; INFRARED SPECTROSCOPY; LIPOPHILICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MYCOBACTERIUM; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; BACTERIA; FUNGI; INDICATORS AND REAGENTS; LIPIDS; LUMINESCENCE; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; PHOTOBACTERIUM; QUINAZOLINES; SOLUBILITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 66949129986     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.580     Document Type: Article

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