Effect of a local heating device on insulin and glucose pharmacokinetic profiles in an open-label, randomized, two-period, one-way crossover study in patients with type 1 diabetes using continuous subcutaneous insulin infusion

Clinical Therapeutics

Volumn 31, Issue 5, 2009, Pages 980-987

  Raz, Itamar ^a   Weiss, Ram ^a   Yegorchikov, Yevgeny ^b   Bitton, Gabriel ^b   Nagar, Ron ^b   Pesach, Benny ^b  

^a HEBREW UNIVERSITY   (Israel)

^b InsuLine Medical Ltd   (Israel)

Author keywords

absorption; heating; insulin; pharmaco dynamics; pharmacokinetics

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; INSULIN ASPART; INSULIN LISPRO;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BODY MASS; CAUCASIAN; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; FEMALE; FEVER; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEATING; HUMAN; INJECTION SITE; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN PUMP; MALE; MAXIMUM PLASMA CONCENTRATION; NUTRITIONAL TOLERANCE; PATIENT MONITORING; POSTPRANDIAL STATE; RANDOMIZED CONTROLLED TRIAL; STOMACH PAIN; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT OUTCOME; WARMING;

ADOLESCENT; ADULT; AGED; AREA UNDER CURVE; BLOOD GLUCOSE; CROSS-OVER STUDIES; DIABETES MELLITUS, TYPE 1; EQUIPMENT AND SUPPLIES; FEMALE; GLUCOSE; HOT TEMPERATURE; HUMANS; INFUSIONS, SUBCUTANEOUS; INSULIN; INSULIN INFUSION SYSTEMS; MALE; MIDDLE AGED; PILOT PROJECTS; YOUNG ADULT;

EID: 66949118931     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2009.05.010     Document Type: Article

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