Accuracy of a commercial real-time polymerase chain reaction-based system for measurement of HIV RNA levels around the limit of quantification of the assay

Clinical Infectious Diseases

Volumn 48, Issue 11, 2009, Pages 1630-1631

  Amendola, Alessandra ^a   Milia, Maria Grazia ^a,b   Ghisetti, Valeria ^b   Brega, Carla ^a   Zaccaro, Paola ^a   Capobianchi, Maria R ^a  

^a NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^b AMEDEO DI SAVOIA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; DNA; VIRUS RNA;

BLOOD; CLINICAL EVALUATION; CLINICAL PRACTICE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FREEZING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LABORATORY TEST; LETTER; OUTPATIENT DEPARTMENT; PLASMA VOLUME; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY; VIRUS LOAD; ANALYSIS OF VARIANCE; EVALUATION; METHODOLOGY; NOTE; POLYMERASE CHAIN REACTION; REPRODUCIBILITY;

ANALYSIS OF VARIANCE; HIV INFECTIONS; HUMANS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; RNA, VIRAL; VIRAL LOAD;

EID: 66949118602     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/598990     Document Type: Letter

References (3)

1. Rebeiro PF, Kheshti A, Bebawy SS, et al. Increased detectability of plasma HIV-1 RNA after introduction of a new assay and altered specimen-processing procedures. Clin Infect Dis 2008;47:1354-7.
2. Nettles RE, Kieffer TL, Kwon P, et al. Intermittent HIV-1 viremia (blips) and drug resistance in patients receiving HAART. JAMA 2005;293:817-28.
3. Lee PK, Kieffer TL, Siliciano RF, Nettles RE. HIV-1 viral load blips are of limited clinical significance. J Antimicrob Chemother 2006;57: 803-5. 1631