-
1
-
-
74949135783
-
-
2009 ASCO Annual Meeting. www.asco.org/ASCO/Meetings/ASCO+Annual+Meeting
-
2009 ASCO Annual Meeting. www.asco.org/ASCO/Meetings/ASCO+Annual+Meeting
-
-
-
-
2
-
-
66849111193
-
Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics
-
Innocenti F, Kroetz DL, Schuetz E, et al: Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. J Clin Oncol 27:2604-2614, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 2604-2614
-
-
Innocenti, F.1
Kroetz, D.L.2
Schuetz, E.3
-
3
-
-
36048960109
-
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C study
-
Fuchs CS, Marshall J, Mitchell E, et al: Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C study. J Clin Oncol 25:4779-4786, 2007
-
(2007)
J Clin Oncol
, vol.25
, pp. 4779-4786
-
-
Fuchs, C.S.1
Marshall, J.2
Mitchell, E.3
-
4
-
-
42149178620
-
Clinical pharmacokinetics of irinotecan-based chemotherapy in colorectal cancer patients
-
Di Paolo A, Bocci G, Danesi R, et al: Clinical pharmacokinetics of irinotecan-based chemotherapy in colorectal cancer patients. Curr Clin Pharmacol 1:311-323, 2006
-
(2006)
Curr Clin Pharmacol
, vol.1
, pp. 311-323
-
-
Di Paolo, A.1
Bocci, G.2
Danesi, R.3
-
5
-
-
0034671387
-
Polymorphisms of UDP- glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
-
Ando Y, Saka H, Ando M, et al: Polymorphisms of UDP- glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis. Cancer Res 60:6921-6926, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 6921-6926
-
-
Ando, Y.1
Saka, H.2
Ando, M.3
-
6
-
-
0036025450
-
UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity
-
Iyer L, Das S, Janisch L, et al: UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. Pharmacogenomics J 2:43-47, 2002
-
(2002)
Pharmacogenomics J
, vol.2
, pp. 43-47
-
-
Iyer, L.1
Das, S.2
Janisch, L.3
-
7
-
-
2342459714
-
Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
-
Innocenti F, Undevia SD, Iyer L, et al: Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 22:1382-1388, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 1382-1388
-
-
Innocenti, F.1
Undevia, S.D.2
Iyer, L.3
-
8
-
-
4344632633
-
UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer
-
Marcuello E, Altés A, Menoyo A, et al: UGT1A1 gene variations and irinotecan treatment in patients with metastatic colorectal cancer. Br J Cancer 91:678-682, 2004
-
(2004)
Br J Cancer
, vol.91
, pp. 678-682
-
-
Marcuello, E.1
Altés, A.2
Menoyo, A.3
-
9
-
-
34548598459
-
UGT1A1*28 genotype and irinotecan-induced neutropenia: Dose matters
-
Hoskins JM, Goldberg RM, Qu P, et al: UGT1A1*28 genotype and irinotecan-induced neutropenia: Dose matters. J Natl Cancer Inst 99:1290-1295, 2007
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1290-1295
-
-
Hoskins, J.M.1
Goldberg, R.M.2
Qu, P.3
-
10
-
-
33744804311
-
Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin
-
Han JY, Lim HS, Shin ES, et al: Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin. J Clin Oncol 24:2237-2244, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 2237-2244
-
-
Han, J.Y.1
Lim, H.S.2
Shin, E.S.3
-
11
-
-
2942597859
-
Irinogenetics and UGT1A: From genotypes to haplotypes
-
Innocenti F, Ratain MJ: "Irinogenetics" and UGT1A: From genotypes to haplotypes. Clin Pharmacol Ther 75:495-500, 2004
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 495-500
-
-
Innocenti, F.1
Ratain, M.J.2
-
12
-
-
0042196122
-
Irinotecan pathway genotype analysis to predict pharmacokinetics
-
Mathijssen RH, Marsh S, Karlsson MO, et al: Irinotecan pathway genotype analysis to predict pharmacokinetics. Clin Cancer Res 9:3246-3253, 2003
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3246-3253
-
-
Mathijssen, R.H.1
Marsh, S.2
Karlsson, M.O.3
-
14
-
-
53649102831
-
Clinical and pharmacogenetic factors associated with irinotecan toxicity
-
Kweekel D, Guchelaar HJ, Gelderblom H: Clinical and pharmacogenetic factors associated with irinotecan toxicity. Cancer Treat Rev 34:656-669, 2008
-
(2008)
Cancer Treat Rev
, vol.34
, pp. 656-669
-
-
Kweekel, D.1
Guchelaar, H.J.2
Gelderblom, H.3
-
15
-
-
33745972934
-
The role of UGT1A1*28 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer
-
Toffoli G, Cecchin E, Corona G, et al: The role of UGT1A1*28 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer. J Clin Oncol 24:3061-3068, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 3061-3068
-
-
Toffoli, G.1
Cecchin, E.2
Corona, G.3
-
16
-
-
43949093319
-
A genotype-directed phase I study of irinotecan in advanced cancer patients
-
suppl; abstr 2502, 97s
-
Innocenti F, Janisch L, Das S, et al: A genotype-directed phase I study of irinotecan in advanced cancer patients. J Clin Oncol 25:97s, 2007 (suppl; abstr 2502)
-
(2007)
J Clin Oncol
, vol.25
-
-
Innocenti, F.1
Janisch, L.2
Das, S.3
-
17
-
-
34447551611
-
Cigarette smoking and irinotecan treatment: Pharmacokinetic interaction and effects on neutropenia
-
van der Bol JM, Mathijssen RH, Loos WJ, et al: Cigarette smoking and irinotecan treatment: Pharmacokinetic interaction and effects on neutropenia. J Clin Oncol 25:2719-2726, 2007
-
(2007)
J Clin Oncol
, vol.25
, pp. 2719-2726
-
-
van der Bol, J.M.1
Mathijssen, R.H.2
Loos, W.J.3
-
18
-
-
40949156763
-
Lopinavir-ritonavir dramatically affects the pharmacokinetics of irinotecan in HIV patients with Kaposi's sarcoma
-
Corona G, Vaccher E, Sandron S, et al: Lopinavir-ritonavir dramatically affects the pharmacokinetics of irinotecan in HIV patients with Kaposi's sarcoma. Clin Pharmacol Ther 83:601-606, 2008
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 601-606
-
-
Corona, G.1
Vaccher, E.2
Sandron, S.3
-
19
-
-
22544435261
-
CYP3A probes can quantitatively predict the in vivo kinetics of other CYP3A substrates and can accurately assess CYP3A induction and inhibition
-
Kharasch ED, Thummel KE, Watkins PB: CYP3A probes can quantitatively predict the in vivo kinetics of other CYP3A substrates and can accurately assess CYP3A induction and inhibition. Mol Interv 5:151-153, 2005
-
(2005)
Mol Interv
, vol.5
, pp. 151-153
-
-
Kharasch, E.D.1
Thummel, K.E.2
Watkins, P.B.3
-
20
-
-
7944233687
-
Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes
-
Mathijssen RH, de Jong FA, van Schaik RH, et al: Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes. J Natl Cancer Inst 96:1585-1592, 2004
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1585-1592
-
-
Mathijssen, R.H.1
de Jong, F.A.2
van Schaik, R.H.3
-
22
-
-
0036137897
-
Impact of body-size measures on irinotecan clearance: Alternative dosing recommendations
-
Mathijssen RH, Verweij J, de Jonge MJ, et al: Impact of body-size measures on irinotecan clearance: Alternative dosing recommendations. J Clin Oncol 20:81-87, 2002
-
(2002)
J Clin Oncol
, vol.20
, pp. 81-87
-
-
Mathijssen, R.H.1
Verweij, J.2
de Jonge, M.J.3
-
23
-
-
35648976118
-
The diploid genome sequence of an individual human
-
Levy S, Sutton G, Ng PC, et al: The diploid genome sequence of an individual human. PLoS Biol 5:e254, 2007
-
(2007)
PLoS Biol
, vol.5
-
-
Levy, S.1
Sutton, G.2
Ng, P.C.3
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