Letter metastable processes investigated on an orthogonal-axis time-of-flight instrument: Mass-scale calibration and application

European Journal of Mass Spectrometry

Volumn 15, Issue 3, 2009, Pages 431-437

  Winter, Julien De ^a   Goffin, Anne Lise ^a   Coulembier, Olivier ^a   Dubois, Philippe ^a   Flammang, Robert ^a   Gerbaux, Pascal ^a  

^a UNIVERSITY OF MONS   (Belgium)

Author keywords

Cid; End group specific dissociation; Metastable ions; Nanotechnology; Pla im publications llp 2009 all rights reserved; Polymers; Tof analyzer

Indexed keywords

ION; ORGANOSILICON DERIVATIVE; POLYESTER; POLYHEDRALOLIGOSILSESQUIOXANE; POLYLACTIDE; SODIUM;

CALIBRATION; CHEMISTRY; ECONOMICS; ELECTROSPRAY MASS SPECTROMETRY; LETTER; METHODOLOGY; TIME;

CALIBRATION; IONS; ORGANOSILICON COMPOUNDS; POLYESTERS; SODIUM; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS;

EID: 66849131097     PISSN: 14690667     EISSN: None     Source Type: Journal    
DOI: 10.1255/ejms.973     Document Type: Article

References (18)

1. A.-L. Goffin, E. Duquesne, S. Moins, M. Alexandre and P. Dubois, "New organic-inorganic nanohybrids via ring opening polymerization of (di) lactones initiated by functionalized polyhedral oligomeric silsesquioxane", Eur. Polym J. 43, 4103 (2007). doi: 10.1016/j.eurpo-Lymj.2007.07.041
2. Y. Q. Zhao and D. A. Schiraldi. "Thermal and mechanical properties of polyhedral oligomeric silsesquioxane (POSS)/polycarbonate composites", Polymer 46, 11640 (2005).
3. S. Bourbigot, S. Duquesne and C. Jama, "Polymer nanocomposites: How to reach low flammability?", Macromol. Symp. 233, 180 (2006). doi: 10.1002/masy.200690016
4. L. Matejka, A. Strachota, J. Plestil, P. Whelan, M. Steinhart and M. Slouf, "Epoxy networks reinforced with polyhedral oligomeric silsesquioxanes (POSS). Structure and morphology", Macromolecuies 37, 94-49 (2004). doi: 10.1021/ma0484577
5. AminopropylheptakislisobutyDPOSS (P0SS-NH2, 97%) was purchased from Hybrid Plastics.
6. -1. Typical ESI conditions were: capillary voltage, 3.1 kV; cone voltage, 15V; source temperature, 80°C; desolvation temperature, 120°C. Dry nitrogen was used as the ESI gas. For the recording of the single-stage ESI-MS spectra, the quadrupole (rf-only mode) was set to pass ions from 50Th to 1000Th, and all ions were transmitted into the pusher region of the time-of-flight analyzer where they were mass analyzed with 1 s integration time. Data were acquired in continuum mode until acceptable averaged data were obtained. For the ESI-MS/MS CID experiments, the ions of interest are mass-selected by the quadrupole mass filter. The precursor ion resolution is adjusted to select only the monoisotopic signal amongst the complete isotopic cluster. The selected ions are then submitted to collision against argon in the rf-only hexapole collision cell. All ions coming out of the hexapole cell, either the fragments or the non dissociated precursor ions, are finally mass-measured with the oa-ToF analyzer.
7. T. J. P. Naven, D. J. Harvey. J. Brown and G. Critchley, "Fragmentation of complex carbohydrates following ionization by matrix-assisted laser desorption with an instrument fitted with time-lag focusing", Rapid Commun. Mass Spectrom. 11, 1681 (1997). doi: 10.1002/(SICI) 1097-0231 (19971015) 11:15<1681::AID-RCM34>3.0. CO;2-0
8. R. S. Brown and J. J. Lennon, "Sequence-specific fragmentation of matrix-assisted Laser-desorbed protein peptide ions", Anal. Chem. 67, 3990 (1995). doi: 10.1021/ac00117a027
9. R. Kaufmann, B. Spengler and F. Lutzenkirchen, "Mass-spectrometric sequencing of Linear peptides by product-ion analysis in a reflectron time-of-flight massspectrometer using matrix-assisted laser-desorption ionization", Rapid Commun. Mass Spectrom. 7, 702 (1993). doi: 10.1002/rcm. 1290071010
10. R. G. Cooks, J. H. Beynon, R. M. Caprioli and G. R. Lester, Metastable Ions. Elsevier Scientific Publishing Company, Amsterdam, The Netherlands (1973).
11. D. J. Harvey, A. P. Hunter, R. H. Bateman, J. Brown and G. Critchley, "Relationship between in-source and post-source fragment ions in the matrix-assisted laser desorption (ionization) mass spectra of carbohydrates recorded with reflectron time-of-flight mass spectrometers", Int. J. Mass Spectrom. 188, 131 (1999). doi: 10.1016/S1387-38061991000U-7
12. C. Versluis, A. Van der Staaij, E. Stokvis, A. J. R. Heck and B. De Craene, "Metastable ion formation and disparate charge separation in the gas-phase dissection of protein assemblies studied by orthogonal time-of-flight mass spectrometry", J. Am. Soc. Mass Spectrom. 12, 329 (2001). doi: 10.1016/S1044-0305100100227-0
13. 2O adduct formation and gas-phase reactions in the collision cell", J. Am. Soc. Mass Spectrom. 16, 1291 (2005). doi: 10.1016/j.jasms.2005.03.026
14. C. Collette and E. De Pauw, "Calibration of the internal energy distribution of ions produced by electrospray", Rapid Commun. Mass Spectrom. 12, 165 (1998). doi: 10.1002/(SICI) 1097-0231 (19980227) 12:4<165::AID-RCM140>3.0. CO;2-1
15. 3, δ (ppm)): 0.8-1 (t, 3H), 1.3 (s, 28H), 1.5-1.9 (d, 3 (2n + 1) H), 3.8 (m, 2H), 4.4 (q, 1H; CH-OH), 5-5.3 (q, 2nH), 6.2 (1H; NH).
16. I. Osaka, M. Watanabe, M. Takama, M. Murakami and R. Arakawa, "Characterization of linear and cyclic polylactic acids and their solvolys products by electrospray ionization mass spectrometry", J. Mass. Spectrom. 41, 1369 (2006). doi: 10.1002/jms.1110
17. G. Adamus, "Structural analysis of poly ((R, S)-3- hydroxybutyrate-co-L-lactide) copolyesters by electrospray ionization ion trap mass spectrometry", Rapid Commun. Mass Spectrom. 21, 2477 (2007). doi: 10.1002/rcm.3111
18. J. De Winter, 0. Coulembier, P. Marsal, J. Cornil, P. Dubois and P. Gerbaux, in preparation.