Beneficial role of pancreatic microenvironment for angiogenesis in transplanted pancreatic islets

Cell Transplantation

Volumn 18, Issue 1, 2009, Pages 23-30

  Lau, Joey ^a   Kampf, Caroline ^a   Mattsson, Göran ^a   Nyqvist, Daniel ^b   Köhler, Martin ^b   Berggren, Per Olof ^b   Carlsson, Per Ola ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Angiogenesis; Bandeiraea simplicifolia; Engraftment; Islet graft; Pancreas

Indexed keywords

ANGIOPOIETIN RECEPTOR; GREEN FLUORESCENT PROTEIN; LECTIN; YELLOW FLUORESCENT PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL DIAMETER; CAPILLARY; CELL COUNT; CELL CULTURE; CELL EXPANSION; CELL ISOLATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HOST; KIDNEY CAPSULE; MALE; MICROENVIRONMENT; MOUSE; NONHUMAN; PANCREAS; PANCREAS BLOOD FLOW; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECIPIENT; REPORTER GENE; SOMATIC CELL; TISSUE SECTION; TISSUE STRUCTURE; TRANSGENE;

ANIMALS; ENDOTHELIAL CELLS; GRAFT SURVIVAL; HUMANS; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LUMINESCENT PROTEINS; MICE; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC;

BANDEIRAEA SIMPLICIFOLIA; MUS; MUS MUSCULUS;

EID: 66849109257     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368909788237131     Document Type: Article

References (40)

1. Adams, R. H. Vascular patterning by Eph receptor tyrosine kinases and ephrins. Semin. Cell Dev. Biol. 13(1):55-60; 2002.
2. Bennet, W.; Sundberg, B.; Groth, C. G.; Brendel, M. D.; Brandhorst, D.; Brandhorst, H.; Bretzel, R. G.; Elgue, G.; Larsson, R.; Nilsson, B.; Korsgren, O. Incompatibility between human blood and isolated islets of Langerhans: A finding with implications for clinical intraportal islet transplantation? Diabetes 48(10):1907-1914; 1999.
3. Biarnes, M.; Montolio, M.; Nacher, V.; Raurell, M.; Soler, J.; Montanya, E. Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes 51(1):66-72; 2002. (Pubitemid 34517981)
4. Bonner-Weir, S. Morphological evidence for pancreatic polarity of beta-cell within islets of Langerhans. Diabetes 37(5):616-621; 1988. (Pubitemid 18116250)
5. Brissova, M.; Fowler, M.; Wiebe, P.; Shostak, A.; Shiota, M.; Radhika, A.; Lin, P. C.; Gannon, M.; Powers, A. C. Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets. Diabetes 53(5):1318-1325; 2004.
6. Carlsson, P. O.; Palm, F.; Andersson, A.; Liss, P. Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 50(3):489-495; 2001. (Pubitemid 32195212)
7. Carlsson, P. O.; Palm, F.; Mattsson, G. Low revascularization of experimentally transplanted human pancreatic islets. J. Clin. Endocrinol. Metab. 87(12):5418-5423; 2002.
8. Carmeliet, P. Blood vessels and nerves: common signals, pathways and diseases. Nat. Rev. Genet. 4(9):710-720; 2003.
9. Contreras, J. L.; Smyth, C. A.; Eckstein, C.; Bilbao, G.; Thompson, J. A.; Young, C. J.; Eckhoff, D. E. Peripheral mobilization of recipient bone marrow-derived endothelial progenitor cells enhances pancreatic islet revascularization and engraftment after intraportal transplantation. Surgery 134(2):390-398; 2003.
10. Davalli, A. M.; Scaglia, L.; Zangen, D. H.; Hollister, J.; Bonner-Weir, S.; Weir, G. C. Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45(9):1161-1167; 1996.
11. Emamaullee, J. A.; Shapiro, A. M. Factors influencing the loss of beta-cell mass in islet transplantation. Cell Transplant. 16(1):1-8; 2007.
12. Hayek, A.; Beattie, G. M. Intrapancreatic islet transplantation in experimental diabetes in the rat. Metabolism 41(12):1367-1369; 1992.
13. Jansson, L.; Carlsson, P. O. Graft vascular function after transplantation of pancreatic islets. Diabetologia 45(6):749-763; 2002.
14. Konstantinova, I.; Nikolova, G.; Ohara-Imaizumi, M.; Meda, P.; Kucera, T.; Zarbalis, K.; Wurst, W.; Nagamatsu, S.; Lammert, E. EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. Cell 129(2):359-370; 2007. (Pubitemid 46574973)
15. Lai, Y.; Schneider, D.; Kidszun, A.; Hauck-Schmalenberger, I.; Breier, G.; Brandhorst, D.; Brandhorst, H.; Iken, M.; Brendel, M. D.; Bretzel, R. G.; Linn, T. Vascular endothelial growth factor increases functional beta-cell mass by improvement of angiogenesis of isolated human and murine pancreatic islets. Transplantation 79(11):1530-1536; 2005. (Pubitemid 40847584)
16. Lau, J.; Mattsson, G.; Carlsson, C.; Nyqvist, D.; Kohler, M.; Berggren, P. O.; Jansson, L.; Carlsson, P. O. Implantation site-dependent dysfunction of transplanted pancreatic islets. Diabetes 56(6):1544-1550; 2007.
17. Lau, J.; Carlsson, P. O. Low revascularization of human islets when experimentally transplanted into the liver. Transplantation 87(3):322-325; 2009.
18. Linn, T.; Schneider, K.; Hammes, H. P.; Preissner, K. T.; Brandhorst, H.; Morgenstern, E.; Kiefer, F.; Bretzel, R. G. Angiogenic capacity of endothelial cells in islets of Langerhans. FASEB J. 17(8):881-883; 2003.
19. Lou, J.; Triponez, F.; Oberholzer, J.; Wang, H.; Yu, D.; Buhler, L.; Cretin, N.; Mentha, G.; Wollheim, C. B.; Morel, P. Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells. Diabetes 48(9):1773-1778; 1999. (Pubitemid 29415196)
20. Maffei, A.; Liu, Z.; Witkowski, P.; Moschella, F.; Del Pozzo, G.; Liu, E.; Herold, K.; Winchester, R. J.; Hardy, M. A.; Harris, P. E. Identification of tissue-restricted transcripts in human islets. Endocrinology 145(10):4513-4521; 2004.
21. Mattsson, G.; Jansson, L.; Carlsson, P. O. Decreased vascular density in mouse pancreatic islets after transplantation. Diabetes 51(5):1362-1366; 2002.
22. Mattsson, G.; Jansson, L.; Nordin, A.; Andersson, A.; Carlsson, P. O. Evidence of functional impairment of syngeneically transplanted mouse pancreatic islets retrieved from the liver. Diabetes 53(4):948-954; 2004.
23. Mattsson, G.; Jansson, L.; Nordin, A.; Carlsson, P. O. Impaired revascularization of transplanted mouse pancreatic islets is chronic and glucose-independent. Transplantation 75(5):736-739; 2003.
24. Menger, M. D.; Jaeger, S.; Walter, P.; Feifel, G.; Hammersen, F.; Messmer, K. Angiogenesis and hemodynamics of microvasculature of transplanted islets of Langerhans. Diabetes 38(Suppl. 1):199-201; 1989.
25. Miyawaki, A.; Llopis, J.; Heim, R.; McCaffery, J. M.; Adams, J. A.; Ikura, M.; Tsien, R. Y. Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature 388(6645):882-887; 1997.
26. Navarro-Alvarez, N.; Rivas-Carrillo, J. D.; Soto-Gutierrez, A.; Yuasa, T.; Okitsu, T.; Noguchi, H.; Matsumoto, S.; Takei, J.; Tanaka, N.; Kobayashi, N. Reestablishment of microenvironment is necessary to maintain in vitro and in vivo human islet function. Cell Transplant. 17(1-2):111-119; 2008.
27. Nyqvist, D.; Kohler, M.; Wahlstedt, H.; Berggren, P. O. Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts. Diabetes 54(8):2287-2293; 2005.
28. Nyqvist, D.; Mattsson, G.; Kohler, M.; Lev-Ram, V.; Andersson, A.; Carlsson, P. O.; Nordin, A.; Berggren, P. O.; Jansson, L. Pancreatic islet function in a transgenic mouse expressing fluorescent protein. J. Endocrinol. 186(2):333-341; 2005. (Pubitemid 41167402)
29. Parr, E. L.; Bowen, K. M.; Lafferty, K. J. Cellular changes in cultured mouse thyroid glands and islets of Langerhans. Transplantation 30(2):135-141; 1980.
30. Pries, A. R.; Kuebler, W. M. Normal endothelium. In: Moncada, S.; Higgs, A., ed. Handbook of experimental pharmacology. Heidelberg, Germany: Springer-Verlag; 2006:176/I:1-40.
31. Ribatti, D.; Nico, B.; Vacca, A.; Roncali, L.; Dammacco, F. Endothelial cell heterogeneity and organ specificity. J. Hematother. Stem Cell Res. 11(1):81-90; 2002.
32. Stagner, J. I.; Mokshagundam, S. P.; Samols, E. Induction of mild hypoglycemia by islet transplantation to the pancreas. Transplant. Proc. 30(2):635-636; 1998.
33. Stagner, J. I.; Rilo, H. L.; White, K. K. The pancreas as an islet transplantation site. Confirmation in a syngeneic rodent and canine autotransplant model. JOP 8(5):628-636; 2007.
34. Tsai, P. S.; Friedman, B.; Ifarraguerri, A. I.; Thompson, B. D.; Lev-Ram, V.; Schaffer, C. B.; Xiong, Q.; Tsien, R. Y.; Squier, J. A.; Kleinfeld, D. All-optical histology using ultrashort laser pulses. Neuron 39(1):27-41; 2003. (Pubitemid 36830946)
35. Vajkoczy, P.; Olofsson, A. M.; Lehr, H. A.; Leiderer, R.; Hammersen, F.; Arfors, K. E.; Menger, M. D. Histogenesis and ultrastructure of pancreatic islet graft microvasculature. Evidence for graft revascularization by endothelial cells of host origin. Am. J. Pathol. 146(6):1397-1405; 1995.
36. Vu, T. H.; Alemayehu, Y.; Werb, Z. New insights into saccular development and vascular formation in lung allografts under the renal capsule. Mech. Dev. 120(3):305-313; 2003.
37. Wang, B.; Xiao, Y.; Ding, B. B.; Zhang, N.; Yuan, X.; Gui, L.; Qian, K. X.; Duan, S.; Chen, Z.; Rao, Y.; Geng, J. G. Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity. Cancer Cell 4(1):19-29; 2003.
38. Weibel, E. R. Stereological methods. In: Weibel, E. R., ed. Practical methods for biological morphometry Vol. 1. San Francisco, CA: Academic Press; 1979:101-161.
39. Yao, V. J.; Ozawa, M. G.; Trepel, M.; Arap, W.; McDonald, D. M.; Pasqualini, R. Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection. Am. J. Pathol. 166(2):625-636; 2005.
40. Zhang, N.; Richter, A.; Suriawinata, J.; Harbaran, S.; Altomonte, J.; Cong, L.; Zhang, H.; Song, K.; Meseck, M.; Bromberg, J.; Dong, H. Elevated vascular endothelial growth factor production in islets improves islet graft vascularization. Diabetes 53(4):963-970; 2004. (Pubitemid 38436608)