The expression of SnoN in normal human skin and cutaneous keratinous neoplasms

International Journal of Dermatology

Volumn 48, Issue 6, 2009, Pages 579-583

  Zhang, Xiaoyong ^a   Egawa, Kiyofumi ^a   Xie, Yong ^a   Ihn, Hironobu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; POLYCLONAL ANTIBODY; SKI NOVEL RELATED PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BASAL CELL; BASAL CELL CARCINOMA; CANCER INVASION; CELL DIFFERENTIATION; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SEBORRHEIC KERATOSIS; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA;

CARCINOMA, BASAL CELL; CARCINOMA, SQUAMOUS CELL; CELL DIFFERENTIATION; DERMIS; EPIDERMIS; HAIR FOLLICLE; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATOSIS, ACTINIC; PROTO-ONCOGENE PROTEINS; SKIN; SKIN NEOPLASMS; SWEAT GLANDS;

EID: 66849106525     PISSN: 00119059     EISSN: 13654632     Source Type: Journal    
DOI: 10.1111/j.1365-4632.2009.03685.x     Document Type: Article

References (13)

1. Nagase T, Nomura N, Ishii S. Complex formation between proteins encoded by the ski gene family. J Biol Chem 1993; 268: 13, 710-13, 716.
2. Pearson-White S, Crittenden R. Proto-oncogene Sno expression, alternative isoforms and immediate early serum response. Nucleic Acids Res 1997; 25: 2930-2937.
3. Pearson-White S. SnoI, a novel alternatively spliced isoform of the ski proto-oncogene homolog, sno. Nucleic Acids Res 1993; 21: 4632-4638.
4. Nomura N, Sasamoto S, Ishii S, et al. Isolation of human cDNA clones of ski and the ski-related gene, Sno. Nucleic Acids Res 1989; 17: 5489-5500.
5. Zhang F, Lundin M, Ristimaki A, et al. Ski-related novel protein N (SnoN), a negative controller of transforming growth factor-β signaling, is a prognostic marker in estrogen receptor-positive breast carcinomas. Cancer Res 2003; 63: 5005-5010.
6. Boyer PL, Colmenares C, Stavnezer E, et al. Sequence and biological activity of chicken SnoN cDNA clones. Oncogene 1993; 8: 457-466.
7. Fukuchi M, Nakajima M, Fukai Y, et al. Increased expression of c-Ski as a co-repressor in transforming growth factor-β signaling correlates with progression of esophageal squamous cell carcinoma. Int J Cancer 2004; 108: 818-824.
8. Poser I, Rothhammer T, Dooley S, et al. Characterization of Sno expression in malignant melanoma. Int J Oncol 2005; 26: 1411-1417.
9. Choi Y, Fuchs E. TGF-β and retinoic acid: Regulators of growth and modifiers of differentiation in human epidermal cells. Cell Regul 1990; 1: 791-809.
10. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
11. Liu X, Sun Y, Weinberg RA, et al. Ski/Sno and TGF-β signaling. Cytokine Growth Factor Rev 2001; 12: 1-8.
12. He J, Tegen SB, Krawitz AR, et al. The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins. J Biol Chem 2003; 278: 30, 540-30, 547.
13. Rhim JS. Viruses, oncogenes, and cancer. Cancer Detect Prev 1988; 11: 139-149.