Joint effect of obesity and TNFA variability on asthma: Two international cohort studies

European Respiratory Journal

Volumn 33, Issue 5, 2009, Pages 1003-1009

  Castro Giner, F ^a   Kogevinas, M ^a,k   Imboden, M ^b,l   de Cid, R ^b,l   Jarvis, D ^c,l   Machler M ^b   Berger, W ^b   Burney, P ^c,l   Franklin, K A ^d,l   Gonzalez, J R ^a   Heinrich, J ^e,l   Janson, C ^f,l   Omenaas, E ^g   Pin, I ^h,l   Rochat, T ⁱ   Sunyer, J ^a   Wjst, M ^e,l   Anto J M ^a   Estivill, X ^j   Probst Hensch, N M ^j   Broglie, M ^l   Bunter M ^l   Gashi, D ^l   Armbruster, R ^l   Damm, T ^l   Egermann, U ^l   Gut, M ^l   Maier, L ^l   Vogelin A ^l   Walter, L ^l   Jud, D ^l   Lutz, N ^l   Ares, M ^l   Bennour, M ^l   Galobardes, B ^l   Namer, E ^l   Baumberger, B ^l   Boccia Soldati, S ^l   Gehrig Van Essen, E ^l   Ronchetto, S ^l   Bonvin, C ^l   Burrus, C ^l   Blanc, S ^l   Ebinger, A V ^l   Fragniere M L ^l   Jordan, J ^l   Gimmi, R ^l   Kourkoulos, N ^l   Schafroth, U ^l   Bauer, N ^l   Baehler, D ^l   Gabriel, C ^l   Nilly, R ^l   Ackermann Liebrich, U ^l   Gaspoz, J M ^l   Leuenberger, P ^l   Liu, L J S ^l   Schindler, C ^l   Barthelemy J C ^l   Bettschart, R ^l   Bircher, A ^l   Bolognini, G ^l   Brandli O ^l   Brutsche, M ^l,l   Burdet, L ^l   Frey, M ^l   Gerbase, M W ^l   Gold, D ^l   Karrer, W ^l   Keller, R ^l   Knopfli B ^l   Kunzli N ^l   Neu, U ^l   Nicod, L ^l   Pons, M ^l   Russi, E ^l   Schmid Grendelmeyer, P ^l   Schwartz, J ^l   Straehl, P ^l   Tschopp, J M ^l   von Eckardstein, A ^l   Zellweger, J P ^l   Zemp Stutz, E ^l   Bridevaux, P O ^l   Curjuric, I ^l   Downs, S H ^l   Felber Dietrich, D ^l   Gemperli, A ^l   Keidel, D ^l   Staedele Kessler, P ^l   Thun, G A ^l   Abramson, M ^l   Woods, R ^l   Walters, E H ^l   Thien, F ^l   Benke, G ^l   Vermeire, P ^l   Weyler, J ^l   Van Sprundel, M ^l   Nelen, V ^l   Jogi, R ^l   Soon, A ^l   Neukirch, F ^l   Leynaert, B ^l   Liard, R ^l   Zureik, M ^l   Ferran Quentin, J ^l   Frye, C ^l   Meyer, I ^l   Gislason, T ^l   Bugiani, M ^l   Piccioni, P ^l   Carosso, A ^l   Arossa, W ^l   Caria, E ^l   Castiglioni, G ^l   Migliore, E ^l   Romano, C ^l   Fabbro, D ^l   Ciccone, G ^l   Magnani, C ^l   Dalmasso, P ^l   Bono, R ^l   Gigli, G ^l   Giraudo, A ^l   Brussino, M C ^l   Bucca, C ^l   Rolla, G ^l   de Marco, R ^l   Verlato, G ^l   Zanolin, E ^l   Accordini, S ^l   Poli, A ^l   Lo Cascio, V ^l   Ferrari, M ^l   Marinoni, A ^l   Villani, S ^l   Ponzio, M ^l   Frigerio, F ^l   Comelli, M ^l   Grassi, M ^l   Cerveri, I ^l   Corsico, A ^l   Schouten, J ^l   Gulsvik, A ^l   Svanes, C ^l   Laerum, B ^l   Zock, J P ^l   Basagana, X ^l   Jaen, A ^l   Burgos, F ^l   Maldonado, J ^l   Pereira, A ^l   Sanchez, J L ^l   Martinez Moratalla Rovira, J ^l   Almar, E ^l   Muniozguren, N ^l   Urritia, I ^l   Payo, F ^l   Boman, G ^l   Norback, D ^l   Gunnbjornsdottir, M ^l   Toren, K ^l   Lillienberg, L ^l   Dahlman Hoglund A ^l   Sundberg, R ^l   Norrman, E ^l   Soderberg, M ^l   Lundback, B ^l   Forsberg, B ^l   Nystrom, L ^l   Dibbert, B ^l   Hazenkamp, M ^l   Chinn, S ^l   Harrison, B ^l   Hall, R ^l   Seaton, D ^l   Osborne, M ^l   Buist, S ^l   Vollmer, W ^l   Johnson, L ^l   more..

^a INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

^f UPPSALA UNIVERSITY   (Sweden)

^g HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^h GRENOBLE UNIVERSITY HOSPITAL   (France)

ⁱ GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^j CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^k UNIVERSITY OF CRETE   (Greece)

^l Universitat Pompeu Fabra ^*

more..

Author keywords

Asthma; Atopy; Genetic polymorphism; Obesity; Tumour necrosis factor a

Indexed keywords

LYMPHOTOXIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 66749175772     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00140608     Document Type: Article

References (39)

1. Ford ES. The epidemiology of obesity and asthma. J Allergy Clin Immunol 2005; 115: 897-909.
2. Matricardi PM, Gruber C, Wahn U, Lau S. The asthma- obesity link in childhood: open questions, complex evidence, a few answers only. Clin Exp Allergy 2007; 37: 476-484.
3. Chinn S. Asthma and obesity: where are we now? Thorax 2003; 58: 1008-1010.
4. Beuther DA, Weiss ST, Sutherland ER. Obesity and asthma. Am J Respir Crit Care Med 2006; 174: 112-119.
5. Weiss ST. Obesity: insight into the origins of asthma. Nat Immunol 2005; 6: 537-539.
6. Tantisira KG, Weiss ST. Complex interactions in complex traits: obesity and asthma. Thorax 2001; 56: Suppl. 2, ii64-ii73.
7. Shore SA. Obesity and asthma: lessons from animal models. J Appl Physiol 2007; 102: 516-528.
8. Hersoug LG, Linneberg A. The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance? Allergy 2007; 62: 1205-1213.
9. Hallstrand TS, Fischer ME, Wurfel MM, Afari N, Buchwald D, Goldberg J. Genetic pleiotropy between asthma and obesity in a community-based sample of twins. J Allergy Clin Immunol 2005; 116: 1235-1241.
10. Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor-a promoter on transcriptional activation. Proc Natl Acad Sci USA 1997; 94: 3195-3199.
11. Messer G, Spengler U, Jung MC, et al. Polymorphic structure of the tumor necrosis factor (TNF) locus: an Ncol polymorphism in the first intron of the human TNF-b gene correlates with a variant amino acid in position 26 and a reduced level of TNF-b production. J Exp Med 1991;173: 209-219.
12. Castro-Giner F, Kogevinas M, Machler M, et al. TNFA - 308G.A in two international population-based cohorts and risk of asthma. Eur Respir J 2008; 32: 350-361.
13. Burney PG, Luczynska C, Chinn S, Jarvis D. The European Community RespiratoryHealth Survey. Eur Respir J 1994;7: 954-960.
14. Jarvis D, Chinn S, Potts J, Burney P. Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey. Clin Exp Allergy 2002; 32: 831-837.
15. Martin BW, Ackermann-Liebrich U, Leuenberger P, et al. SAPALDIA: methods and participation in the cross- sectional part of the Swiss Study on Air Pollution and Lung Diseases in Adults. Soz Praventivmed 1997; 42: 67-84.
16. Ackermann-Liebrich U, Kuna-Dibbert B, Probst-Hensch NM, et al. Follow-up of the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA 2) 19912003: methods and characterization of participants. Soz Praventivmed 2005; 50: 245-263.
17. Kogevinas M, Zock JP, Jarvis D, et al. Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II). Lancet 2007; 370: 336-341.
18. Gonzalez JR, Armengol L, Sole X, et al. SNPassoc: an R package to perform whole genome association studies. Bioinformatics 2007; 23: 644-645.
19. R Development Core Team. R: A language and environment for statistical computing. Vienna, R Foundation for Statistical Computing, 2007. www.R-project.org
20. Wigginton JE, Cutler DJ, Abecasis GR. A note on exact tests of Hardy-Weinberg equilibrium. Am J Hum Genet 2005; 76: 887-893.
21. Devlin B, Roeder K. Genomic control for association studies. Biometrics 1999; 55: 997-1004.
22. Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006; 38: 904-909.
23. Chinn S, Downs SH, Anto JM, et al. Incidence of asthma and net change in symptoms in relation to changes in obesity. Eur Respir J 2006; 28: 763-771.
24. Vortmann M, Eisner MD. BMI and health status among adults with asthma. Obesity (Silver Spring) 2008; 16:146-152.
25. Braback L, Hjern A, Rasmussen F. Body mass index, asthma and allergic rhinoconjunctivitis in Swedish conscripts - a national cohort study over three decades. Respir Med 2005; 99: 1010-1014.
26. Guerra S, Sherrill DL, Bobadilla A, Martinez FD, Barbee RA. The relation of body mass index to asthma, chronic bronchitis, and emphysema. Chest 2002; 122: 1256-1263.
27. Schachter LM, Salome CM, Peat JK, Woolcock AJ. Obesity is a risk for asthma and wheeze but not airway hyperresponsiveness. Thorax 2001; 56: 4-8.
28. Sookoian SC, Gonzalez C, Pirola CJ. Meta-analysis on the G-308A tumor necrosis factor-a gene variant and pheno- types associated with the metabolic syndrome. Obes Res 2005; 13: 2122-2131.
29. Li YP, Lecker SH, Chen Y, Waddell ID, Goldberg AL, Reid MB. TNF-a increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k. FASEB J 2003; 17: 1048-1057.
30. Tsigos C, Kyrou I, Chala E, et al. Circulating tumor necrosis factor-a concentrations are higher in abdominal versus peripheral obesity. Metabolism 1999; 48: 1332-1335.
31. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-a: direct role in obesity-linked insulin resistance. Science 1993; 259: 87-91.
32. Gosset P, Tsicopoulos A, Wallaert B, Joseph M, Capron A, Tonnel AB. Tumor necrosis factor-a and interleukin-6 production by human mononuclear phagocytes from allergic asthmatics after IgE-dependent stimulation. Am Rev Respir Dis 1992; 146: 768-774.
33. Beuther DA, Sutherland ER. Overweight, obesity, and incident asthma: a meta-analysis of prospective epi- demiologic studies. Am J Respir Crit Care Med 2007; 175:661-666.
34. Gilliland FD, Berhane K, Islam T, et al. Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol 2003; 158: 406-415.
35. Kronander UN, Falkenberg M, Zetterstrom O. Prevalence and incidence of asthma related to waist circumference and BMI in a Swedish community sample. Respir Med 2004;98: 1108-1116.
36. von Mutius E, Schwartz J, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III. Thorax 2001; 56: 835-838.
37. Jarvis D, Chinn S, Potts J, Burney P. Association of body mass index with espiratory symptoms and atopy: results from the European Community Respiratory Health Survey. Clin Exp Allergy 2002; 32: 831-837.
38. Olafsdottir IS, Gislason T, Thjodleifsson B, et al. C reactive protein levels are increased in non-allergic but not allergic asthma: a multicentre epidemiological study. Thorax 2005;60: 451-454.
39. de Koning L, Merchant AT, Pogue J, Anand SS. Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Eur Heart J 2007; 28: 850-856.