Calpain-3 is activated following eccentric exercise

Journal of Applied Physiology

Volumn 106, Issue 6, 2009, Pages 2068-

  Murphy, Robyn M ^a   Lamb, Graham D ^a  

^a LA TROBE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALPAIN 2; CALPAIN 3; MESSENGER RNA; MUSCLE PROTEIN;

AUTOLYSIS; ECCENTRIC MUSCLE CONTRACTION; ENZYME ACTIVATION; ENZYME ACTIVITY; EXERCISE; FATIGUE; GENE EXPRESSION; HUMAN; LETTER; MUSCLE REGENERATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; SARCOMERE; SKELETAL MUSCLE;

AUTOLYSIS; CALPAIN; EXERCISE; GENE EXPRESSION; HUMANS; MUSCLE FATIGUE; MUSCLE PROTEINS; RNA, MESSENGER; SARCOMERES;

EID: 66749171243     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00239.2009     Document Type: Letter

References (6)

1. Feasson L, Stockholm D, Freyssenet D, Richard I, Duguez S, Beckmann JS, Denis C. Molecular adaptations of neuromuscular disease-associated proteins in response to eccentric exercise in human skeletal muscle. J Physiol 543: 297-306, 2002. (Pubitemid 34947315)
2. Garcia Diaz BE, Moldoveanu T, Kuiper MJ, Campbell RL, Davies PL. Insertion sequence 1 of muscle-specific calpain, p94, acts as an internal propeptide. J Biol Chem 279: 27656-27666, 2004. (Pubitemid 38812607)
3. Lehti M, Kivela R, Komi PV, Komulainen J, Kainulainen H, Kyrolainen H. Effects of fatiguing jumping exercise on mRNA expression of titin-complex proteins and calpains. J Appl Physiol 106: 1419-1424, 2009.
4. Murphy RM, Goodman CA, McKenna MJ, Bennie J, Leikis M, Lamb GD. Calpain-3 is autolyzed and hence activated in human skeletal muscle 24 h following a single bout of eccentric exercise. J Appl Physiol 103, 926-931, 2007. (Pubitemid 47358876)
5. 2+] and is not dependent on stretch. J Biol Chem 284: 7811-7819, 2009.
6. Spencer MJ, Lu B, Tidball JG. Calpain II expression is increased by changes in mechanical loading of muscle in vivo. J Cell Biochem 64: 55-66, 1997. (Pubitemid 27082321)