Phosphorylation regulates the ferritoid-ferritin interaction and nuclear transport

Journal of Cellular Biochemistry

Volumn 107, Issue 3, 2009, Pages 528-536

  Beazley, Kelly E ^a   Nurminskaya, Maria ^a   Linsenmayer, Thomas F ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Cornea; Ferritin; Ferritoid; Nucleus; Phosphorylation

Indexed keywords

CARRIER PROTEIN; DNA; FERRITIN; FERRITOID; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EXPERIMENTAL MODEL; MOLECULAR MECHANICS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SEQUENCE ANALYSIS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; CHICK EMBRYO; COS CELLS; DNA, COMPLEMENTARY; FERRITINS; IRON; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; PHOSPHORYLATION; TRANSFECTION;

AVES;

EID: 66749150525     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22154     Document Type: Article

References (27)

1. Beazley KE, Nurminskaya M, Talbot CJ, Linsenmayer TF. 2008. Corneal epithelial nuclear ferritin: Developmental regulation of ferritin and its nuclear transporter ferritoid. Dev Dyn 237:2529-2541.
2. Cai CX, Linsenmayer TF. 2001. Nuclear translocation of ferritin in corneal epithelial cells. J Cell Sci 114:2327-2334. (Pubitemid 32633703)
3. Cai CX, Birk DE, Linsenmayer TF. 1997. Ferritin is a developmentally- regulated nuclear protein of avian corneal epithelial cells. J Biol Chem 272:12831-12839. (Pubitemid 27203385)
4. Cai CX, Ching A, Lagace C, Linsenmayer T. 2008. Nuclear ferritin-mediated protection of corneal epithelial cells from oxidative damage to DNA. Dev Dyn 237:2676-2683.
5. Cazzola M, Bergamaschi G, Dezza L, Arosio P. 1990. Manipulations of cellular iron metabolism for modulating normal and malignant cell proliferation: Achievements and prospects. Blood 75:1903-1919. (Pubitemid 20180277)
6. Chijiwa T, Mishima A, Hagiwara M, Sano M, Hayashi K, Inoue T, Naito K, Toshioka T, Hidaka H. 1990. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamy- lamino)ethyl]-5- isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem 265:5267-5272. (Pubitemid 20117183)
7. Evan GI, Lewis GK, Ramsay G, Bishop JM. 1985. Isolation of a monoclonal antibody specific for human c-myc proto-oncogen product. Mol Cell Biol 5:3610-3616. (Pubitemid 16233068)
8. Ferreira C, Bucchini D, Martin ME, Levi S, Arosio P, Grandchamp B, Beaumont C. 2000. Early embryonic lethality of H ferritin gene deletion in mice. J Biol Chem 275:3021-3024. (Pubitemid 30082994)
9. Ford GC, Harrison PM, Rice DW, Smith JM, Treffry A, White JL, Yariv J. 1984. Ferritin: Design and formation of an iron-storage molecule. Philos Trans Roy Soc Lond Ser B Biol Sci 304:551-565.
10. Hamburger V, Hamilton HL. 1951. A series of normal stages in the development of the chick embryo. J Morphol 88:49-92.
11. Harrison PM, Arosio P. 1996. The ferritins: Molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta 1275: 161-203. (Pubitemid 26248989)
12. Hidaka H, Kobayashi R. 1992. Pharmacology of protein kinase inhibitors. Annu Rev Pharmacol Toxicol 32:377-397.
13. Hurley TR, Luo K, Sefton BM. 1989. Activators of protein kinase C induce dissociation of CD4, but not CD8, from p56lck. Science 245:407-409. (Pubitemid 19203364)
14. Lawson DM, Artymiuk PJ, Yewdall SJ, Smith JMA, Livingstone JC, Treffry A, Luzzago A, Levi S, Arosio P, Cesareni G, Thomas CD, Shaw WV, Harrison PM. 1991. Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts. Nature 349:541-544. (Pubitemid 21912103)
15. Li R, Luo C, Mines M, Zhang J, Fan GH. 2006. Chemokine CXCL12 induces binding of ferritin heavy chain to the chemokine receptor CXCR4, alters CXCR4 signaling, and induces phosphorylation and nuclear translocation of ferritin heavy chain. J Biol Chem 281:37616-37627. (Pubitemid 46042064)
16. Linsenmayer TF, Cai CX, Millholland JM, Beazley KE, Fitch JM. 2005. Nuclear ferritin in corneal epithelial cells: Tissue-specific nuclear transport and protection from UV-damage. Prog Retin Eye Res 24:139-159. (Pubitemid 40018222)
17. Luzzago A, Cesareni G. 1989. Isolation of point mutations that affect the folding of the H chain of human ferritin in E. coli. EMBO J 8:569-576. (Pubitemid 19274977)
18. Mann M, Ong SE, Gronborg M, Steen H, Jensen ON, Pandey A. 2002. Analysis of protein phosphorylation using mass spectrometry: Deciphering the phosphoproteome. Trends Biotechnol 20:261-268. (Pubitemid 34451062)
19. Millholland JM, Fitch JM, Cai CX, Gibney EP, Beazley KE, Linsenmayer TF. 2003. Ferritoid, a tissue-specific nuclear transport protein for ferritin in corneal epithelial cells. J Biol Chem 278:23963-23970. (Pubitemid 36830225)
20. Nurminskaya M, Talbot CJ, Nurminsky DI, Beazley KE, Linsenmayer TF. 2009. Nuclear ferritin: A ferritoid-ferritin complex in corneal epithelial cells. Invest Ophthalmol Vis Sci (in press).
21. Schmitz ML, Henkel T, Baeuerle PA. 1991. Proteins controlling the nuclear uptake of NF-kappa B, Rel and dorsal. Trends Cell Biol 1:130-137. (Pubitemid 121001664)
22. Sprang SR, Acharya KR, Goldsmith EJ, Stuart DI, Varvill K, Fletterick RJ, Madsen NB, Johnson LN. 1988. Structural changes in glycogen phosphorylase induced by phosphorylation. Nature 336:215-221.
23. Stohs SJ, Bagchi D. 1995. Oxidative mechanisms in the toxicity of metal ions. Free Radical Biol Med 18:321-336.
24. Surguladze N, Patton S, Cozzi A, Fried MG, Connor JR. 2005. Characterization of nuclear ferritin and mechanism of translocation. Biochem J 388:731-740. (Pubitemid 40941558)
25. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F. 1991. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 266:15771-15781. (Pubitemid 21907725)
26. Zak NB, Linsenmayer TF. 1983. Monoclonal antibodies against developmentally regulated corneal antigens. Dev Biol 99:373-381.
27. Zhao GH, Ceci P, Ilari A, Giangiacomo L, Laue TM, Chiancone E, Chasteen ND. 2002. Iron and hydrogen peroxide detoxification properties of DNA-binding protein from starved cells-A ferritin-like DNA-binding protein of Escherichia coli. J Biol Chem 277:27689-27696. (Pubitemid 34966712)