Standardization of allergen products: 1. Detailed characterization of GMP-produced recombinant Bet v 1.0101 as biological reference preparation

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 64, Issue 7, 2009, Pages 1038-1045

  Himly, M ^a   Nony, E ^b   Chabre, H ^b   Van Overtvelt, L ^b   Neubauer, A ^c   Van Ree, R ^d   Buchheit, K H ^e   Vieths, S ^f   Moingeon, P ^b   Ferreira, F ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

^b Stallergenes SA   (France)

^c BIOMAY AG   (Austria)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e European Directorate for the Quality of Medicines and Health Care   (France)

^f PAUL EHRLICH INSTITUT   (Germany)

Author keywords

CREATE; EDQM; Good manufacturing practice; Ph. Eur. reference standard; Recombinant Bet v 1 allergen

Indexed keywords

AMINO ACID DERIVATIVE; IMMUNOGLOBULIN E; RECOMBINANT ALLERGEN; RECOMBINANT BET V 1 ALLERGEN; UNCLASSIFIED DRUG;

ALLERGY TEST; ARTICLE; BASOPHIL ACTIVATION TEST; BIOLOGICAL ACTIVITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DEAMINATION; DENATURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL PERMEATION CHROMATOGRAPHY; GOOD MANUFACTURING PRACTICE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOREACTIVITY; ISOELECTRIC FOCUSING; LIGHT SCATTERING; MASS SPECTROMETRY; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN STABILITY; QUALITY CONTROL; STANDARDIZATION; T LYMPHOCYTE ACTIVATION;

ALLERGENS; ANTIGENS, PLANT; BASOPHILS; CLONING, MOLECULAR; HUMANS; IMMUNOGLOBULIN E; RECOMBINANT PROTEINS; REFERENCE STANDARDS;

EID: 66749110446     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2009.01957.x     Document Type: Article

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